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Showing papers in "American Journal of Obstetrics and Gynecology in 1981"


Journal Article•DOI•
TL;DR: The treatment of hirsutism resulting from functional ovarian hyperandrogenism is not as satisfactory; estrogen-progestin treatment is the most useful adjunct to cosmetic approaches to hirsUTism in this country.

919 citations


Journal Article•DOI•
TL;DR: As an alternative to hysterectomy in patients with excessive bleeding, the endometrium was destroyed by means of the neodymium-YAG laser by finding the human uterus having a thick myometrium to be ideal for this modality.

468 citations


Journal Article•DOI•
TL;DR: By providing experimental evidence for the presence of estradiol receptors in the lower uninary tract, the present data advance the case forEstradiol therapy in incontinent patients.

350 citations


Journal Article•DOI•
TL;DR: The rise in plasma ACTH concentrations, asregnancy advances, is suggestive of the possibility that a source of ACTH exists that is not subject to negative feedback control, that the clearance of free cortisol increases as pregnancy advances, or that there is an alteration in the metabolism of the ACTH precursor protein produced by the pituitary and/or placenta.

332 citations


Journal Article•DOI•
TL;DR: The hypothesis that premature cessation of ovarian function increases the risk of nonfatal myocardial infarction is supported.

317 citations


Journal Article•DOI•
TL;DR: The results indicate that MHC homozygosity between spouses is associated with postfertilization pregnancy wastage in humans.

308 citations


Journal Article•DOI•
TL;DR: The results of this study indicate that rhesus monkeys with spontaneous endometriosis have an altered cellular immune response to autologous antigens, and suggest that endometrial cells translocated from their normal location may implant only in women with specific alteration in cell-mediated immunity.

284 citations


Journal Article•DOI•
TL;DR: Prostaglandin synthetase activity was assayed in homogenates prepared from human fetal membranes and uterine decidua tissues with [14C] arachidonic acid used as substrate and the specific activities of this enzyme in chorion laeve andDecidua vera tissues obtained before and after labor were high, whereas 15-hydroxyprostaglandsin dehydrogenase activity in amnion was low.

281 citations


Journal Article•DOI•
TL;DR: It is demonstrated that lower than maximum doses of danazol produce similar beneficial effects in the treatment of endometriosis, and with the low dosages, the patient did not achieve freedom from side-effects.

245 citations


Journal Article•DOI•
TL;DR: Overall, 26 of 31 IUGR fetuses demonstrated decreased qualitative AFV, and perinatal morbidity was increased tenfold in patients with decreased AFV.

236 citations


Journal Article•DOI•
TL;DR: Proper screening and therapy are essential in all girls with menorrhagia, and conventional methods of hormonal control are only partially effective in these special cases.

Journal Article•DOI•
TL;DR: It is inappropriate to continue to refer to danazol as a "selective antigonadotrophin," as this steroid has direct effects on hypothalamic-pituitary function, multiple classes of steroid receptors, gonadal steroidogenesis, and endogenous steroid metabolism.

Journal Article•DOI•
TL;DR: The data suggest a causal relationship between GBS colonization and events leading to preterm birth and the possible impact of eradication of colonization with GBS on prematurity.

Journal Article•DOI•
TL;DR: A descriptive study in which amenorrheic runners were compared to regularly menstruating runners and nonrunning control subjects with regard to body composition, psychologiCal profiles, dietary habits, and basal peptide and steroid hormone concentrations.

Journal Article•DOI•
TL;DR: A comparison of simultaneous direct ECG and ultrasound records shows that the latter provide reasonable statistical measures of heart period variation, and also of accelerations and decelerations provided that signal loss is taken into account.

Journal Article•DOI•
TL;DR: Preliminary recurrence/survival data suggest that the identification of patterns and subpatterns has no prognostic significance, nor is there evidence that adenocarcinoma (or adenosquamous carcinoma) metastasizes earlier, metastasizing more frequently, or is more radioresistant.

Journal Article•DOI•
TL;DR: Persistence of normal circadian rhythmicity in spite of a continuously elevated FFI and resistance to dexamethasone suppression suggest control of cortisol secretion by normal regulatory mechanisms in pregnancy with resetting of the maternal feedback mechanisms to higher levels.

Journal Article•DOI•
TL;DR: A PR assay may be used to help select the most appropriate therapy for patients with recurrent or advanced endometrial adenocarcinoma, and a statistically significant relationship has been demonstrated between the presence of specific cytoplasmic PR and response to progestin therapy in recurrent orAdvanced endometria.

Journal Article•DOI•
TL;DR: Covariate and multivariate analyses of tumor type, age at diagnosis, duration of follow-up, abdominal tumor surgery, abdominal radiotherapy, number of chemotherapeutic agents administered, and cumulative doses of several drugs revealed that the location of the ovaries relative to radiation treatment fields was the only risk factor for subsequent ovarian failure.

Journal Article•DOI•
TL;DR: The results of a prospective clinical management based on fetal biophysical profile scoring method was evaluated and suggest that this method can be used effectively to screen and manage a high-risk population.

Journal Article•DOI•
TL;DR: Favorable experience with a new pressure technique, with the use of the bicycle seat stool, has led to reversal of primary therapy of vaginal agenesis and stenosis from a surgical to a nonsurgical approach.

Journal Article•DOI•
TL;DR: It is proposed that oxytocin provides the stimulus for the accelerated prostaglandin production in decidua and fetal membranes at the onset of labor.

Journal Article•DOI•
TL;DR: Of 421 patients with posthysterectomy enterocele and vault prolapse, 190 cases are reported for the first time; 88% of the operations provided good vaginal support and a satisfactory result.

Journal Article•DOI•
TL;DR: A growth curve of the calcified section of femur was constructed which indicated that gestational age could be predicted with 95% confidence limits to +/- 6.7 days, and a new parameter for estimating fetal age by ultrasound which would appear to be as accurate as that of biparietal diameter is proposed.

Journal Article•DOI•
TL;DR: Flow per unit of fetal weight was constant during pregnancy until 36 to 37 weeks, when a reduction occurred, and was maximal between 37 and 38 weeks, then decreased during the last 2 weeks of pregnancy.

Journal Article•DOI•
TL;DR: It is proposed that the formation of gap junctions may be stimulated by some physiologic change and may terminate pregnancy by resulting in coordinated, synchronized muscle activity and dilatation of the cervix followed by expulsion of the fetus.

Journal Article•DOI•
TL;DR: The data suggest that the presence of microorganisms in the amniotic fluid of afebrile patients in premature labor with intact membranes represents an infectious process rather than an innocuous condition and raises questions with regard to current obstetric trends in the management of premature labor.

Journal Article•DOI•
TL;DR: Peritoneal cytologic examination appears to be an important factor in the prognosis of endometrial cancer and, when the washings are positive for malignant cells, intraperitoneal chronic phosphate therapy seems to be efficacious.

Journal Article•DOI•
TL;DR: Ovarian failure, followed by Rokitansky syndrome and then physiologic delay, are the most frequently encountered etiologies and subsequent reproductive potential of each diagnostic group is limited.

Journal Article•DOI•
TL;DR: It is suggested that oxytocin stimulates PGF production in the pregnant uterus when it is appropriately sensitized to Oxytocin, causing a potention of the oxytocIn-induced contractions which is necessary for the contractions to become efficient in dilating the cervix.