Showing papers in "Parasitology Today in 1993"

TL;DR: Despite being restricted to the host's first line of defence (the integument, away from vital organs), ectoparasite damage has a pronounced impact on host fitness, which implies that permanent ectopartasites evolve less 'aggressively' than do either nest or field ectoparsites.

TL;DR: Jason Wooden, Susan Kyes and Carol Hopkins Sibley have recently adapted two methods that offer a quick, easy alternative for the identification of P. falciparum strains in the laboratory.

TL;DR: An increase in travel, the Indian and Sudanese epidemics of visceral leishmaniasis, parasite resistance to antimony and the emergence of AIDS-related leish maniasis have all increased the urgency for new drugs, and led to reappraisals of the old ones, as discussed here.

TL;DR: This review looks at alternatives to conventional control of cattle ticks, which make use of the host's innate abilities and methods of immunizing cattle against ticks, supported where necessary by vaccination against TBDs.

TL;DR: Although the vaccine is inappropriate for use in human beings, the manner in which it induces immunity in sheep will prove vital to the authors' understanding of the infection and the eventual development of a suitable vaccine to combat toxoplasmosis in people as well as in animals.

TL;DR: The various types of IGR are reviewed here by Jean-Francois Graf and their mechanism of action, their practical application and their respective advantages and limitations are discussed.

TL;DR: This approach aims to express foreign anti-parasitic or anti-viral gene products in symbiotic bacteria harbored by insects in order to confer refractoriness to vector populations, ie.

TL;DR: The alternative biological and statistical approaches to understanding the present-day distributions of vectors are discussed, and predictions about how these might change with global warming are made.

TL;DR: An overview of the recent progress on the elucidation of mechanisms of drug resistance in the protozoan parasite Leishmania, selected under laboratory conditions is presented.

TL;DR: The ability of the flagellar pocket of the trypanosomatid to accumulate efficiently nutrients obtained from the host as a major factor in the success of this group of parasites is discussed.

TL;DR: How an understanding of the cellular and molecular bases of arrested development may lead to new approaches for the control of ancylostomiasis and related infections is shown.

TL;DR: The expression of trans-sialidase and the acquisition of sialic acid by T. cruzi may be relevant to the interaction of the parasite with the host, and consequently may influence the pathobiology of Chagas disease.

TL;DR: Is this the beginning of another chapter of drug resistance?

TL;DR: It is generally assumed that glycolysis is remarkably similar among all organisms, prokaryotic and eukaryotic, but there is growing evidence that significant deviations from conventional glyCOlysis occur in protists.

TL;DR: Patricia Johnson looks at a variety of mechanisms that lead to reduced susceptibility of these pathogens to the drug metronidozole in anaerobic protozoa and bacteria.

TL;DR: The background to the discovery of Atovaquone is explored, its mode of action, and biological and clinical profiles are reviewed, and the only member of the series to show therapeutic activity in humans when taken orally is reviewed.

TL;DR: Resistance is due to the loss of a drug-activating enzyme that is present in sensitive schistosomes and absent in resistant worms and in the mammalian hosts and further study of this enzyme may yield valuable clues for drug design and for a basic understanding of parasite metabolism.

TL;DR: In this article, Paul Bates reviews recent progress in the axenic culture of amastigotes and addresses some of the remaining problems associated with culture methods for both amostigote and promostigotes forms.

TL;DR: A database compiled from MSA1 sequences from several species used together with sequence comparisons and predicted secondary structure reveals interesting features of this molecule.

TL;DR: In this review, Richard Roush discusses the genetics and management of resistance to insecticides (especially as related to arthropod vectors of human and animal diseases), with the objective of suggesting future directions.

TL;DR: Schapira et al. as mentioned in this paper investigated the epidemiological factors associated with the development and spread of drug-resistant malaria and proposed a mathematical model to improve the conceptual basis for policy decisions and which has implications for drug development as well as for malaria-control programmes.

TL;DR: The problem of drug resistance, discussed here by David Chapman, has provided impetus for the development of new approaches (such as vaccination) for the control of coccidiosis.

TL;DR: Vaccines, if intended as a means of parasite control, are unlikely to be generally successful if they do no more than mimic an immunological equilibrium that would be reached after natural exposure to the parasites.

TL;DR: Although trypanosomiasis is one of the most important parasitic diseases of domestic animals in China, little information on this disease has been published, so epidemiological studies of the past 40 years are reviewed.