Showing papers in "Medicine in 1979"

TL;DR: The glycerol model of acute renal failure in the rabbit was found to differ in several significant ways from ATN in man and may have an entirely different pathogenesis.

TL;DR: Better-tolerated oral nonabsorbable antibiotics, laminar-air-flow rooms, granulocyte transfusions, and chemotherapy and immunotherapy for CMV are among the prophylactic and therapeutic measures that must be critically evaluated in well-controlled, prospective studies.

TL;DR: Hepatic angiosarcoma of the liver is associated with chronic exposure to thorotrast, vinyl chloride, arsenicals, radium and possibly copper and with chronic idiopathic hemochromatosis and although 40% of patients have hepatic fibrosis or cirrhosis at autopsy, the nature of the association between chronic liver disease and hepatic angioedema is unknown.

TL;DR: The leukemogenic potential in man of prolonged cytotoxic agents therapy, especially with alkylating agents, seems to be well established and evidence admonishes against the prolonged use of these drugs in non-fatal disorders.

TL;DR: Therapy is directed at the underlying disorder, but androgen therapy may be helpful in preventing attacks, and future potential therapeutic approaches are discussed.

TL;DR: It is suggested that endocarditis due to fastidious, slow-growing gram-negative rods, Cardiobacterium hominis, Actinobacillus actinomycetemcomitans and Haemophilus species is more common than previously appreciated and frequently goes unrecognized.

TL;DR: The finding that hypophosphatasic children in this kindred had higher circulating total AP activity than adults and were able to model their skeleton normally, together with observations that the bone biopsy in adults had a paucity of osteoblasts, suggests that some factor during growth is able to induce both AP activity and osteoblast function, or, that this disorder is an "abiotrophy" with deficient osteoblastic formation and/or accelerated destruction in adult life.

TL;DR: In vitro and in vivo results support the use of ampicillin, unless the organism produces beta-lactamase, and chloramphenicol is the best choice if the organism is ispicillin-resistant or the patient is penicillin-allergic.

TL;DR: Combinations of carbenicillin plus an aminoglycoside antibiotic are effective for the treatment of infections in neutropenic patients.

TL;DR: It is likely, but not proven, that nephrectomy can be discontinued as a routine pretransplantation procedure in patients with anti-GBM Ab mediated GN and Goodpasture's syndrome.

TL;DR: The one patient who died revealed severe pulmonary fibrosis and talc granulomas in lungs, liver, kidneys and lymph nodes, and Corticosteroid therapy was attempted on two and was ineffective.

TL;DR: Preoperative angiography may increase the accuracy of differentiating this disorder from hypernephroma and may aid the surgeon in planning his approach to kidney resection depending upon the staging of XGP.

TL;DR: Hematin appears to be a promising therapeutic agent for the treatment of acute attack forms of porphyria and subjective improvements in the clinical status of the patients were observed frequently.

TL;DR: It is shown that cumulative sodium balance and aldosterone secretion rates in patients with SIADH are negatively correlated with water intake, and that intracellular osmotically active solute is either lost or "inactivated" in some manner as intrACEllular potassium is replenished.

TL;DR: Persistent greater than two-fold alkaline phosphatase elevation in pancreatitis thus represents a reliable marker of distal common bile duct stenosis, whose sequelae may include cholangitis and secondary biliary cirrhosis and which requires operative intervention in these cases.

TL;DR: The factual coexistence has been illuminated by a review of the pertinent literature and presentation of 12 previously unpublished case reports that concern pulmonary malignancies in PSS and an associated non-pulmonary malignancy.

TL;DR: It is presented a concept that, in familial pheochromocytoma, the metabolism of catecholamines is altered by the process of aging, and that this change modifies the clinical presentations of the disease.

TL;DR: The clinical course of patients with nephrotic syndrome was similar to that usually observed in children and adults with pure minimal change lesions and the prognosis for the patients reported in this series was quite good.

TL;DR: The autopsy and clinical findings in this investigation as well as reported experimental studies suggest that T. glabrata is an organism of low virulence, which appears to be of predictive value as prognostic indices of survival and severity of the infection.

TL;DR: Thirty of 85 children with membranous glomerulonephritis (MGN) had associated extraglomerular disorders and the necessity for further investigations in patients with MGN in order to find an underlying disease is emphasized.

TL;DR: The infectious etiologic agents of gastroenteritis are manifold and have only recently been studied in greater depth, but the recognition of the pathogenicity of enterotoxins has created an awareness of the complexity of gastrointestinal physiology with host-parasite interactions.

TL;DR: In this paper, the impact of aging on the severity of chronic immune-complex glomerulonephritis was studied in 144 patients from whom diagnostic renal biopsies were obtained over a 3-year period.