Journal ArticleDOI
A Virtual Instrument for Automated Measurement of Arterial Compliance
Jayaraj Joseph,V. Jayashankar +1 more
TLDR
A simple instrument for noninvasive in vivo evaluation of arterial compliance using a single element ultrasound transducer that can measure arterial distension with a precision better than 5 and the end-diastolic arterial diameter with an accuracy of 1%.Abstract:
Measurement of arterial distensibility is very important in cardiovascular diagnosis for early detection of coronary heart disease and possible prediction of future cardiac events. Conventionally, B-mode ultrasound imaging systems have been used along with expensive vessel wall tracking systems for estimation of arterial distension and calculation of various estimates of compliance. We present a simple instrument for noninvasive in vivo evaluation of arterial compliance using a single element ultrasound transducer. The measurement methodology is initially validated using a proof of concept pilot experiment using a commercial ultrasound pulser-receiver. A prototype system is then developed around a PXI chassis using LABVIEW software. The virtual instrument employs a dynamic threshold algorithm to identify the artery walls and then utilizes a correlation based tracking technique to estimate arterial distension. The end-diastolic echo signals are averaged to reduce error in the automated diameter measurement process. The instrument allows automated measurement of the various measures of arterial compliance with minimal operator intervention. The performance of the virtual instrument was first analyzed using simulated data sets to establish the maximum measurement accuracy achievable under different input signal to noise ratio (SNR) levels. The system could measure distension with accuracy better than 10 μm for positive SNR. The measurement error in diameter was less than 1%. The system was then thoroughly evaluated by the experiments conducted on phantom models of the carotid artery and the accuracy and resolution were found to meet the requirements of the application. Measurements performed on human volunteers indicate that the instrument can measure arterial distension with a precision better than 5%. The end-diastolic arterial diameter can be measured with a precision better than 2% and an accuracy of 1%. The measurement system could lead to the development of small, portable, and inexpensive equipment for estimation of arterial compliance suitable in mass screening of "at risk" patients. The automated compliance measurement algorithm implemented in the instrument requires minimal operator input. The instrument could pave the way for dedicated systems for arterial compliance evaluation targeted at the general medical practitioner who has little or no expertise in vascular ultrasonography.read more
Citations
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Journal ArticleDOI
Bi-Modal Arterial Compliance Probe for Calibration-Free Cuffless Blood Pressure Estimation
TL;DR: The feasibility of calibration-free, cuffless BP measurement at an arterial site of interest was demonstrated with a level of acceptable accuracy and the potential utility of the proposed method and system in hypertension screening and local evaluation of arterial stiffness indices was demonstrated.
Journal ArticleDOI
Technical Validation of ARTSENS–An Image Free Device for Evaluation of Vascular Stiffness
Jayaraj Joseph,Ravikumar Radhakrishnan,Shitanshu Kusmakar,Arya Sree Thrivikraman,Mohanasankar Sivaprakasam +4 more
TL;DR: The feasibility of the novel ARTSENS device in performing accurate in vivo measurements of arterial stiffness is verified, a device for image free, noninvasive, automated evaluation of vascular stiffness amenable for field use.
Proceedings ArticleDOI
Automated system for imageless evaluation of arterial compliance
TL;DR: An imageless portable system for automated estimation of local arterial compliance, designed to be operated by a general medical practitioner with no prior knowledge of ultrasonography, and used for developing an inexpensive cardiovascular screening device for large scale deployment in primary health care centers.
Journal ArticleDOI
Automatic Measurement of End-Diastolic Arterial Lumen Diameter in ARTSENS
TL;DR: A novel approach using the autocorrelation of echoes from opposite walls of the artery has been discussed, to bring down the curve fitting time and facilitate processing on low-end processors.
Journal ArticleDOI
ARTSENS® Pen-portable easy-to-use device for carotid stiffness measurement: technology validation and clinical-utility assessment.
Jayaraj Joseph,Raj Kiran,P M Nabeel,Malay Ilesh Shah,Arun Bhaskar,Chandra Ganesh,Suresh Seshadri,Mohanasankar Sivaprakasam +7 more
TL;DR: The study results revealed the sensitivity of ARTSENS® Pen to detect changes in arterial stiffness with age, and the easy-to-use technology and the automated algorithms of the ARtsENS Pen make it suitable for cardiovascular risk assessment in resource-constrained settings.
References
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Proceedings ArticleDOI
A virtual instrument for real time in vivo measurement of carotid artery compliance
Jayaraj Joseph,V. Jayashankar +1 more
TL;DR: The instrument gives a display of the variation of carotid diameter in real time and calculates the various estimates of arterial compliance from the analyzed data.
Proceedings ArticleDOI
An improved echo tracking algorithm for arterial distensibility measurements
Jayaraj Joseph,V. Jayashankar +1 more
TL;DR: An automatic method that uses an adaptive threshold to track the desired number of echoes and measure the artery diameter accurately is proposed that could be used along with single element transducer based ultrasound measurement systems as well as B-mode scanners.
Proceedings ArticleDOI
Estimation of carotid diameter with heartbeat on longitudinal B-mode ultrasonic images
TL;DR: If the diameter of carotid artery can be accurately estimated, it is possible to imply for initial inference of the presence of arteriosclerosis and in future studies, it has to be assessed with comparisons to anaother established method.