Activation of plasma by contact with glass: evidence for a common reaction which releases plasma kinin and initiates coagulation.
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This article is published in The Journal of Physiology.The article was published on 1958-11-10 and is currently open access. It has received 249 citations till now. The article focuses on the topics: Coagulation (water treatment).read more
Citations
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Antihemostatic, antiinflammatory, and immunosuppressive properties of the saliva of a tick, Ixodes dammini.
TL;DR: Pilocarpine-induced saliva of the tick, Ixodes dammini, inhibited platelet aggregation triggered by ADP and collagen, as well as platelet- aggregation factor, and apyrase activity and an anticoagulant were found.
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Williams trait. Human kininogen deficiency with diminished levels of plasminogen proactivator and prekallikrein associated with abnormalities of the Hageman factor-dependent pathways.
Robert W. Colman,Andranik Bagdasarian,Richard C. Talamo,C F Scott,M Seavey,J A Guimaraes,J V Pierce,A P Kaplan +7 more
TL;DR: Kininogen is a critical factor required for the functioning of Hageman factor-dependent coagulation and fibrinolysis and for the activation of prekallikrein.
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THE INHIBITION OF PLASMIN, PLASMA KALLIKREIN, PLASMA PERMEABILITY FACTOR, AND THE C'1r SUBCOMPONENT OF THE FIRST COMPONENT OF COMPLEMENT BY SERUM C'1 ESTERASE INHIBITOR
TL;DR: C'1 esterase inhibitor has been found to block the actions of plasmin and the C'1r subcomponent of the first component of complement, and to retard the generation of PF/Dil.
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Role of surface in surface-dependent activation of Hageman factor (blood coagulation factor XII).
TL;DR: The results suggest that substances classically known as "activating surfaces" promote the activation of Hageman factor indirectly by altering its structure such that it is much more susceptible to proteolytic activation by other plasma or cellular proteases.
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The inflammatory response
W. G. Spector,D. A. Willoughby +1 more
TL;DR: The role of polypeptides, permeability-Increasing Globulins, and Inhibitors in inflaming, and the role of POLYPEPTIDES, PLASMA KININS, KININ-FORMing ENZYMES, and GLOBULin PF in InFLAM-
References
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Bradykinin, a hypotensive and smooth muscle stimulating factor released from plasma globulin by snake venoms and by trypsin.
TL;DR: The stimulating principle disappeared from the blood very quickly after injection and could not be detected in samples taken a few minutes later, and no desensitization could be observed after several additions of the serum to the perfusing bath containing the piece of guinea pig ileum.
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A familial hemorrhagic trait associated with a deficiency of a clot-promoting fraction of plasma.
Oscar D. Ratnoff,Joan E. Colopy +1 more
Journal ArticleDOI
Pain-producing substance in human inflammatory exudates and plasma.
TL;DR: It is shown here that plasma does in fact develop labile pain-producing activity when collected and kept in a glass syringe, and that the active agent is probably a polypeptide resembling bradykinin in its actions.
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The kaolin clotting time a rapid one-stage method for diagnosis of coagulation defects
TL;DR: An additional difficulty whendealing with plasma is that, as thenumber of platelets decreases withincreasing centrifugation, the clotting time becomes more andmoresensitive to variations intheplatelet count and the results becomemore unpredictable.
Journal ArticleDOI
Initiation of blood coagulation by glass and related surfaces.
TL;DR: Recent evidence favours the view that the initial contact reaction takes place in the plasma, and indicates that surface is a quantitative factor in prothrombin utilization.
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A familial hemorrhagic trait associated with a deficiency of a clot-promoting fraction of plasma.
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Pain-producing substance in human inflammatory exudates and plasma.
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A prealbumin activator of prekallikrein : ii. derivation of activators of prekallikrein from active hageman factor by digestion with plasmin
Allen P. Kaplan,K. Frank Austen +1 more