Journal ArticleDOI
A silicon-based protecting group for the αβ-unsaturation of αβ-unsaturated ketones
David J. Ager,Ian Fleming +1 more
TLDR
Silyl-lithium reagents add to the β-position of αβ-unsaturated enones in the presence of copper(I) iodide, and the enone can be regenerated by treatment with copper(II) bromide.Abstract:
Silyl-lithium reagents add to the β-position of αβ-unsaturated enones in the presence of copper(I) iodide, and the enone can be regenerated by treatment with copper(II) bromide.read more
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Journal ArticleDOI
Silicon derivatives of the metals of groups 1 and 2
Paul D. Lickiss,Colin M. Smith +1 more
TL;DR: An account of the syntheses, structures and reactions of compounds containing group 1 or 2 elements bonded to silicon is given in this article, focusing mainly on the group 1 derivatives as these are far more numerous than those of the group 2 elements.
Journal ArticleDOI
Cu(I)–NHC Catalyzed Asymmetric Silyl Transfer to Unsaturated Lactams and Amides
TL;DR: The first asymmetric silylation of unsaturated lactams and amides using Cu(I)-NHC catalysts and PhMe2SiBpin has been accomplished and the method has been exploited in an expedient asymmetric synthesis of the (R)-enantiomer of the nootropic drug oxiracetam.
Book ChapterDOI
Some Aspects of Silicon-Transition Metal Chemistry
TL;DR: In this article, the authors discuss the aspects of silicon-transition-metal chemistry and discuss the most important synthetic routes for the elimination of an alkali halide between the salt of a transition-metal anion and a silicon halide.
Journal ArticleDOI
Silicon‐ and Tin‐Based Cuprates: Now Catalytic in Copper!
TL;DR: These efforts towards copper(I)-catalyzed carbon--silicon and also carbon--tin bond formations are described using soft bis(triorganosilyl) and bis( triorganostannyl) zinc reagents as powerful sources of nucleophilic silicon and tin.
Journal ArticleDOI
Copper-Catalyzed Carbon–Silicon Bond Formation
TL;DR: In organic synthesis, organosilanes have become a mainstay in organic synthesis as they can participate in a wide number of reactions where they act as a soft carbon nucleophile as mentioned in this paper.