Showing papers in "Biosensors and Bioelectronics in 1990"

TL;DR: A planar array of microelectrodes developed for monitoring the electrical activity of cells in culture is described, and it was found that extracellular stimulation of the cells was possible via the same electrodes used for recording.

TL;DR: It was demonstrated that the internal diffusion of hydrogen peroxide through the polypyrrole layer to the platinum surface was the main limiting factor controlling the magnitude of the response of the biosensor to glucose.

TL;DR: A new detection method is presented for the detection of an immunological reaction taking place in a membrane, which covers the gate area of an ISFET, which gives direct information about specific charge properties of the macromolecules to be studied.

TL;DR: New data on the analysis of nicotine, fluoride ion, and some organophosphorus compounds are reported using the present AChE sensor based on the inhibition of the immobilized acetylcholine esterase.

TL;DR: Immobilization of glucose oxidase in electropolymerized polypyrrole film on the surface of a platinum wire electrode, provides a convenient sensor for flow-injection glucose determination and allows quick electrode renewal before each series of measurements.

TL;DR: The recent development of piezoelectric devices as biosensors is reviewed in this article, where a thorough understanding of the different phenomena associated with crystals frequency measurement in biological reactions is still lacking and deserves further investigation.

TL;DR: In this paper, a method was described for the entrapment of whole banana cells in a polypyrrole film electrochemically deposited on a gold electrode. And the polyphenol oxidase activity of the incorporated whole cells in the polymer was studied using dopamine as the major substrate.

TL;DR: A potentially wearable glucose sensor was developed, consisting of an oxygen electrode as detector and a dynamic enzyme perfusion system as selector, where the problems of enzyme instability and oxygen limitation might be circumvented.

TL;DR: In this article, a fast-responding glucose biosensor is presented based on an oxygen optrode, which measures the consumption of oxygen via dynamic quenching of the fluorescence of an indicator by molecular oxygen.

TL;DR: A theoretical model is developed for an electrochemical sensor for toxic substances which works by measuring the inhibition of the enzyme activity and a complete set of analytical solutions is found which corresponds to a number of different rate limiting processes.

TL;DR: It is shown that an inhibited enzyme electrode, using cytochrome oxidase, will respond to H2S, HCN and azide ion and values of the concentration of inhibitor are obtained in a matter of seconds after exposure of the sensor.

TL;DR: In this article, the authors used the enzyme glucose oxidase (GO) and the polymer poly[vinyl alcohol] (PVAL), with and without the polyfunctional monomer, allyl methacrylate (AM), to detect H 2 O 2 at 300 mV vs Ag/AgCl.

TL;DR: In this article, electrogenerated polytyramine (PTy, tyramine = p-(2-aminoethyl)-phenol) modified electrodes were used for human immunoglobulin G (IgG) detection.

TL;DR: A new calorimetric sensor has been developed which employs a thin-film thermopile in association with an immobilized enzyme to generate an equivalent proportional voltage response to glucose concentrations present in either buffer solution or blood.

TL;DR: In this paper, a multigate proton and fluoride ion sensitive field effect transistors (ENFETs) were assembled by immobilizing enzymes to a multi-proton and fluorine ion sensitive FET.

TL;DR: In this article, the authors demonstrate how fish scales can be used to monitor catecholamine levels in human blood plasma, and discuss other potential biosensor applications of this intact biological receptor-effector system.

TL;DR: In this article, an anti-HSA immunoglobulin G (IgG) antibody was detected by a cooled charge-coupled device (CCD) as a change in the fluorescence intensity.

TL;DR: An inhibition enzyme electrode to measure toxic gases can be constructed using the respiratory enzyme cytochrome oxidase using a gold electrode modified with the mediator bis(4-pyridyl) disulphate.

TL;DR: In this article, a fiber optic fluorometer is combined with a solid membrane reactor that retains enzymes (dehydrogenases) as well as macromolecular adenine dinucleotide coenzyme derivatives, e.g. PEG (MW 20 000)-N6-(2-aminoethyl)-NAD(H), in the direct vicinity of the sensor tip.

TL;DR: The potential of five different groups of materials (carbons, glass and ceramics, polymers, hydrogels and collagen) as biomaterials in artificial implant applications is examined in this article.

TL;DR: In this article, an ethanol enzyme electrode which uses the organic conducting salt NMP TCNQ as electrode material is described, which is optimized with regard to NAD concentration in solution, the enzyme concentration behind the membrane and the pore size of the membranes covering the electrode.

TL;DR: In this article, the structure and function of the epidermis of the newborn rat are examined as a model for studies of the human state, and the spatial alignment of these macromolecular arrays is demonstrated to be a function of physiological tensions.

TL;DR: Results are presented on the development of a novel biosensor which will use neurons or neuronal components as both the recognition elements and primary transducers for analyte quantitation, demonstrated and evaluated by exposing identified neurons from the visceral ganglia of the pond snail Limnea stagnalis to the model analyte serotonin.

TL;DR: When used in sera the probe showed no interference from electroactive compounds present in blood, and also showed good stability and reproducibility, which make this sensor appropriate for continuous extracorporeal circuit blood monitoring of succinylcholine during surgery.

TL;DR: In this article, four-channel and 12-channel printed-circuit microelectrodes have been micromachined in silicon with polysilicon conductors and silicon nitride insulation.

TL;DR: With appropriate conditions very significant improvements in detection times are shown with typical detection thresholds of 300 min for start concentrations of 10(2), which is superior in terms of potential test costs, sample handling and sample transport.

TL;DR: In this paper, a very high resolution of greater than 5 × 10−9 was obtained over a conductivity band of 6 mS cm−1 in the range 1·4−22 mScm−1.

TL;DR: In this paper, the preparation of a compound liquid ion exchanger used for the miniaturization of bile acid sensitive microelectrode is described, and the slopes, detection limits, selectivity coefficients, drifts and response time of the various bile acidsensitive micro electrodes are evaluated and compared.