Showing papers in "Human Pathology in 1987"
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TL;DR: Endothelial cells constitute not only the first barrier between the blood and the extravascular space but also serve as a source of molecules influencing the structural and functional integrity of the circulation.
367 citations
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TL;DR: The diffuse ependymal and/or subpial distribution of CMV in several patients suggests additional dissemination via the cerebrospinal fluid, and isolated inclusion-bearing cells may reflect the relative nonpermissiveness of surrounding central nervous system parenchyma for CMV infection.
217 citations
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TL;DR: The possible role of autoimmunity in collagenous colitis should be investigated because of the following circumstantial evidence: the overwhelming female predominance; the frequent presence of possible immunologically mediated disorders such as thyroid and joint disease; the resemblance of surface epithelial changes to those in celiac disease; and the response to corticosteroids.
200 citations
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TL;DR: The morphologic and immunohistochemical features of the rhabdoid tumor are diagnostic of MRT, an entity of unknown histogenesis that has not been reported previously as a primary neoplasm of the CNS.
189 citations
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TL;DR: Heart hearts from the cases of cocaine-associated death contained significantly more myocardial contraction bands, and the diffuseness of the contraction bands correlated directly with the level of cocaine found in the urine and blood at autopsy during routine screening.
184 citations
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TL;DR: The clinical setting, gross organ distribution, and microscopic pathologic findings of disseminated Mycobacterium avium-intracellulare (MAI) infection are described at autopsy in 12 patients with acquired immunodeficiency syndrome (AIDS).
176 citations
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TL;DR: The presence of activated macrophages and T lymphocytes in the fatty streaks indicates that components of a cell-mediated immune response are present and may be important in the pathogenesis of human atherosclerosis.
166 citations
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TL;DR: Whether attributable to events in the intra- or extra-vascular space, the result is the same: abnormal clotting and fibrinolysis whose consequences may include protection from host inflammatory cells, modulation of the immune response, and induction of angiogenesis.
160 citations
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TL;DR: The findings suggest that the grading of adenoid cystic carcinoma of the breast may be important in prognosis and treatment selection.
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TL;DR: Findings indicate that adenomyoepithelioma is a benign tumor that can be adequately treated by complete local excision and remain well from 0.5 to 5.5 years after diagnosis.
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TL;DR: It is concluded that expression of NK markers occurs exclusively in a proportion of T-cell lymphomas, but not B-cell or null cell lymphomas.
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TL;DR: A 40-year-old homosexual man with the acquired immunodeficiency syndrome (AIDS) presented with dyspnea and renal insufficiency and died 3 days after admission, with the combination of membranoproliferative glomerulonephritis and plexogenic pulmonary arteriopathy not described in AIDS to date.
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TL;DR: Specimens from 53 cases of prostatic carcinoma obtained during total prostatectomy or transurethral resection of prostate were analyzed for neurendocrine differentiation with immunocytochemical tests for serotonin, neuron-specific enolase, and chromogranin as well as with the Churukian-Schenk argyrophil reaction.
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TL;DR: Overweight placentas were associated with the following neonatal evidences of acute antenatal hypoxia: low Apgar scores, the respiratory distress syndrome, neurologic abnormalities, and neonatal death.
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TL;DR: Findings indicate that markedly enhanced p21 expression is associated with the earlier stages (invasion and dissemination) of aggressive breast cancers.
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TL;DR: Amiodarone lung is primarily an interstitial pneumonia, and foamy alveolar macrophages and cytoplasmic lamellar inclusions are characteristic, but neither is specific, and their presence alone does not distinguish toxic from nontoxic patients.
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TL;DR: The balance of all components--vessel wall, platelets, adhesive and coagulation proteins, regulatory mechanisms--determines the effectiveness of the hemostatic plug in maintaining the structural and functional integrity of the circulatory system.
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TL;DR: Three cases of Sjögren's syndrome-like illness occurring in patients with the acquired immunodeficiency syndrome (AIDS)-related complex (ARC) are described.
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TL;DR: This article describes one such unusual occurrence of FMD in the coronary arteries with spontaneous dissection and myocardial infarction.
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TL;DR: It is intriguing to consider the possibility that this commitment process could require the release of cells from the intrinsic inhibitory effects of heparan sulfate located around the cells or the synthesis of growth factors secreted by the smooth muscle cells themselves.
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TL;DR: "Mesenchymal" cells and hyaline cells of pleomorphic adenoma and indifferent cells of adenoid cystic carcinoma were negative for both actin and myosin but positive for vimentin and occasionally also positive for keratin.
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TL;DR: The authors propose that, as occurs in tertiary neurosyphilis and general paresis of the insane, Borrelia species may invade the brain, remain in a latent state for many years, and cause dementia in the absence of other focal neurologic deficits.
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TL;DR: The results emphasize the heretofore unrecognized estrogenicity and potential teratogenicity of triphenylethylene antiestrogens on the developing human genital tract and emphasize the need for caution to prevent inadvertent exposure of the developing fetus to these compounds.
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TL;DR: Non-protease-enhanced stains for keratin and EMA allow separation of germ cell and somatic carcinomas, despite their shared capacity for PLAP expression in somatic neoplasms.
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TL;DR: Sulfated GAGs have been shown to be associated with the amyloidotic lesions of Alzheimer's disease, the neuritic plaques, the neurofibrillary tangle, and the congophilic angiopathy.