Journal ArticleDOI
Abdominoperineal resection provides better local control but equivalent overall survival to local excision of anorectal malignant melanoma: a systematic review
Akihisa Matsuda,Masao Miyashita,Satoshi Matsumoto,Goro Takahashi,Takeshi Matsutani,Takeshi Yamada,Taro Kishi,Eiji Uchida +7 more
TLDR
It is suggested that APR has no survival benefit; however, APR confers better local control than LE, given that local failures after LE could be managed by salvage surgery, minimizing morbidity and maximizing quality of life should be the focus in surgical treatment of ARMM.Abstract:
Objective:To determine whether the extent of surgery is associated with survival in anorectal malignant melanoma (ARMM).Background:ARMM is a rare and highly malignant neoplasm with unfavorable prognosis. The optimal surgical management, abdominoperineal resection (APR) or local excision (LE), has beread more
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Chinese Guidelines on the Diagnosis and Treatment of Melanoma (2015 Edition)
Jun Guo,Shukui Qin,Jun Liang,Tongyu Lin,Lu Si,Xiaohong Chen,Zhihong Chi,Chuanliang Cui,Nan Du,Yun Fan,Kangsheng Gu,Fang Li,Junling Li,Yongheng Li,Houjie Liang,Jiwei Liu,Man Lu,Aiping Lu,Kejun Nan,Xiaohui Niu,Hongming Pan,Guoxin Ren,Xiubao Ren,Yongqian Shu,Xin Song,Min Tao,Baocheng Wang,Wenbin Wei,Di Wu,L Y Wu,Aiwen Wu,Xiaolin Xu,Junyi Zhang,Xiaoshi Zhang,Yiping Zhang,Huiyan Zhu +35 more
TL;DR: The 2015 edition of the Chinese Guidelines on the Diagnosis and Treatment of Melanoma was finalized after repeated and wide consultations with multidisciplinary experts and updated and added with much new information, with an attempt to provide the up-todated and reliable instructions on clinical practices based recent scientific evidences.
Journal ArticleDOI
Extensive surgery and lymphadenectomy do not improve survival in primary melanoma of the anorectum: results from analysis of a large database (SEER)
TL;DR: Analysis of data obtained from a national representative database finds the prognostic value of positive loco‐regional lymph nodes and the impact of lymphadenectomy on overall survival are unclear.
Journal ArticleDOI
Clinical Characteristics of Malignant Melanoma in Southwest China: A Single-Center Series of 82 Consecutive Cases and a Meta-Analysis of 958 Reported Cases.
TL;DR: The clinical characteristics of melanoma in Chinese were different from those in Caucasians, and ulcer, tumor margins, and lymph node metastasis were significantly associated with prognosis.
Journal ArticleDOI
Chinese Guidelines on the Diagnosis and Treatment of Melanoma (2015 Edition).
Jun Guo,Shukui Qin,Jun Liang,Tongyu Lin,Lu Si,Xiaohong Chen,Zhihong Chi,Chuanliang Cui,Nan Du,Yun Fan,Kangsheng Gu,Fang Li,Junling Li,Yongheng Li,Houjie Liang,Jiwei Liu,Man Lu,Aiping Lu,Kejun Nan,Xiaohui Niu,Hongming Pan,Guoxin Ren,Xiubao Ren,Yongqian Shu,Xin Song,Min Tao,Baocheng Wang,Wenbin Wei,Di Wu,L Y Wu,Aiwen Wu,Xiaolin Xu,Junyi Zhang,Xiaoshi Zhang,Yiping Zhang,Huiyan Zhu +35 more
TL;DR: The 2015 edition of the Chinese Guidelines on the Diagnosis and Treatment of Melanoma was finalized after repeated and wide consultations with multidisciplinary experts and updated and added with much new information, with an attempt to provide the up-to-dated and reliable instructions on clinical practices based recent scientific evidences.
Journal ArticleDOI
Abdominal perineal resection or wilde local excision in primary anorectal malignant melanoma. Case report and review.
Saverio Latteri,Michele Teodoro,Michele Malaguarnera,Maurizio Mannino,Giuseppe Currò,Gaetano La Greca +5 more
TL;DR: The higher serum levels of LDH and YKL-40 are suggestive for Anorectal Melanoma diagnosis and the decrease of these findings may be associated with good prognosis.
References
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Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
TL;DR: The QUOROM Statement (QUality Of Reporting Of Meta-analyses) as mentioned in this paper was developed to address the suboptimal reporting of systematic reviews and meta-analysis of randomized controlled trials.
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Bias in meta-analysis detected by a simple, graphical test
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Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
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Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
David Moher,A. Liberati,Jennifer Tetzlaff,Douglas G. Altman,Gerd Antes,David C. Atkins,Virginia Barbour,Nick Barrowman,Jesse A. Berlin,Jocalyn Clark,Mike Clarke,Deborah J. Cook,Roberto D'Amico,Jonathan J Deeks,Philip J. Devereaux,Kay Dickersin,Matthias Egger,E Ernst,Peter C. Gøtzsche,Jeremy M. Grimshaw,G. H. Guyatt,Julian P T Higgins,Ioannidis Jpa.,Jos Kleijnen,Tom Lang,Nicola Magrini,D McNamee,Lorenzo Moja,Cynthia D. Mulrow,Maryann Napoli,Andrew D Oxman,B Pham,Drummond Rennie,Margaret Sampson,Kenneth F. Schulz,Paul G. Shekelle,David Tovey,Peter Tugwell +37 more
TL;DR: The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) as discussed by the authors is an update of the QUOROM guidelines for reporting systematic reviews and meta-analyses.
Journal ArticleDOI
Ipilimumab plus Dacarbazine for Previously Untreated Metastatic Melanoma
Caroline Robert,Luc Thomas,Igor Bondarenko,Steven J. O'Day,Jeffrey S. Weber,Claus Garbe,Céleste Lebbé,Jean Francois Baurain,Alessandro Testori,Jean-Jacques Grob,Neville Davidson,Jon M. Richards,Michele Maio,Axel Hauschild,Wilson H. Miller,Pere Gascón,Michal Lotem,Kaan Harmankaya,Ramy Ibrahim,Stephen Francis,Tai-Tsang Chen,R. Humphrey,Axel Hoos,Jedd D. Wolchok +23 more
TL;DR: Ipilimumab (at a dose of 10 mg per kilogram) in combination with dacarbazine, as compared with dACarbazine plus placebo, improved overall survival in patients with previously untreated metastatic melanoma.