Showing papers in "The American Journal of Medicine in 1983"

TL;DR: Application of practical diagnostic criteria for standard clinical use should assist in clinical management of nonspecific vaginitis and in further study of the microbiologic and biochemical correlates and the pathogenesis of this mild but quite prevalent disease.

TL;DR: It is concluded that there is a substantial risk of the development of renal failure in hospital and that the mortality rate due to hospital-acquired renal insufficiency remains high.

TL;DR: Animal experiments employing controlled degrees of cerebral ischemia have demonstrated that elevated blood-brain glucose concentrations greatly enhance the extent and degree of subsequent brain damage, and whether or not this relationship applies in man was examined by retrospectively segregating patients admitted with the diagnosis of ischemic stroke into diabetic and nondiabetic groups.

TL;DR: Spinal osteoporosis in men is frequently associated with recognizable risk factors, some of which are potentially remediable, and the risk associated with smoking and drinking increased with age.

TL;DR: Outcome predictions based on the strongest clinical predictors (age, sex, and serum creatinine level) were significantly enhanced by the addition of activity and chronicity indexes, and immunosuppressive agents appeared to provide a slight therapeutic advantage over oral corticosteroids alone.

TL;DR: Les pertes de tissu osseux trabeculaire ou cortical sont differentes, les manifestations cliniques aussi, and evidemment les facteurs etiologiques.

TL;DR: The capacity of the kidney to increase its level of function with protein intake suggests a renal function reserve, and in patients with a reduced number of nephrons, renal functional reserve may be diminished or absent.

TL;DR: It is concluded that autonomic nervous system function also declines with aging, but that other age-related changes such as a decline of baroreceptor sensitivity may lead to compensatory autonomics nervous system response, which could mask underlying functional defects.

TL;DR: The mean heart weight, frequency of atrial fibrillation, percentage of patients with heart failure, and frequency of myocardial infarction were increased in patients with cardiac amyloid, but these differences failed to reach statistical significance.

TL;DR: Electrocardiographic left ventricular hypertrophy with repolarization criteria more than doubles the risk of hypertension alone and carries a greater risk of cardiovascular morbidity and mortality than cardiac enlargement, and is a harbinger of serious cardiovascular disease.

TL;DR: It is concluded that hyperzincuria, resulting from a glucose-mediated process that is not osmotic, interacts with impaired zinc absorption to produce zinc deficiency in patients with type II diabetes mellitus.

TL;DR: Clinical characteristics examined in 3,627 consecutive, symptomatic patients referred for cardiac catheterization between 1969 and 1979 found to be important for estimating the likelihood a patient had significant coronary artery disease accurately estimated the likelihood of disease.

TL;DR: A regular program of physical activity is very likely to improve glucose tolerance through an enhancement of insulin sensitivity and the newer generation sulfonylurea agents appear to provide a promising means of improving the insulin resistance.

TL;DR: In view of its potential value to both clinicians and microbiologists, pyuria should be accurately determined and expressed as cells per cubic millimeter in uncentrifuged urine.

TL;DR: Tissue distributions are qualitatively similar for both drugs in albino rats--namely, bone, fat, and brain less than muscle less than eye less than heart less than kidney less than liver less than lung less than spleen less than adrenal--but the absolute distribution values are about 2.5 times higher for chloroquine.

TL;DR: Researchers studied erythrocyte G unit activity and clinical endocrine function in 29 patients with pseudohypoparathyroidism type I to test the hypothesis that a defective G unit should lead to resistance to multiple hormones that act by stimulating adenylate cyclase.

TL;DR: A syndrome that mimicked malignant histiocytosis clinically and pathologically developed as a terminal event and a likely mechanism for this syndrome is the production of lymphokines (macrophage-activating factors) by neoplastic T lymphocytes.

TL;DR: Findings indicate that specific noninvasive studies are helpful in assessing the likelihood of normal or definitely elevated pulmonary artery pressures in patients with progressive systemic sclerosis, but patients with mild pulmonary hypertension are not likely to be identified by these nonin invasive studies.

TL;DR: Results indicate a wider clinical spectrum in primary aldosteronism than previously described and show that nonsuppressible aldosterone production is its most important diagnostic hallmark and the single best diagnostic screening procedure, and that adrenal venous sampling for plasma ald testosterone concentration remains the most precise technique for identification and localization of tumors.

TL;DR: The results provide objective documentation of the time course over which administration of parenteral corticosteroids speeds the recovery of asthmatic patients who are unresponsive to standard therapy.

TL;DR: It is indicated that increased adiposity in women is an important long-term factor for significant pulmonary embolism at autopsy, which raises the possibility that weight reduction in obese women may decrease the chances of pulmonary emblism.

TL;DR: Sustained clinical remission was induced in all four patients with a regimen of daily cyclophosphamide and alternate-day prednisone therapy, considered the treatment of choice in severe, progressive, or corticosteroid-resistant isolated angiitis of the central nervous system.

TL;DR: No eye disease was detected in over 900 rheumatoid arthritis patients treated with chloroquine or less than 6.5 mg/kg per day of hydroxychloroquine for a mean of about seven years, and these dosage rates are safe, since they are below the threshold of retinal toxicity.

TL;DR: Type II mesangiocapillary glomerulonephritis was more common in children than in adults, but no other clinical feature distinguished the two types at onset, and patients with type II had lower serum C3 concentrations and more frequently showed C3-splitting activity in the serum.

TL;DR: Obesity may mitigate the effects of chronically elevated total peripheral resistance (and therefore end-organ damage) in essential hypertension, thereby gently enhancing the long-term risk of congestive failure.

TL;DR: It appears that methotrexate is approximately as effective as intramuscular gold and D-penicillamine but that it has a quicker onset of response and less serious toxicity.

TL;DR: Echocardiography was a useful and, at times, essential part of the evaluation of these patients with the congestive heart failure syndrome and recommended management after echOCardiography changed in all 18 patients.

TL;DR: The presence of a mural thrombus can be accurately identified in patients with acute myocardial infarction and predicted in a subgroup of those patients who should be considered for anticoagulation to prevent systemic embolization and followed with serial two-dimensional echocardiography.

TL;DR: In this article, the rate of change of the 51Cr-EDTA glomerular filtration rate was measured in 13 patients with insulin-dependent diabetes and diabetic nephropathy for up to 51 months.

TL;DR: Verbal expressions of frequency should be eliminated from medical communications; failing that, the author should specify numerically the frequency he intends when he uses any such expression.