Acute encephalitis in India: An unfolding tragedy.
TLDR
While existing environmental, climatic and socio-economic factors contribute to the risk, the impact can be worse with weak health systems, inadequate resources and poor preparedness and response mechanisms.Abstract:
In spite of a major economic and epidemiological transitions being underway, infectious diseases continue to remain a major public health problem in India1,2. In addition to a number of endemic diseases, recent epidemics of H1N1pdm09, dengue and other infectious diseases demonstrate the ongoing vulnerability to the threat of emerging infections3. While existing environmental, climatic and socio-economic factors contribute to the risk, the impact can be worse with weak health systems, inadequate resources and poor preparedness and response mechanisms.read more
Citations
More filters
Journal ArticleDOI
Scrub typhus strikes back: Are we ready?
Rina Tilak,Renuka Kunte +1 more
TL;DR: Over the last decade, there has been a global increase in the number of outbreaks of Scrub typhus, be it the military occupied areas or the civil population at large, and areas seeking concerted deliberations and actions so that the challenges posed by scrub typhus can be addressed.
Journal ArticleDOI
Morvan's syndrome-is a pathogen behind the curtain?
Rohit Singh,Pritam Das,Upinder Kaur,Anamika Misra,Ashis Kumar Choudhury,Sukdev Manna,Rohit Gaude,Deepak Kumar Gautam,Indrajeet Singh Gambhir,Sankha Shubhra Chakrabarti +9 more
TL;DR: It is hypothesized that Morvan’s syndrome and other less characterized autoimmune encephalitis/peripheral nervous system syndromes may have infectious triggers and a possible viral trigger may result in generation of autoantibodies which result in the typical manifestations.
Journal ArticleDOI
A Novel IoT-Fog-Cloud-based Healthcare System for Monitoring and Preventing Encephalitis
Munish Bhatia,Sapna Kumari +1 more
TL;DR: This work presents a Tri-logical IoT-fog-cloud (TIFC) model to collect AES data for monitoring, and controlling the outbreak over the Spatio-temporal manner, and concludes that the proposed system has outperformed other decision models in terms of statistical parameters including accuracy, f-measure, and reliability.
Journal ArticleDOI
An algorithmic approach to identifying the aetiology of acute encephalitis syndrome in India: results of a 4-year enhanced surveillance study.
Vasanthapuram Ravi,Shafeeq K. Shahul Hameed,Anita Desai,Reeta S. Mani,Ch. Vijay Bhasker Reddy,Anoop Velayudhan,Ravi Prakash Yadav,A Jain,Lahari Saikia,Achinta K Borthakur,Ajanta Sharma,Daiji Gogoi Mohan,Bhaswati Bhandopadhyay,Nemai Bhattacharya,L Inamdar,Shah Hossain,Sharon Daves,James J. Sejvar,A C Dhariwal,P. Sen,S. Ajay Venkatesh,Jagdish Prasad,Kayla F. Laserson,Padmini Srikantiah +23 more
TL;DR: A large-scale, systematic surveillance study in India, patients presenting with acute encephalitis syndrome (i.e., acute onset of fever with altered mental status, seizure, or both) to any of the 18 participating hospitals across Uttar Pradesh, West Bengal, and Assam were evaluated for JEV (serum and cerebrospinal fluid [CSF] IgM ELISA) per standard of care as discussed by the authors .
Journal ArticleDOI
A Novel Multiplex RT-PCR Assay for Simultaneous Detection of Dengue and Chikungunya Viruses
Md. Ariful Islam,Mohamed E. El Zowalaty,Mohamed E. El Zowalaty,Sumaiya Islam,Mohiuddin Sharif,Rajibur Rahman,Mohammad Amin,Mortuza Ali,Tanvir Rahman,Kouichi Morita,Hossam M. Ashour,Hossam M. Ashour +11 more
TL;DR: The sensitivity for serotype detection of DENV and CHIKV was superior to the virus isolation method and the antigen detection method using the Dengue NS1-Ag assay and this novel mRT-PCR method can be used for molecular epidemiological surveillance ofDENV and Chikungunya virus in epidemic and endemic countries.
References
More filters
Journal ArticleDOI
Enteroviruses in patients with acute encephalitis, uttar pradesh, India.
Gajanan N. Sapkal,Vijay P. Bondre,Pradip V. Fulmali,Pooja R. Patil,Varanasi Gopalkrishna,Vipul Dadhania,Vijay M. Ayachit,Daya Gangale,K P Kushwaha,A K Rathi,Shobha D. Chitambar,Akhilesh C. Mishra,Milind M. Gore +12 more
TL;DR: An outbreak of viral encephalitis occurred in northern India in 2006 and attempts to identify an etiologic agent in cerebrospinal fluid by using reverse transcription–PCR showed positivity to enterovirus (EV) in 66 patients.
Journal Article
Emerging & re-emerging infections in India: An overview
TL;DR: A comprehensive national strategy on infectious diseases cutting across all relevant sectors with emphasis on strengthened surveillance, rapid response, partnership building and research to guide public policy is needed in India.
Journal ArticleDOI
Association of acute toxic encephalopathy with litchi consumption in an outbreak in Muzaffarpur, India, 2014: a case-control study
Aakash Shrivastava,Anil Kumar,Jerry D. Thomas,Kayla F. Laserson,Gyan Bhushan,Melissa D. Carter,Mala Chhabra,Veena Mittal,Shashi Khare,James J. Sejvar,Mayank Dwivedi,Samantha L. Isenberg,Rudolph C. Johnson,James L. Pirkle,Jon D. Sharer,Patricia L. Hall,Rajesh K. Yadav,Rajesh K. Yadav,Anoop Velayudhan,Anoop Velayudhan,Mohan Kumar Papanna,Mohan Kumar Papanna,Pankaj Singh,D Somashekar,Arghya Pradhan,Kapil Goel,Rajesh Pandey,Mohan Kumar,Satish Kumar,Amit Chakrabarti,P. Sivaperumal,A. Ramesh Kumar,Joshua G. Schier,Arthur Chang,Leigh Ann Graham,Thomas P. Mathews,Darryl Johnson,Liza Valentin,Kathleen L. Caldwell,Jeffery M. Jarrett,Leslie A. Harden,Gary R. Takeoka,Suxiang Tong,Krista Queen,Clinton R. Paden,Anne M. Whitney,Dana L. Haberling,Ram Singh,Ravi Shankar Singh,Kenneth C Earhart,A C Dhariwal,L S Chauhan,S. Venkatesh,Padmini Srikantiah +53 more
TL;DR: The investigation suggests an outbreak of acute encephalopathy in Muzaffarpur associated with both hypoglycin A and MCPG toxicity, which is recommended to prevent illness and reduce mortality in the region.
Journal ArticleDOI
A review of Japanese encephalitis in Uttar Pradesh, India.
Roop Kumari,Pyare L Joshi +1 more
TL;DR: JE is closely associated with the pattern of precipitation, flooding and rice production systems and continuous monitoring of vector populations and JE virus infection rates in vector mosquitoes will help in predicting an outbreak and in taking effective intervention measures.
Journal ArticleDOI
Public Health Challenges in India: Seizing the Opportunities.
TL;DR: While financial inclusion and social security measures are being implemented by the Government to bridge economic inequalities, health sector too must ensure that health disparities between and among social and economic classes are also addressed adequately.