Showing papers in "Hepatobiliary & Pancreatic Diseases International in 2013"

TL;DR: The BISAP predicts severity, death, and especially organ failure in acute pancreatitis as well as APACHE-II does and better than Ranson criteria, CTSI, CRP, hematocrit, and BMI.

TL;DR: Endobiliary radiofrequency ablation seems to be safe and feasible as a palliative measure and may prolong the stent patency and overall survival in patients with malignant biliary obstruction due to inoperable extrahepatic cholangiocarcinoma.

TL;DR: Propofol decreases hepatocellular carcinoma cell invasiveness, which is partly due to the down-regulation of MMP-9 expression by miR-199a.

TL;DR: Notch1 expression might be an independent predictor of both short disease-free survival and shorter disease-specific survival in HCC patients after curative resection and could be used as an immunohistochemical biomarker to detect patients with a high-risk of recurrence.

TL;DR: Future advancement of NAFLD therapy should focus on the mechanistic studies on cell based and animal models and human clinical trials of exercise, as well as the combination of lifestyle intervention and pharmaceutical therapy specifically targeting main signaling pathways related to lipid metabolism, oxidative stress and inflammation.

TL;DR: Both G PC-3 overexpression and GPC-3 mRNA abnormality could be used as markers for the diagnosis of HCC and monitoring its metastasis.

TL;DR: Genetic and tumor biological diversity exists in PDAC according to the tumor localization, and two PDAC cell lines are presented as typical representatives originating from pancreatic head and body/tail cancers, respectively.

TL;DR: Wider preoperative portal vein diameter, postoperative thrombocytosis, prolonged prothrombin time and periesophagogastric devascularization are independent risk factors of PVT, which is related with higher risk of postoperative gastrointestinal hemorrhage but has no significant impact on the overall survival.

TL;DR: NAFLD is associated with increased concentration of plasma lipids and upregulation of hepatic cav 1 and SR-B1 gene and protein expressions, which indicate that cav1 and SR -B1 might play crucial roles in the pathogenesis of NAFLD.

TL;DR: DM is an independent factor in the progression of cirrhosis to HCC, but the role may be contrary to the current viewpoint.

TL;DR: ARFI can accurately and objectively assess the elasticity of lesions by obtaining the shear wave elastic value of FLL with VTTQ and is a novel, simple, noninvasive and useful diagnostic method for the characterization of Fll.

TL;DR: Modern technologies mentioned in this paper are the key tool for achieving precise liver resection and can effectively lead to maximum preservation of anatomical structural integrity and functions of the remnant liver.

TL;DR: EP decreases intestinal permeability, and inhibits the release of multiple proinflammatory cytokines in rats with ALF, and has protective and therapeutic effects on intestinal mucosa.

TL;DR: The overexpression of IQGap1 may play an important role in pancreatic cancer occurrence and progression, and IQGAP1 may serve as a novel molecular target for the diagnosis and treatment of Pancreatic cancer.

TL;DR: Although clinical operational tolerance is still rare in liver transplantation recipients, ongoing basic research and collaborative clinical trials may help to decipher the mystery of transplantation tolerance and extend the potential benefits of drug withdrawal to an increasing number of patients in a more predictable fashion.

TL;DR: Surgical treatment is safe and feasible for treatment of IVCTT in patients with hepatocellular carcinoma, and surgical resectability can be judged according to the classification of tumor thrombus.

TL;DR: ADSCs transplantation improved the survival rate and the liver function of rabbits with ACLF and Xenogenic ADSCs have therapeutic efficacy in the ACLF rabbit model.

TL;DR: The role of newer anti-diabetic agents in treatment of non-alcoholic fatty liver disease is summarized and liraglutide and Exenatide showed improvement in transaminases as well as histology in patients with NASH.

TL;DR: The increase in the serum biomarkers of dementia in the POCD patients supports the hypothesis that chronic cognitive defects are due to a process similar to that seen in Alzheimer's disease.

TL;DR: The grading recommended by the ISGPF is useful for comparing the clinical severity of fistula and for analyzing the clinical and economic consequences of pancreatic fistula.

TL;DR: Although the high-score group had significantly more early postoperative complications, the two groups had comparable hospital mortality and similar satisfactory rates of graft survival and patient overall survival and a high MELD score should not be a contraindication to right-lobe LDLT if donor risk and recipient benefit are taken into full account.

TL;DR: In HBeAg-negative patients with ACLF, the short-term efficacy of entecavir versus lamivudine was similar and the degree of pretreatment liver failure significantly affected the outcome of treatment.

TL;DR: An algorithm is proposed, based on GBA pathological pattern (diffuse, segmental, localized or fundal), suitable for decision-making, suitable for diagnosis and treatment of GBA and its correlation with malignancy.

TL;DR: It is found that HBsAg and anti-HCV seropositivity significantly increased risk of PC, and HBsAb and HBeAb seropposivity may be the protective factors against PC.

TL;DR: In the current era, interpretation of radiologic response after LRT for HCC does not correlate accurately with histologic tumor necrosis; therefore, evolution in its performance is needed.

TL;DR: HUS provided better imaging of BA and should be considered as a primary modality in the differential diagnosis of infantile jaundice, and was important in the diagnosis of BA.

TL;DR: In this article, the authors investigated the potential association between the human telomerase reverse transcriptase (hTERT) rs2736098[A] polymorphism and hepatocellular carcinoma.

TL;DR: Endoscopic therapy is effective in the majority of biliary complications relating to liver transplantation, with equivalent endoscopic treatment response and outcomes for both groups.

TL;DR: S1P1 overexpression or ERp29 absence is related to the carcinogenesis and progression, and may be potential biomarkers for early detection of gallbladder adenocarcinoma.

TL;DR: In consideration of blood loss, SBP, base excess and HCO3-, a CVP of 2.1-3 mmHg was optimal in patients undergoing partial hepatectomy for HCC, and blood oxygenation decreased significantly when the CVP was reduced.