Book ChapterDOI
53 – Synovial Fluid Analyses, Synovial Biopsy, and Synovial Pathology
Hani El-Gabalawy
- pp 753-769
About:
The article was published on 2013-01-01. It has received 3 citations till now. The article focuses on the topics: Synovial fluid.read more
Citations
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Journal ArticleDOI
Evaluation of antigen-induced synovitis in a porcine model: Immunological, arthroscopic and kinetic studies.
Francisco-Javier Vela,F. Sanchez-Margallo,Rebeca Blázquez,Verónica Álvarez,Raquel Tarazona,M. Teresa Mangas-Ballester,Alejandro Cristo,Javier G. Casado +7 more
TL;DR: An animal model of antigen-induced synovitis to be used in the evaluation of anti-inflammatory therapies and the identification of IL-12p40 and T cell subsets as immune biomarkers is described.
OtherDOI
Sample Preparation for LC‐MS Bioanalysis of Urine, Cerebrospinal Fluid, Synovial Fluid, Sweat, Tears, and Aqueous Humor Samples
Journal ArticleDOI
Mechanical adaptation of synoviocytes A and B to immobilization and remobilization: a study in the rat knee flexion model
TL;DR: Knee immobilization and remobilization significantly modulated synoviocytes in vivo, stressing their mechanosensitive nature and possible contribution to immobility-induced changes of the joint capsule.
References
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Journal ArticleDOI
Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium.
Martine Chabaud,Jean Marc Durand,Nicolas Buchs,François Fossiez,Guillaume Page,Lucien Frappart,Pierre Miossec +6 more
TL;DR: It is indicated that IL-17 contributes to the active, proinflammatory pattern that is characteristic of RA through the contribution of some Th1-like T cells appear to mediate synovial inflammation.
Journal ArticleDOI
Synovial tissue in rheumatoid arthritis is a source of osteoclast differentiation factor
Ellen M. Gravallese,Cathy Manning,Alfie Tsay,Akifumi Naito,Chin Pan,Edward P. Amento,Steven R. Goldring +6 more
TL;DR: These studies address the potential role of ODF and the bone and marrow microenvironment in the pathogenesis of osteoclast-mediated bone erosion in RA and identify TRAP-positive, cathepsin K-positive osteOClast precursor cells are identified in areas of pannus invasion into bone in RA.
Journal ArticleDOI
Macrophages in rheumatoid arthritis
TL;DR: Selective counteraction of macrophage activation remains an efficacious approach to diminish local and systemic inflammation, as well as to prevent irreversible joint damage.
Journal ArticleDOI
The major synovial targets of the rheumatoid arthritis-specific antifilaggrin autoantibodies are deiminated forms of the alpha- and beta-chains of fibrin.
C Masson-Bessière,Mireille Sebbag,Elisabeth Girbal-Neuhauser,Leonor Nogueira,Christian Vincent,Tatsuo Senshu,Guy Serre +6 more
TL;DR: Results show that deiminated forms of fibrin deposited in the rheumatoid synovial membranes are the major target of AFA, and suggest that autoimmunization against deimination fibrIn is a critical step in RA pathogenesis.
Journal ArticleDOI
Oxidation in rheumatoid arthritis
TL;DR: Repetitive cycles of hypoxia and reoxygenation associated with changes in synovial perfusion are postulated to activate Hypoxia-inducible factor-1α and nuclear factor-κB, two key transcription factors that are regulated by changes in cellular oxygenation and cytokine stimulation, and that orchestrate the expression of a spectrum of genes critical to the persistence of synovitis.