Showing papers in "Journal of Affective Disorders in 1981"

TL;DR: Life events reported to have occurred 6 months before the onset of illness were compared in 40 outpatients who had a first episode of primary depression and a matched normal control group, consistent with the view that certain recent life events play a substantial role as precipitants in some depressed patients.

TL;DR: Depression scores in subjects were strongly linked with lower maternal care and with maternal overprotection, whether the maternal characteristics were judged by the subjects or by the mothers themselves, and the validity of the PBI as a measure of actual parental characteristics was supported.

TL;DR: Women who became clinically depressed later in the puerperium had higher depression and lability ratings, and a more pronounced day 5 peak, than those who did not.

TL;DR: Plasma levels of gamma-aminobutyric acid (GABA) were determined in 34 clinically symptomatic patients with diagnosis of affective disorder and in 20 normal controls, finding lowest levels were found in patients with familial pure depressive disease and in depression spectrum disease.

TL;DR: Findings argue against a common clinical stereotype that equates all chronic depressions with character disorder.

TL;DR: The incidence of diseases in the medical subspecialities of endocrinology, neurology, cardiology, gastroenterology, and rheumatology appears to be increased in patients with depression, and a causal relationship has been suggested.

TL;DR: The hypothesis that disorders in the community are more likely to be cases of distress is tested and it is predicted that the association between such cases and social adversity will be stronger than for psychiatric out-patients and the difference will be accounted for by the differences in clinical picture between the groups.

TL;DR: The results support, at the subsyndromal level, Winokur's separation of disorders with +FH for alcoholism from those with -FH for affective illness, and data suggest the DSM-III concept of 'dysthymia' is too broad and needs further distinctions among several subaffective and nonaffective chronic depressions.

TL;DR: An antidepressant effect of bromocriptine is suggested although, due to the possibility of Type II error, it may not necessarily be equal to that of imipramine.

TL;DR: It is indicated that lumbar CSF metabolites correlate more with certain individual symptoms than with the global severity of depression, as well as a few other differences by plasma tryptophan level.

TL;DR: Results are compatible with the notion that cognitive therapy initially alters negative thinking and mood, which secondarily leads to improvements in vegetative and motivational symptoms, but further studies are needed to determine if this is a unique effect of cognitive therapy.

TL;DR: The authors systematically evaluated the prevalence and reliabilities of a large set of depressive symptoms and subtypes of major depressive disorder in 40 hospitalized adolescents, aged 12-17, and indicated that the phenomenology of depressive illness in this age group is distinguished by descriptive features akin to traditional clinical formulations.

TL;DR: The personal and family history of bronchial asthma and/or hay fever was obtained from a series of 82 psychiatric patients and there was a significantly higher incidence of atopic disorders in affective patients than in schizophrenic patients.

TL;DR: There are no close relations between these clinical parameters and the biochemical variables except the two mentioned above, and only age proved to be significantly higher in patients with low CSF 5-HIAA, and body height showed the same tendency.

TL;DR: The findings suggest that the differential TSH response to TRH in unipolar and bipolar patients may constitute biological markers of endocrine dysfunction in clinical subgroups of affective disorders.

TL;DR: Results from 121 patients with major depressive disorder followed-up at 6 months with a new comprehensive follow-up schedule, the Longitudinal Interval Follow-Up Evaluation (LIFE) indicate that Forty percent of patients had not recovered from the index episode 6 months after inclusion.

TL;DR: Only in personality patterns did primary non-endogenous depressives show features that have been attributed to reactive depression, and they were significantly more introverted and neurotic than the endogenous depressives, but had lower neuroticism scores than patients with depression secondary to neuroses.

TL;DR: The symptom picture of secondary depression is almost indistinguishable from primary depression, and one important reason a patient enters psychiatric treatment is that he develops a coexistent depression.

TL;DR: The findings from the present study extend the results of previous investigations but demonstrate a functionally intact HPG axis in depressed patients, and suggests that neuroendocrine alterations in depression do not necessarily affect all neuro endocrine axes.

TL;DR: Data fail to replicate suggestions that DST results assist in the selection of either imipramine or amitriptyline, and instead find no significant differences in treatment response between the subgroups.

TL;DR: Familial illness patterns indicated that male and female manics shared the same genetic liability for affective disorder and that X-linked transmission was unlikely.

TL;DR: A logistic model was used to analyze the pattern of affected relatives of probands with primary affective disorders (PAD) and showed a significant baseline increase in frequency of PAD among relatives of P AD proband with siblings more likely to be affected than parents.

TL;DR: The validity of the dexamethasone suppression test was evaluated for the differential diagnosis of primary and secondary depressions and the determination of urinary free cortisol excretion does not improve the performance of the test.

TL;DR: The data suggest that assortative mating is present in the familial transmission of affective disorder.

TL;DR: Families with a two-generational history of affective disorder and well and ill sibs were selected from a population of bipolar manic-depressive patients and typed for HLA antigens, blood groups, serum proteins and red cell enzymes, indicating that close linkage is unlikely for affective Disorder and HLA alleles, haptoglobin, Rh factor, or ABO blood groups.

TL;DR: The results suggest that determination of the pre-treatment tryptophan and tyrosine availability may be superior to diagnostic classification in predicting response to imipramine.

TL;DR: In this paper, the distribution of HLA antigen frequencies in patients with affective disorders was studied and no significant differences between bipolar patients, unipolar patients, or controls were found.

TL;DR: Questions of ascertainment, analytic methods, the X-chromosome map and genetic heterogeneity are examined, finding positive linkage findings cannot be attributed to ascertainment bias or association between affective illness and colorblindness.

TL;DR: While both groups received similar treatments, the primary depressives exhibited a statistically significantly greater degree of recovery than the secondary depressives as measured by these scales.

TL;DR: The authors compared the ABO blood type distribution pattern of 246 manic-depressive patients to that of 6000 controls and found significant differences were found in the distribution of blood groups O and A among the 3 subgroups, and Bipolar-A and B bipolar-C patients also differed from the controls.