Showing papers in "Seminars in Arthritis and Rheumatism in 2000"

TL;DR: The initial presentation of Sjögren's syndrome determines subsequent outcome, and the overall mortality of patients with pSS compared with the general population is increased only in patients with adverse predictors.

TL;DR: The basal autonomic state of patients with FM is characterized by increased sympathetic and decreased parasympathetic tones, which may have implications regarding the symptomatology, physical and psychological aspects of health status.

TL;DR: Collagen hydrolysate is of interest as a therapeutic agent of potential utility in the treatment of osteoarthritis and osteoporosis, and its high level of safety makes it attractive as an agent for long-term use in these chronic disorders.

TL;DR: The cost template developed in this article can be used to estimate the likely costs of RA to society for industrialized countries and probably will underestimate indirect costs because of their incomplete coverage in the studies examined.

TL;DR: The main theme of this discussion will be that most (if not all) of these multisystem symptoms of FM could be explained on the basis of autonomic nervous system (ANS) dysfunction.

TL;DR: PMR with a normal ESR at diagnosis was infrequent in this study compared with previous studies, and ESR was a superior predictor of relapse than CRP, however, CRP was a more sensitive indicator of current disease activity.

TL;DR: Fn fragments can be functionally and biochemically characterized in diseased SF and modification of fragment formation and inhibition of fragment function may have potential therapeutic value in the interruption of chronic synovial inflammation.

TL;DR: Bisphosphonates have shown significant treatment benefit and are the agents of choice for both the treatment and prevention of corticosteroid-induced osteoporosis.

TL;DR: Sarcoidosis may be complicated by systemic vasculitis that can affect small- to large-caliber vessels and African American and Asian patients are disproportionately represented among cases with large vessel involvement.

TL;DR: The SAPHO syndrome may be underrecognized as the skin manifestations in patients were mild or absent, and optimal treatment for these patients remains unclear, it is important to make the diagnosis to avoid unnecessary investigations and treatment.

TL;DR: BD and FMF in patients with FMF-BD, and in patients suffering from each of these entities alone, are clinically and demographically comparable.

TL;DR: Although FMS is uncommon in men, its health outcome in the study population was worse than in women and further studies in larger samples and in diverse ethnocultural populations are needed to confirm this observation.

TL;DR: It may be wise to suspect a malignancy in men older than 40 years of age who develop HSP in the absence of a precipitating factor, and Epidemiological studies are needed to determine the association between adult HSP and malignancies.

TL;DR: A malignancy should always be excluded in children with musculoskeletal symptoms, especially when the clinical pattern is not characteristic of a specific rheumatic disease.

TL;DR: IVIg might be effective in treatment-resistant membranous or membranoproliferative lupus nephritis in patients who failed to respond to at least prednisone and cyclophosphamide.

TL;DR: The spectrum of HIV-associated rheumatic disease remains a diagnostic and therapeutic challenge for the clinician, and the impact of changes in HIV treatment on these disorders requires further assessment.

TL;DR: The severity of functional impairment as assessed by the SF-36, distinguishes patients with FMS and widespread pain alone from healthy individuals, and also discriminates between patients withidespread pain alone and FMS patients.

TL;DR: The clinical and immunopathogenetic similarities with classical rheumatologic diseases, the differential diagnosis with sarcoidosis and other inflammatory conditions, and the use of standard immunosuppressive medications make GCM a disease process that should be added to the rheumologist's expertise.

TL;DR: The potential for renal toxicity should always be considered when determining which DMARD to use for RA therapy, and DMARDs that combine efficacy with negligible renal adverse effects should be used for the treatment of patients susceptible to DMARD-associated renal damage.

TL;DR: Myalgia in children with FMF is common and can follow three different clinical patterns, which differ in the severity of pain, height of fever, and duration of the episode.

TL;DR: Very high frequency US is able to depict the anatomic substrate of distal phalanx involvement in several rheumatic diseases, adding useful information to clinical examination of the hand.

TL;DR: There is some evidence supporting an association between trauma and FM, but the evidence is not definitive and further prospective studies are needed to confirm this association and to identify whether trauma has a causal role.

TL;DR: Haluronan appears effective in relieving the pain of OA of the knee and provides a relatively safe alternative for patients for whom conventional therapy has failed.

TL;DR: To understand the expressed needs of physicians and their patients with respect to arthritis care, identify areas of agreement and disagreement in doctor and patient views, and to determine the types of educational programs needed, focus group interviews were conducted.

TL;DR: Anti-dsDNA antibodies may occur in patients with sarcoidosis, but their presence does not predict the subsequent development of SLE.

TL;DR: In Takayasu's arteritis, B-Mode US and EBCT was able to visualize the classical caliber abnormalities (stenosis, aneurysm) and, in contrast to angiography, to depict vessel wall thickening, a major pathologic feature of the disease.

TL;DR: Considerable evidence supports the positive effects of HA on joint cellular and immunologic function, however, further clinical studies are needed to determine whether these effects are valuable in altering the progression of OA.

TL;DR: In evaluation of spinal and SIJ abnormalities in many rheumatic diseases, MRI, in addition to PR, can replace conventional tomography, CT, and myelography and visualize soft tissue abnormalities and neurologic compromise without use of intrathecal contrast.

TL;DR: Serological evidence of past B19 infection is associated with the presence of cytopenia in patients with primary Sjögren's syndrome, and a possible relationship between B19 infected patients and the existence of cy topenia may occur in some patients immunologically or genetically predisposed.

TL;DR: CM and MM presenting in childhood or adulthood are infrequent; the symptoms are usually mild or moderate, and the prognosis generally is good, and in most patients the myopathy did not worsen, most remaining ambulatory.