Journal ArticleDOI
246 - Electric breakdown of bilayer lipid membranes I. The main experimental facts and their qualitative discussion
I.G. Abiror,V.B. Arakelyan,L.V. Chernomordik,Yu.A. Chizmadzhev,V. F. Pastushenko,M.R. Tarasevich +5 more
TLDR
In this paper, a qualitative interpretation of the breakdown phenomenon is proposed, which is based upon the concept of structural defects of the type of throughgoing pores, whose development is favored by the electric field.About:
This article is published in Bioelectrochemistry and Bioenergetics.The article was published on 1979-01-01. It has received 515 citations till now. The article focuses on the topics: Membrane & Biological membrane.read more
Citations
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Theory of electroporation: A review
TL;DR: This review of the essential features of theoretical models of electroporation focuses on transient aqueous pore models, which can account for key features of mechanical instability and dramatic reversible electrical behavior of certain planar membranes and of cell membranes, and some features of molecular transport.
Journal ArticleDOI
Protein-lipid interplay in fusion and fission of biological membranes.
TL;DR: The phenomenology and the pathways of the well-characterized reactions of biological remodeling, such as fusion mediated by influenza hemagglutinin, are compared with those studied for protein-free bilayers and some proteins involved in fusion and fission are considered.
Book ChapterDOI
Electrical breakdown, electropermeabilization and electrofusion
TL;DR: The techniques for electrical breakdown, electropermeabilization and electrofusion could be an important tool in this process, since the high electrical fields occurring naturally in the membrane play an important role in the selective transport of substances across the membrane as well as in natural regulatory processes.
Journal ArticleDOI
Electroporation: A general phenomenon for manipulating cells and tissues
TL;DR: Electroporation of isolated cells has also been used for introduction of enzymes, antibodies, and other biochemical reagents for intracellular assays, and more recently, tissue electroporation has begun to be explored, with potential applications including enhanced cancer tumor chemotherapy, gene therapy, transdermal drug delivery, and noninvasive sampling for biochemical measurement.
References
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Journal ArticleDOI
Electrical breakdown of bimolecular lipid membranes as an electromechanical instability.
TL;DR: The bimolecular lipid membrane is modeled as a bulk elastic layer subject to a compressive electric force caused by applied voltages that tends to crush the film and thus rupture it and the predicted breakdown voltage shows fair agreement.
Journal ArticleDOI
Changes in end-plate activity produced by pre-synaptic polarization
J. del Castillo,Bernard Katz +1 more
TL;DR: By passing polarizing currents through the terminal portion of a motor axon and studying their effects from the other side of the synapse, it was hoped to get further information on the neuromuscular mechanism.
Journal ArticleDOI
Ion-membrane interactions as structural forces.
TL;DR: The magnitude of the electric stress on the membrane faces is illustrated and some results for the electrostatic interaction between an ion and different forms of membrane defects created by peptides that facilitate transport are reviewed.
Journal ArticleDOI
Electrohydrodynamic instability in plane layers of fluid
D. H. Michael,M. E. O'Neill +1 more
TL;DR: In this article, the instability of a plane layer of nonconducting fluid which is in hydrostatic equilibrium between two semi-infinite conducting fluids with surface charges is discussed for both inviscid and viscous fluid models.
Journal ArticleDOI
Dielectric breakdowm in the membranes of itValonia utricularis. The role of energy dissipation
TL;DR: The electrical properties of the membranes of Valonia utricularis were investigated and it was found that at a critical membrane potential difference of 0.85 V there was a large and discontinuous decrease in the membrane impedance and the slope resistance beyond this potential was virtually zero.