Journal ArticleDOI
A technique for using CT images in attenuation correction and quantification in SPECT.
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TLDR
The value of performing scatter correction prior to attenuation correction in obtaining accurate quantification is demonstrated and the practicalities of applying the technique in patient studies are discussed.Abstract:
A technique is described for using computed tomography (CT) images for attenuation correction and quantification in SPECT. The CT images are aligned with the corresponding SPECT slices and the Hounsfield units are converted to linear attenuation coefficient values for the SPECT radionuclide. The attenuation coefficient map thus produced is used to provide the attenuation correction required in the SPECT reconstruction. The technique has been evaluated in both a non-anatomical and an anatomical phantom giving a mean accuracy in quantifying activity of various features in the phantoms of 2.6% (range 0.3%-4.0%). The value of performing scatter correction prior to attenuation correction in obtaining accurate quantification is demonstrated. The practicalities of applying the technique in patient studies are discussed.read more
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Journal ArticleDOI
X-ray-based attenuation correction for positron emission tomography/computed tomography scanners.
TL;DR: A synergy of positron emission tomography (PET) scanners is the use of the CT data for x-ray-based attenuation correction of the PET emission data, which has other advantages, including a lack of bias introduced from post-injection transmission scanning, which is an important practical consideration for clinical scanners, as well as reduced scan times.
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Determination of the Attenuation Map in Emission Tomography
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TL;DR: The physical and methodologic basis of attenuation correction is presented and recent developments in algorithms used to compute the attenuation map in ECT are summarized.
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Multicenter Clinical Trial to Evaluate the Efficacy of Correction for Photon Attenuation and Scatter in SPECT Myocardial Perfusion Imaging
Robert C. Hendel,Daniel S. Berman,S. James Cullom,William P. Follansbee,Gary V. Heller,Hosen Kiat,Mark W. Groch,John J. Mahmarian +7 more
TL;DR: Significant improvements in the normalcy rate were noted without a decline in overall sensitivity but with a reduction in detection of extensive coronary disease, and regional differences were also noted.
Journal ArticleDOI
Registration of MR and CT images for skull base surgery using point-like anatomical features.
Derek L. G. Hill,David J. Hawkes,J. E. Crossman,Michael Gleeson,Tim C. S. Cox,E. E. C. M. L Bracey,Anthony J. Strong,P. E. Graves +7 more
TL;DR: A registration technique for combining magnetic resonance imaging (MRI) and computed tomography (CT) images of the skull base for use in surgical planning based on user identification of point-like landmarks visible in both modalities is developed.
Journal ArticleDOI
Gamma camera-mounted anatomical X-ray tomography: technology, system characteristics and first images
TL;DR: Despite limitations of the system when compared with a state of the art CT scanner, the transmission anatomical maps allow for precise anatomical localisation and for attenuation correction of the emission images.