Showing papers in "Transfusion in 2012"

TL;DR: This work assessed the safety of transfused older versus newer stored blood, finding that older blood develops lesions and accumulates potentially injurious substances while newer blood is stored for up to 42 days.

TL;DR: The pathogenesis, diagnosis, and management of the risks associated with plasma transfusion, and the effects of pathogen inactivation or reduction methods on these risks are discussed.

TL;DR: This is an update that includes all new RCTs published since the original review of randomized controlled trials (RCTs) revealed a lack of evidence that supported the efficacy of FP use.

TL;DR: The effects of blood donation intensity on iron and hemoglobin (Hb) in a prospective study is evaluated and it is shown that blood donors are at risk of iron deficiency.

TL;DR: The rate of TACO caused by plasma transfusion was sought to determine to determine the rate of transfusion-related mortality reported to the Food and Drug Administration.

TL;DR: Blood donations were tested for dengue virus (DENV) RNA and recipients of RNA‐positive donations traced to assess transfusion transmission and no new cases were reported in Puerto Rico in 2007.

TL;DR: In this article, the authors presented an evaluation of the reliability of routine antenatal fetal RHD screening in D-, pregnant women to ascertain the requirement for antenatal RhD prophylaxis.

TL;DR: The goal of this comprehensive, sequential review is to update these components to include those now available (February 2012) as well as to explore cost and regulatory factors that impact the development and use of these materials.

TL;DR: Screening US blood donors for Trypanosoma cruzi infection is identifying autochthonous, chronic infections and the burden of and describe putative risk factors for vector‐borne infection in the United States is evaluated.

TL;DR: The assessment of whole blood coagulation using rotation thromboelastometry (ROTEM) was compared to coagulating tests routinely performed during cardiac surgery.

TL;DR: Using constructs from the Theory of Planned Behavior and theories of altruism, this article explores how multiple motivations and beliefs for blood donation are clustered and change across the donor career.

TL;DR: It is hypothesized that an MTP would improve outcomes in children, through a balanced blood product resuscitation, through the balanced transfusion support protocols for pediatric trauma patients.

TL;DR: The efficacy of sialylation compared to nonsialylated IVIg for the ability to attenuate immune thrombocytopenia (ITP) in a mouse model that approximates the clinical setting of human ITP is examined.

TL;DR: A prospective study is designed to test the hypothesis that integrating TEG into the MTP would facilitate goal‐directed therapy and provide equivalent outcomes compared to conventional coagulation testing.

TL;DR: Clinical findings with pathogen‐reduced plasma have provided an impetus to the US Food and Drug Administration to promulgate specific requirements for approval of novel plasma products, some of which may be too burdensome for the industry to readily overcome.

TL;DR: Intraoperative blood salvage is a technique that is frequently used in major blood loss surgery and is avoided during cancer surgery where a fear exists of entraining cancer cells into the shed blood.

TL;DR: The challenge for treating and laboratory‐based physicians is to understand the contributory role(s) of each of these syndromes, so that the potential value of emerging and innovative pharmacologic strategies can be considered as options in patient blood management.

TL;DR: This study aimed at assessing the value of TEM in monitoring blood coagulation and guide transfusion support in OLT.

TL;DR: Red blood cell storage systems have been licensed in the United States based on the demonstration that 24‐hour in vivo recovery was greater than 75% and hemolysis was less than 1%.

TL;DR: To assess the extent of infection and the safety of donated blood, local blood donations were tested for presence of Coxiella burnetii antibodies and DNA.

TL;DR: A systematic review of the literature to estimate the cost of a 2‐unit red blood cell (RBC) transfusion in Western Europe shows that blood is a costly and scarce resource.

TL;DR: In this paper, age and sex-specific donation and demand rates for blood supply based on 2008 data and project demand between 2008 and 2036 based on these rates and using population data from the Ontario Ministry of Finance.

TL;DR: The prediction that blood donors will be motivated in general by warm glow was compared to predictions from other theoretical models: strong reciprocity and empathy.

TL;DR: The overall risk of hemolytic transfusion reactions (HTRs) from plasma (minor)‐incompatible platelet (PLT) transfusions and the role of a critical anti‐A or anti‐B titer in predicting and preventing these reactions has not been clearly established.

TL;DR: The objective was to assess the efficacy and safety of splenectomy and cyclophosphamide as salvage therapies in severeThrombotic thrombocytopenic purpura (TTP).

TL;DR: A territory‐wide study has been performed to look at its prevalence among Chinese thalassemia major patients and found that red blood cell alloimmunization is reported to occur at an incidence of 5.2% to 23.5% among patients with thalassesmia requiring chronic transfusion.

TL;DR: Blood operators have taken measures to reduce transfusion‐related acute lung injury (TRALI) and the impact of TRALI reduction measures has been assessed.

TL;DR: C1‐esterase inhibitor replacement therapy is the treatment of choice for acute edema attacks in patients with hereditary angioedema (HAE).

TL;DR: Blood operations are constrained by many limitations in combat settings and there are many challenges that require innovative solutions, so innovative solutions are needed.

TL;DR: Over 4 years, 149 hepatitis’B surface antigen–negative acute‐phase HBV NAT–positive donations were identified and the lookback program identified one probable HBV transmission.