Journal ArticleDOI
Adrenal involvement in conditioned immunosuppression.
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TLDR
Conditioned animals provided with saccharin at the time of antigen injection showed an attenuated antibody response, confirming the results of previous studies and providing no support for the hypothesis of an adrenocortical mediation of conditioned immunosuppressive effects.About:
This article is published in International Journal of Immunopharmacology.The article was published on 1979-01-01. It has received 90 citations till now. The article focuses on the topics: Taste aversion & Saccharin.read more
Citations
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Noradrenergic sympathetic neural interactions with the immune system: structure and function.
David L. Felten,Suzanne Y. Felten,Denise L. Bellinger,Sonia L. Carlson,Kurt D. Ackerman,Kelley S. Madden,John A. Olschowki,Shmuel Livnat +7 more
TL;DR: It is proposed that NE in lymphoid organs fulfills the criteria for neurotransmission, estabUshed in more traditional efTector tissues such as the heart, and plays a role in the modulation of immune responses.
Journal ArticleDOI
Behaviorally conditioned immunosuppression and murine systemic lupus erythematosus
Robert Ader,Nicholas Cohen +1 more
TL;DR: Development of autoimmune disease in female New Zealand hybrid mice was dramatically modified by classical conditioning of immunosuppression and the rate of development of proteinuria and mortality were significantly retarded.
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Stress-induced suppression of immunity in adrenalectomized rats.
TL;DR: The results demonstrate that corticosteroid independent mechanisms participate in the suppression of lymphocyte function by stressors, indicating that the modulation of immunity by stress is complex and multidetermined.
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Suppression of immunity by stress: Effect of a graded series of stressors on lymphocyte stimulation in the rat.
TL;DR: In rats a graded series of stressors produced progressively greater suppression of lymphocyte function, as measured by the number of circulating lymphocytes and by phytohemagglutinin stimulation, which suggests that stress suppresses immunity in proportion to the intensity of the stressor.
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Interactions between the brain and the immune system
TL;DR: The immunologic effects of learning, an essential feedforward mechanism, suggest that, like direct neural and endocrine processes, behavior can, under appropriate circumstances, serve an immunoregulatory function in vivo.
References
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Journal ArticleDOI
Behavioral Regulation of the Milieu Interne in Man and Rat
TL;DR: This specialized conditioning mechanism, which specifically adjusts gustatory hedonic values through delayed visceral feedback, is widespread among animals, including man and rat, and is based on the animals' having similar gustatory systems, similar convergence of gustatory and internal afferents to the nucleus solitarius, and similar midbrain regulatory mechanisms.
Journal ArticleDOI
Conditioned Aversion to Saccharin Resulting from Exposure to Gamma Radiation
Journal ArticleDOI
Behaviorally Conditioned Immunosuppression
Robert Ader,Nicholas Cohen +1 more
TL;DR: An illness-induced taste aversion was conditioned in rats by pairing saccharin with cyclophosphamide, an immunosuppressive agent, and there was no attenuation of hemagglutinating antibody titers in response to injection with antigen.
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Augmentation of delayed-type hypersensitivity by doses of cyclophosphamide which do not affect antibody responses.
TL;DR: The results suggest that antibody feedback is not the sole regulator of delayed reactions; the possibility that suppressor T cells may also be involved is discussed.
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Illness-Induced Aversions in Rat and Quail: Relative Salience of Visual and Gustatory Cues
TL;DR: Bobwhite quail, like the rat, learn in one trial to avoid flavored water when illness is induced by a drug � 12 hour after drinking.
Related Papers (5)
Behaviorally conditioned immunosuppression and murine systemic lupus erythematosus
Robert Ader,Nicholas Cohen +1 more