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Proceedings ArticleDOI

A non-invasive spectral reflectance method for mapping blood oxygen saturation in wounds

L. Martinez
- pp 112-116
TLDR
It is shown that reflectance measurements can be used to determine the amount of blood O/sub 2/ saturation of a wound, and an algorithm designed to calculate the blood oxygen saturation from narrow band reflectance images at 760 and 800 nm was used.
Abstract
Reflectance spectroscopy is a common technique used to analyze blood oxygen saturation in biological tissues. This study describes a non-invasive method for mapping blood oxygen saturation in wounds using reflectance measurements obtained from a hyperspectral imaging system. The maps illustrate changes in blood oxygen saturation with high spatial resolution. This allows observation into local blood oxygen supplies of tissue as opposed to common point measurement techniques such as pulse oximetry and optical fiber probing. To demonstrate this, an algorithm designed to calculate the blood oxygen saturation from narrow band reflectance images at 760 and 800 nm was used. The algorithm incorporates the contributions of absorption by oxy-(HbO/sub 2/) and deoxy-hemoglobin (Hb) at the oxygen (O/sub 2/) sensitive and O/sub 2/ insensitive wavelength. Results of the algorithms performance are presented to demonstrate that reflectance measurements can be used to determine the amount of blood O/sub 2/ saturation of a wound.

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Citations
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Journal ArticleDOI

Review of spectral imaging technology in biomedical engineering: achievements and challenges

TL;DR: This review introduces the basics of spectral imaging, imaging methods, current equipment, and recent advances in biomedical applications and highlights the benefits and development trends of biomedical spectral imaging.
Patent

Hyperspectral imaging in diabetes and peripheral vascular disease

TL;DR: In this article, the authors present methods and systems of hyperspectral and multispectral imaging of medical tissues for the detection and evaluation of diseases and disorders such as, but not limited to diabetes and peripheral vascular disease.
Patent

Medical hyperspectral imaging for evaluation of tissue and tumor

TL;DR: In this article, the authors present an approach and methods for hyperspectral imaging analysis that assists in real and near-real time assessment of biological tissue condition, viability, and type, and monitoring the above over time.
Journal ArticleDOI

Polarization-Sensitive Hyperspectral Imaging in vivo : A Multimode Dermoscope for Skin Analysis

TL;DR: A multimode dermoscope that combines polarization and hyperspectral imaging with an efficient analytical model to map the distribution of specific skin bio-molecules is developed, correcting for the melanin-hemoglobin misestimation common to other systems, without resorting to complex and computationally intensive tissue optical models.
Patent

Hyperspectral technology for assessing and treating diabetic foot and tissue disease

TL;DR: In this article, an index map comprising both pressure and perfusion information from a diabetic patient foot for the purpose of treatment is presented. But the index map may also be a map of perfusion and metabolism of the tissue (reflecting oxygen delivery and oxygen extraction, obtained by thermal imaging, hyperspectral imaging, or duplex ultrasound, MRA, CT or laser Doppler imaging).
References
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Book

Medical instrumentation: Application and design

TL;DR: Basic Concepts of Medical Instrumentation (W. Olson).
Journal Article

Skin optics

TL;DR: The absorption and scattering data show that for all wavelengths considered, scattering is much more important than absorption, and any quantitative dosimetry for skin treated with (laser) light is inaccurate.
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