Activation of lipoprotein lipase by lipoprotein fractions of human serum
Dennis M. Bier,Richard J. Havel +1 more
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TLDR
Observations suggest that one or more of the major apoproteins of very low density lipoins, present as a minor constituent of high density lipoprotein, may be required for the activation process of triglycerides in fat emulsions.About:
This article is published in Journal of Lipid Research.The article was published on 1970-11-01 and is currently open access. It has received 104 citations till now. The article focuses on the topics: Intermediate-density lipoprotein & Lipoprotein lipase.read more
Citations
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Hypertriglyceridemia associated with deficiency of apolipoprotein C-II.
TL;DR: A 59-year-old man with severe hypertriglyceridemia and no post-heparin lipolytic activity was studied and it is concluded that this patient's hyperlipoproteinemia resulted from a deficiency of apolipoprotein C-II.
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Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man.
TL;DR: The results obtained demonstrate that high density lipoproteins contribute certain functionally important polar constituents to chylomicrons during alimentary lipemia in man and suggest that they also receive surface constituents from chylomaticrons during the course of their metabolism.
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Inhibition of lipoprotein lipase by an apoprotein of human very low density lipoprotein.
W. Virgil Brown,M.L. Baginsky +1 more
TL;DR: ApoLp-Ala consistently inhibits LPL when present at levels above 2% of the substrate (w/w), and this inhibition was not overcome by addition of phospholipid, apoLP-Glu, or more enzyme.
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A proposal linking atherogenesis to the interaction of endothelial lipoprotein lipase with triglyceride-rich lipoproteins.
TL;DR: The finding that cholesterol can enter the normal aortic wall as a constituent of lipoprotein, primarily beta-lipop Protein, suggests the possibility of a causal relationship between hypercholesterolemia and cholesterol in the arterial wall.
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Role of Specific Glycopeptides of Human Serum Lipoproteins in the Activation of Lipoprotein Lipase
TL;DR: It is suggested that specific glycopeptides are required for the action of lipoprotein lipase on emulsified triglycerides and suggest that they are important components of the mechanism for extra-hepatic utilization of plasma triglycerides.
References
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The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum
TL;DR: The relatively low density of the lipoproteins was utilized by Lindgren, Elliott, and Gofman to separate them from the other serum proteins by ultracentrifugal flotation, and quantitation was subsequently performed by refractometric methods in the analytical ultracentRifuge.
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A relation between non-esterified fatty acids in plasma and the metabolism of glucose
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Studies of the Proteins in Human Plasma Very Low Density Lipoproteins
TL;DR: The protein components of human plasma very low density lipoproteins were studied following partial and total delipidation and their purity was established by immunochemical analysis and polyacrylamide gel electrophoresis.