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Showing papers in "Pharmacology & Therapeutics in 1979"








Journal ArticleDOI

107 citations










Journal ArticleDOI
TL;DR: Diamide sensitizes hypoxic cells synergistically with nitrofuran or nitroimidazole sensitizers, is effective against ascites tumors in vitro, and is useful for elucidating the mechanisms of aminothiol radioprotection.



Journal ArticleDOI
TL;DR: Ion transport phenomena have been reviewed and shown to be an integral part of many physiological processes in the nervous system including peripheral nerve, synaptic junctions and neuromuscular connections and to be of importance in determining the safety and acute and chronic toxicity of insecticides.

Journal ArticleDOI
TL;DR: It is unlikely that a carcinogenic effect will ever be demonstrated in man, but the information gained in uncovering industrial cancers could perhaps be used more profitably in determining risk of exposure to putative carcinogens.





Journal ArticleDOI
TL;DR: Radioimmunoassay of components of the renin-angiotensin system has enormously increased the number of published studies, but has left the fundamental problems still unresolved.

Journal ArticleDOI
TL;DR: There is increasing evidence from various types of studies that commonly prescribed drugs can interact with OCs (oral contraceptives), leading to a decreased contraceptive efficacy, and the effect of OCs on anticoagulant, antihypertensive, antidiabetic, and antidepressant drugs is outlined.

Journal ArticleDOI
TL;DR: The task of studying some actions of drugs on the morphology of parasites is undertaken, although this question is still scarcely touched on, although it is of great interest in the practical respect.

Journal ArticleDOI
TL;DR: It is demonstrated that the compounds tested cause a wide variety of pharmacodynamic effects in concentrations in which they are used as drug solvents in the laboratory and are recommended not to exceed the following concentrations in drug solutions for screening purpose.

Journal ArticleDOI
TL;DR: This review gives the reader a basis for understanding the controversy and included basic principles of photodynamic inactivation, medical aspects of herpesvirus infections, development of the therapeutic procedure, results of clinical studies, and results of in vitro studies which indicate potential long-term side effects.