Book ChapterDOI
84 – Surfactant Treatment
Alan H. Jobe,Suhas G. Kallapur +1 more
- pp 831-842
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The article was published on 2017-01-01. It has received 1 citations till now. The article focuses on the topics: Pulmonary surfactant.read more
Citations
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Journal ArticleDOI
A multicenter randomized, placebo-controlled trial of surfactant therapy for respiratory distress syndrome
Jeffrey D. Horbar,Roger F. Soll,J. M. Sutherland,U. Kotagal,Ags Philip,D. L. Kessler,George A. Little,William H. Edwards,D. Vidyasagar,Tnk Raju,Alan H. Jobe,M. Ikegami,Mullet,D. Z. Myerberg,Timothy L. McAuliffe,Jerold F. Lucey +15 more
TL;DR: Treatment with the single-dose surfactant regimen used in this study reduces the severity of respiratory distress during the 72 hours after treatment and decreases the frequency of pneumothorax, but that it does not significantly improve clinical status later in the neonatal period and does not reduce neonatal mortality.
References
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Journal ArticleDOI
Artificial surfactant therapy in hyaline-membrane disease
TL;DR: Ten preterm infants severely ill with hyaline-membrane disease were given artificial surfactant endotracheally and eight survived, including five of six with birthweight less than 1500 g; two died of unrelated causes.
Journal ArticleDOI
Pulmonary surfactant therapy.
TL;DR: In 1959, not long after surfactant had been identified as critical to maintaining lung inflation at low transpulmonary pressures, saline extracts from the lungs of preterm infants with respiratory distress syndrome lacked the low surface tension characteristic of pulmonary Surfactant.
Journal ArticleDOI
Properties, function and origin of the alveolar lining layer.
TL;DR: Equally stable foam is found in the bronchi of an animal the respiratory movements of which have been paralysed and into the trachea of which a mixture of oxygen and ammonia gas has been insufflated for one or two hours.
Journal ArticleDOI
Impact of a physiologic definition on bronchopulmonary dysplasia rates.
Michele C. Walsh,Qing Yao,Patricia A Gettner,Ellen C. Hale,Monica V. Collins,Angelita Hensman,Ruth Everette,Nancy Peters,Nancy A. Miller,Gerry Muran,Kathy J. Auten,Nancy S. Newman,Gina Rowan,Cathy Grisby,Kathy Arnell,Lucy Miller,Bethany Ball,Georgia E. McDavid +17 more
TL;DR: The physiologic definition of BPD facilitates the measurement of B PD as an outcome in clinical trials and the comparison between and within centers over time, and reduced the variation among centers.
Journal ArticleDOI
Early surfactant administration with brief ventilation vs. selective surfactant and continued mechanical ventilation for preterm infants with or at risk for respiratory distress syndrome.
TL;DR: Two treatment strategies in preterm infants with, or at risk for, RDS are compared: early surfactant administration with brief mechanical ventilation (less than one hour) followed by extubation, vs later, selective surfactants administration, continued mechanical ventilation andextubation from low respiratory support.