Showing papers in "Experimental Parasitology in 1976"

TL;DR: A new technique for estimating the absolute level of parasitemias in trypanosome infections is described, achieved by matching microscopic fields of a wet blood film against charts and, where fewer organisms are present, by counting the number oftrypanosomes in 5, 10, or 20 microscope fields.

TL;DR: Toxoplasma gondii, strain RH, produced plaques in human fibroblast tissue cultures over the temperatures 30–41 C, and both mutants that were tested were found to be markedly less virulent for mice than was the wild type RH strain.

TL;DR: This is the first reported axenic culture of this common human intestinal parasite and pathogen; its study in pure culture is now possible.

TL;DR: In this study the presence of two circulating schistosome derived antigens, probably both polysaccharides, was demonstrated in hamsters heavily infected with Schistosoma mansoni.

TL;DR: The weight of current evidence suggests that elicitation or absence of this cellular response resides in the recognition or nonrecognition of the sporocyst as a foreign body as well as the particular frequencies of relevant genes in the populations concerned.

TL;DR: The diversity and prevalence of permanent stable symbioses support the concept that there are many precedents for the steps hypothesized in the serial endosymbiotic theory of the origin of eukaryotic cells.

TL;DR: Germfree guinea pigs inoculated orally and intracecally with Blastocystis hominis and the enteric flora from symptomatic patients believe B. hominis may occasionally be related causally to the production of such symptoms by a mechanism not completely understandable.

TL;DR: The results show that O2 uptake is not essential for the survival of trypanosomes in rats and they support the idea that bloodstream tryPanosomes have an alternative pathway for glycolysis, allowing energy production in the absence of respiration.

TL;DR: It appears that experimental filariasis may induce suppressor cell activity that inhibits lymphocyte proliferation in vitro that is inversely correlated to the appearance of filarial-antigen sensitive cells in the spleen.

TL;DR: The demonstration that a surface receptor on the erythrocyte controls the parasite's ability to invade the ERYthrocytes suggests that such a mechanism may underlie the host specificity in other Sporozoa.

TL;DR: The surface of Fasciola hepatica, therefore, has morphological and chemical features very like those proposed for the “greater membrane” by Lehninger.

TL;DR: Spore germination tests in blood plasma indicated that it is unlikely that spores injected by an infected mosquito bite would result in an infection.

TL;DR: Mice concurrently infected with the rodent piroplasms Babesia hylomysci or B. microti during a primary infection with the nematode Trichuris muris showed marked immunodepression, and the normal immune expulsion of the Nematode was delayed.

TL;DR: The pattern of response of all strains was very reproducible, indicating genetic control of the anaphylactic antibody production to the infection, and an inverse relationship between the number of larvae recovered from a given strain and their reaginic antibody titer was observed.

TL;DR: Following encapsulation of a nematode parasite Neoaplectana carpocapsae by larval Aedes aegypti, there were significant decreases in both the total hemocyte count and in the number of DOPA-oxidase positive hemocytes within the anal papillae.

TL;DR: Absorption of l -methionine in the duodenum of intestine of chicks infected with Eimeria acervulina was markedly less than in uninoculated controls or birdsinfected with E. tenella.

TL;DR: It is shown that sporozoites undergo changes subsequent to penetration of host cells that render them susceptible to drug action, and that the number and condition of sporozoite in the nontreated cultures were unchanged at 24 hr postinoculation.

TL;DR: Hematological changes observed during detailed studies of the course of infection in eight calves, three of which subsequently died, included thrombocytopenia, leucopenia, and reduced fibrinogen levels, established the occurrence of disseminated intravascular coagulation in the acute infections studied.

TL;DR: No evidence was found for the involvement of any cell organelle in glycogenesis, but preformed glycogen may have acted as a “template” for further synthesis, and the mechanism of protein synthesis appeared to resemble the GER-Golgi mediated mechanism of vertebrates.

TL;DR: The development of delayed hypersensitivity in rabbits infected with Eimeria stiedai was shown by skin testing and Histological examination of dermal reactions revealed mononuclear cell infiltration within 48 hr with areas of necrobiosis.

TL;DR: Examination of eight strains of axenically grown Blastocystis hominis by Nomarski interference optics revealed the presence in all strains of intracellular bacterialike spheres and rods, which were named alpha, which was confirmed by transmission and freeze fracture electron microscopy.

TL;DR: The results suggest that other species of malaria may develop resistance to clindamycin or minocycline, however, it should not invalidate the use of the other in the treatment of malaria.

TL;DR: Serum levels of antisporozoite antibodies (CSP and SNA) increased during immunization of the intact animals and that of intact animals immunized and found resistant to sporozoite challenge was used for passive transfer studies.

TL;DR: The structure of the Capillaria hepatica egg shell was studied with the electron microscope and correlated with light microscope histochemical observations, finding both fibrous and nonfibrous components, both of which stain for protein.

TL;DR: The head gland of the cercaria of Schistosoma mansoni appears to be a relatively large unicellular entity consisting of a fundus tapering into a system of multiple ducts that opens into the integument at the anterior end of the oral sucker.

TL;DR: The delayed hypersensitivity response, measured by footpad swelling, to an optimum intravenous sensitizing dosage of SRBC was inhibited in mice sensitized 10 days after Ascaris infection, but not inhibited in mouse sensitized at 21 or 32 days after infection.

TL;DR: Larvae of Angiostrongylus cantonensis cause histopathologic changes in Lymnaea palustris, being characterized by mechanical damage to cells and nonspecific cellular responses to the larvae.

TL;DR: It is hypothesized that lysis of extravascular parasites, possibly due to agglutination by variant-specific antibody, releases parasite enzymes into host tissues, resulting in the observed increase in serum enzyme levels.

TL;DR: It is postulated that the synthesis of the antigen “5” may occur in specialized cells of both the germinal “membrane” and the protoscoleces of the hydatid cysts, which seems to be involved in the transfer of the substance to the cystic cavity.

TL;DR: Secretions from the preacetabular glands of cercariae of Schistosoma mansoni were collected over skin surface lipid on a warmed glass surface in a system providing a temperature gradient, with proteolytic activity linear with respect to the numbers of cerbariae secreting.