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A Case of Disseminated Mycobacterium avium Infection in a Dog in Greece

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TLDR
Cytology of fine-needle-aspiration material, obtained from popliteal lymph node, revealed macrophages with intracytoplasmic, nonstaining, slender, rod-like structures, indicative of mycobacteria.
Abstract
A Basset Hound dog was presented with anorexia, fever, diarrhea, significant level of splenomegaly, and enlargement of mesenteric and superficial lymph nodes. Cytology of fine-needle-aspiration material, obtained from popliteal lymph node, revealed macrophages with intracytoplasmic, nonstaining, slender, rod-like structures, indicative of mycobacteria. Bacterial culture of lymph node aspirated material produced a colony which by means of molecular techniques (PCR amplification and hybridization of PCR products) was subsequently identified as Mycobacterium avium. This is the first report of disseminated M. avium infection in a dog in Greece.

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Journal ArticleDOI

Applying the One Health Concept to Mycobacterial Research - Overcoming Parochialism.

TL;DR: In this article, a comprehensive review of the zoonotic aspect of mycobacteria in the context of the One Health initiative is provided, with the purpose of providing a concise and comprehensive resource.
Journal ArticleDOI

Mycobacterium avium: an Emerging Pathogen for Dog Breeds with Hereditary Immunodeficiencies

TL;DR: The collaborative efforts by microbiologists, veterinary clinicians, dog breeders, primary care physicians, and infectious disease specialists applying the One Health approach are crucial for the best management and prevention of MAC infection.
Journal ArticleDOI

Molecular characterization and drug susceptibility profile of a Mycobacterium avium subspecies avium isolate from a dog with disseminated infection.

TL;DR: The molecularly identified the MAC pathogen and its drug susceptibility profile in a relatively short period of time (7 days) and characterized new genetic mutations likely to have been involved in the observed ethambutol resistance.
Journal ArticleDOI

Unusual presentation of canine Mycobacterium avium infection.

TL;DR: To the authors’ knowledge this is the first documented case of canine M avium infection that presented with a cutaneous lesion but no systemic clinical signs and highlights that in cases of cutaneous histiocytic infiltrate in dogs mycobacterial infection should remain a differential diagnosis, even in the absence of suggestive organisms on histopathological examination.
Journal ArticleDOI

The Mycobacterium avium complex – an underestimated threat to humans and animals

TL;DR: There is clearly a need for further research into the virulence factors associated with MAC bacteria, and further studies should also examine the role of MAP in the etiopathogenesis of Crohn's disease.
References
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Journal ArticleDOI

Zoonotic aspects of Mycobacterium bovis and Mycobacterium avium-intracellulare complex (MAC)

TL;DR: This review examines the possible reservoirs of these pathogens in the environment and in wildlife, their role as sources of infection in humans and animals and their health impact on humans.
Journal ArticleDOI

Epidemiology of selected mycobacteria that infect humans and other animals.

TL;DR: Clinical and diagnostic issues are discussed and related to estimates of the incidence and prevalence of these diseases among humans, and source of infection, route of transmission and control measures are presented.
Journal ArticleDOI

Fine needle aspiration cytology of suspected tuberculous lymphadenitis.

TL;DR: Fine needle aspiration cytology of suspected tuberculous lymphadenitis is described as "highly suggestive" of leukaemia and the use of chemotherapy to correct for this condition is recommended.
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Mycobacterium avium and Mycobacterium intracellulare infection in mammals.

TL;DR: The potential zoonotic importance of M. avium infections has been indicated, but requires clarification.
Journal ArticleDOI

Mycobacterium avium subsp. hominissuis Infection in 2 Pet Dogs, Germany

TL;DR: The report concerns 2 young dogs, a 3-year-old miniature schnauzer and a 1- year-old Yorkshire terrier, that lived in different geographic regions in Germany and were euthanized after a final phase of diarrhea.
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