Open AccessJournal Article
Accumulation of biologically active furanocoumarins in Ruta graveolens ssp. divaricata (Tenore) Gams in vitro culture.
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TLDR
Investigation of dynamics of accumulation of five linear furanocoumarins and umbelliferone in stationary liquid cultures of Ruta graveolens ssp.Abstract:
The study was designed to investigate dynamics of accumulation of five linear furanocoumarins and umbelliferone in stationary liquid cultures of Ruta graveolens ssp. divaricata (Tenore) Gams during 6-week growth cycles. The contents of individual metabolites in biomass increased 1.8-3.5 times while their total content rose 2.3 times. Maximum contents of xanthotoxin, bergapten and isopimpinellin (112.3, 76.2 and 84.0mg/100g d.w., respectively) and maximum total content of all metabolites (283.4 mg/100 g d.w.), obtained on 35th culture day, are interesting from practical point of view.read more
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Journal ArticleDOI
Production of bioactive phenolic acids and furanocoumarins in in vitro cultures of Ruta graveolens L. and Ruta graveolens ssp . divaricata (Tenore) Gams. under different light conditions
TL;DR: Both white light and blue light were equally beneficial for the total production of phenolic acids in cultures of both plants, whereas thetotal production of furanocoumarins was clearly better stimulated by blue light in R. graveolens and by darkness in the subspecies.
Journal ArticleDOI
Accumulation of dibenzocyclooctadiene lignans in agar cultures and in stationary and agitated liquid cultures of Schisandra chinensis (Turcz.) Baill.
Agnieszka Szopa,Adam Kokotkiewicz,Urszula Marzec-Wróblewska,Adam Buciński,Maria Luczkiewicz,Halina Ekiert +5 more
TL;DR: This report documents the potential usefulness of S. chinensis shoot cultures cultivated in liquid systems for practical purposes and quantification of fourteen dibenzocyclooctadiene lignans identified based on co-chromatography with authentic standards using high-performance liquid chromatography with diode array detection and electrospray ionization mass spectrometry methods.
Journal ArticleDOI
Genetic transformation of Ruta graveolens L. by Agrobacterium rhizogenes: hairy root cultures a promising approach for production of coumarins and furanocoumarins
Matylda Sidwa-Gorycka,Aleksandra Królicka,Aleksandra Orlita,Edmund Maliński,Marek Gołębiowski,Jolanta Kumirska,Agnieszka Chromik,Edyta Biskup,Piotr Stepnowski,Ewa Lojkowska +9 more
TL;DR: The levels of nearly all coumarins and alkaloids in hairy roots cultured in the darkness were higher than those accumulated under a photoperiod mode.
Journal Article
Bioprospecting for drug research and functional foods for the prevention of diseases—Role of flavonoids in drug development
TL;DR: Research in the area of chemistry of natural products when coupled with sources of local traditional medicines and aided by pharmacological and antimicrobial studies may lead to the development of newer and effective drugs.
Journal ArticleDOI
Production of deoxyschizandrin and γ-schizandrin in shoot-differentiating and undifferentiating callus cultures of Schisandra chinensis (Turcz.) Baill. (Chinese magnolia vine).
Agnieszka Szopa,Halina Ekiert +1 more
TL;DR: The obtained high amounts of deoxyschizandrin in the extracts of shoot-differentiating callus are of interest from the practical perspective and the levels of both compounds were dependent on the concentration of BA and NAA in the MS medium variants.
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Accumulation of biologically active furanocoumarins in agitated cultures of Ruta graveolens L. and Ruta graveolens ssp. divaricata (Tenore) Gams.
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