Showing papers in "Parasitology Today in 1999"

TL;DR: A simple numerical approach to defining distribution of malaria transmission, based upon biological constraints of climate on parasite and vector development, provides a numerical basis for further refinement and prediction of the impact of climate change on transmission.

TL;DR: Kevin Lafferty focuses on evolutionary aspects that have not been fully explored of parasite increased trophic transmission, specifically how strong should PITT be and how might sexual selection and limb autotomy facilitate PITT.

TL;DR: The finding that the intracellular bacteria of filarial nematodes are related to the Wolbachia symbionts of arthropods has generated great interest and the potential role for these bacteria in filarial disease and as a target for chemotherapy is discussed.

TL;DR: The potential of albendazole as a macrofilaricide for treating individual patients with lymphatic filarial infections is emphasized as one of a number of important research questions that remain to be explored.

TL;DR: Sures et al. as mentioned in this paper discuss the phenomenon of conspicuous metal accumulation by parasites and how this might be applied to environmental monitoring, and suggest how environmental science and parasitology might profit from each other in the near future.

TL;DR: Rick Tarleton and Lei Zhang here consider an alternative view that the primary cause of chronic Chagas disease is the failure of the host to clear the infection, resulting in infection-induced, immune-mediated tissue damage.

TL;DR: The most recent advances in these two main approaches to the search for commercially viable molecular vaccines for parasitic nematodes are reviewed.

TL;DR: This veterinary experience is discussed, summarizing the progress made in understanding anthelmintic resistance and highlighting the tools available for research.

TL;DR: In this review, Christian Bogdan and Martin Röllinghoff summarize some of the more recently discovered mechanisms by which intracellular protozoan parasites manage to exploit macrophages as safe target cells.

TL;DR: In this review, Susan Welburn and Ian Maudlin chart the progress of trypanosomes through the fly and identify some of the hazards faced by both parasite and fly that affect vector competence of tsetse.

TL;DR: Human AE is rare but its potential high fatality rate, considerable costs of treatment and the persisting infection risk should be reasons for health authorities in European countries to establish coordinated systems of surveillance and risk assessment in combination with measures to reduce morbidity and mortality of AE in the human population.

TL;DR: How the application of molecular phylogenetics is helping to resolve some of the inconsistencies in morphological classification and phylogeny by establishing relationships between free-living and parasitic groups and showing possible patterns underlying the origins of parasitism is discussed.

TL;DR: These empirical approaches to probabilities of infection risk and epidemiological data on mortality provide a novel approach to present and projected burdens of malaria mortality, as discussed here by Bob Snow, Marlies Craig, Uwe Deichmann and Dave le Sueur.

TL;DR: Crucial questions remain about the true impact of tick-induced immunosuppression and the effect of immunity on the transmission oftick-borne diseases, despite some fascinating and important recent results, as discussed here by Peter Willadsen and Frans Jongejan.

TL;DR: Strategies for identifying candidate vaccine antigens of B. bovis and B. bigemina and for priming immune responses to evoke strain crossprotective immunity are reviewed.

TL;DR: The demography, pathology and clinical findings of toxoplasmic retinochoroiditis are reviewed, including mechanisms of retinal destruction and disease recurrences, and the local immunological response at this immune-privileged site are discussed.

TL;DR: Barrett and Fairlamb as mentioned in this paper investigated the mechanism underlying the cross-resistance between two major classes of drugs used in the treatment of African trypanosomiasis, the melaminophenyl arsenicals and diamidines.

TL;DR: The types of host traits that are modified by parasites are reviewed, some of the evolutionary consequences of parasite-induced alterations in host phenotypes are explored and some avenues for future research are suggested.

TL;DR: Recent progress in identifying how defined epitopes induce protective immunity and the role of antigenic variation in these epitopes as a mechanism of persistence are reviewed.

TL;DR: The current situation concerning the clinical and epidemiological aspects, immune response and diagnosis of human dirofilariases is reviewed, as has been shown by diagnosis using invasive methods for removing the nodules.

TL;DR: Clayton et al. as discussed by the authors highlighted the differences and similarities between the most commonly used model organisms, and assesses the relative advantages of different approaches and parasites for different types of investigation.

TL;DR: A number of energy-utilizing pumps and exchangers have been found in these organelles, which underlines their importance in the homeostasis of different elements, as discussed here by Roberto Docampo and Silvia Moreno.

TL;DR: The parasite GPI anchor structure and biosynthetic pathways are attractive targets for antimalarial and/or antiparasite drug development, as discussed here by Channe Gowda and Eugene Davidson.

TL;DR: The potential for chemotherapeutic exploitation of thiol metabolism in parasitic protozoa is reviewed by Luise Krauth-Siegel and Graham Coombs and provides thought-provoking ideas that will help direct future research.

TL;DR: Sunetra Gupta and Roy Anderson discuss how the balance between host immune responses against conserved and variable antigens shapes the population structure of pathogens.

TL;DR: The mechanisms that might be involved in the immunopathogenesis of Leishmania- HIV co-infection are examined.

TL;DR: Progress in reconstruction of trypanosome phylogeny based on molecular data from rRNA and protein-coding genes is reviewed, with a focus on protozoa.