Showing papers in "Progress in Lipid Research in 1981"

TL;DR: In the present communication the authors will discuss the following topics: further observation on the effects of the disease; effect of protein intake on the severity of the patients'; effect of fat exclusion on water exchange; effect on ovulation and reproduction; nature of the essential fatty acids.

TL;DR: The thesis is presented that foetal and infant development is normally protected by deposition of fat and other nutrient stores in the mother and the infant, in advance of requirements, which implies that measures for the prevention of low birth weight and malnutrition need to be implemented early in pregnancy, if not before.

TL;DR: Prostaglandins are intimately concerned in the atherogenic process via blood pressure regulation, platelet aggregation, vasospasm and smooth muscle proliferation and deserve greater attention in providing insight into lipid-induced atherogenesis and devising more rational preventive management.

TL;DR: The results imply that LCPE are not synthesized at maximal rates for several weeks after birth suggesting that placental transfer of LCPe is of primary importance in accretion of these fatty acids in the fetus.

TL;DR: A strong inverse correlation was found between progression of retinopathy and serum cholesteryl-linoleate and serum lipid responses were significant for the females, diet group II having the lowest levels and no differences were seen for the males.

TL;DR: This work investigated the formation of trienoic prostao glandins in three different systems: enzyme-limited, GSP-suppressed, and phenol-suppression, and found that in the presence of glutathione peroxidase (GSP) and its cosubstrate glutathion, the metabolism of eicosapentaenoic acid was depressed whereas that of arachidonic acid remained the same as in the absence of GSP.

TL;DR: This chapter summarizes some studies from this laboratory on polyenoic fatty acids in Retinal membranes, showing that they conform a highly dynamic pool because: (a) they are actively released from retinal membranes in vitro, and (b) they may be actively taken up into retinal lipids under the same conditions.

TL;DR: Essential fatty acids are shunted into an intracellular cholesteryl ester pool when the endothelium is injured and the consequences are enormous; smooth muscle cells proliferate and the atherosclerotic lesion develops.

TL;DR: The present experiments make use of AKR mice with implanted adipose tissue labeled with [1-14C]linoleic acid to address the question of how a growing tumor is able to derive the fatty acids necessary for membrane formation from the host tissues.

TL;DR: A substitution of EPA or possibly its precursor in the diet would be expected to lead to both an inhibition of arachidonic acid metabolism and the lowering of endogenous arachidonate in tissue (e.g., platelets) lipids.

TL;DR: The influence of increasing dietary levels of linoleate on clotting times and prostaglandin concentrations of rat serum and urine was evaluated and the lack of effect is discussed.