Journal ArticleDOI
A piscine glutathione S-transferase which efficiently conjugates the end-products of lipid peroxidation
TLDR
Fish are relatively rich in polyunsaturated fatty acids and thus GSTA mediated conjugation may be an important mechanism for detoxifying peroxidised lipid breakdown products.About:
This article is published in Marine Environmental Research.The article was published on 1998-07-01. It has received 156 citations till now. The article focuses on the topics: Glutathione S-transferase & Lipid peroxidation.read more
Citations
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Journal ArticleDOI
Contaminant-stimulated reactive oxygen species production and oxidative damage in aquatic organisms
Journal ArticleDOI
Tissue-specific oxidative stress responses in fish exposed to 2,4-D and azinphosmethyl.
TL;DR: The results show that SOD activity in gill and GST activity in kidney may be used as biomarkers for pollution monitoring and indicate that the activities of certain biomarkers in C. carpio are more sensitive to pesticides than those in O. niloticus.
Journal ArticleDOI
Analytical methods for determining metabolites of polycyclic aromatic hydrocarbon (PAH) pollutants in fish bile. A Review.
TL;DR: The state-of-the-art for these different analytical methods is presented and the advantages and limitations of each approach as well as aspects related to analytical quality control and inter-laboratory comparability of data and availability of certified reference materials are discussed.
Journal ArticleDOI
Comparative study of the antioxidant and reactive oxygen species scavenging properties in the extracts of the fruits of Terminalia chebula, Terminalia belerica and Emblica officinalis
TL;DR: The in vitro antioxidant and reactive oxygen species scavenging activities of Terminalia chebula, Terminalia belerica and Emblica officinalis fruit extracts showed quite good efficacy in their antioxidant and radical scavenging abilities, compared to the standards.
References
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Journal ArticleDOI
The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance.
John D. Hayes,David J. Pulford +1 more
TL;DR: The biochemical functions of GST are described to show how individual isoenzymes contribute to resistance to carcinogens, antitumor drugs, environmental pollutants, and products of oxidative stress, and to allow identification of factors that may modulate resistance to specific noxious chemicals.
Book ChapterDOI
Assays for differentiation of glutathione S-transferases.
TL;DR: This chapter provides the spectrophotometric, titrimetric, nitrite, and cyanide assay for the differentiation of glutathione S-transferases.
Journal ArticleDOI
Glutathione transferases--structure and catalytic activity.
Bengt Mannervik,U H Danielson +1 more
TL;DR: The glutathione transferases are recognized as important catalysts in the biotransformation of xenobiotics, including drugs as well as environmental pollutants, and numerous transferases from mammalian tissues, insects, and plants have been isolated and characterized.
Journal ArticleDOI
The peroxisome proliferator activated receptors (PPARs) and their effects on lipid metabolism and adipocyte differentiation
TL;DR: In rodents, a PPAR alpha-mediated change in the expression of genes involved in fatty acid metabolism lies at the basis of the phenomenon of peroxisome proliferation, a pleiotropic cellular response, mainly limited to liver and kidney and which can lead to hepatocarcinogenesis.
Journal ArticleDOI
Separation and characterization of the aldehydic products of lipid peroxidation stimulated by ADP-Fe2+ in rat liver microsomes.
TL;DR: It is concluded that considerable amounts of biologically reactive carbonyl derivatives are released in lipid peroxidation and yet may not be picked up by the thiobarbituric acid reaction.
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