P
Philip W. Askenase
Researcher at Yale University
Publications - 217
Citations - 13180
Philip W. Askenase is an academic researcher from Yale University. The author has contributed to research in topics: T cell & Antigen. The author has an hindex of 57, co-authored 214 publications receiving 12438 citations. Previous affiliations of Philip W. Askenase include Stony Brook University & Tufts University.
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Journal ArticleDOI
Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation
Hina Kalra,Richard J. Simpson,Hong Ji,Elena Aikawa,Peter Altevogt,Philip W. Askenase,Vincent C. Bond,Francesc E. Borràs,Xandra O. Breakefield,Vivian Budnik,Edit I. Buzás,Giovanni Camussi,Aled Clayton,Emanuele Cocucci,Juan M. Falcón-Pérez,Susanne Gabrielsson,Yong Song Gho,Dwijendra K. Gupta,H. C. Harsha,An Hendrix,Andrew F. Hill,Jameel M. Inal,Guido Jenster,Eva-Maria Krämer-Albers,Sai Kiang Lim,Alicia Llorente,Jan Lötvall,Antonio Marcilla,Lucia Mincheva-Nilsson,Irina Nazarenko,Rienk Nieuwland,Esther N. M. Nolte-‘t Hoen,Akhilesh Pandey,Tushar Patel,Melissa G. Piper,Stefano Pluchino,T. S. Keshava Prasad,Lawrence Rajendran,Graça Raposo,Michel Record,Gavin E. Reid,Francisco Sánchez-Madrid,Raymond M. Schiffelers,Pia Siljander,Allan Stensballe,Willem Stoorvogel,Douglas D. Taylor,Clotilde Théry,Hadi Valadi,Bas W.M. van Balkom,Jesús Vázquez,Michel Vidal,Marca H. M. Wauben,María Yáñez-Mó,Margot Zoeller,Suresh Mathivanan +55 more
TL;DR: Vesiclepedia is a community-annotated compendium of molecular data on extracellular vesicles that aims to provide a single authoritative source for information on vesicle structure and function.
Journal ArticleDOI
Critical role for NALP3/CIAS1/cryopyrin in innate and adaptive immunity through its regulation of caspase-1
Fayyaz S. Sutterwala,Yasunori Ogura,Marian Szczepanik,Marian Szczepanik,Maria Lara-Tejero,G. Scott Lichtenberger,Ethan P. Grant,John Bertin,Anthony J. Coyle,Jorge E. Galán,Philip W. Askenase,Richard A. Flavell +11 more
TL;DR: It is shown that ASC- and NALP3-deficient mice also demonstrate an impaired contact hypersensitivity response to the hapten trinitrophenylchloride, suggesting that NALp3 plays a specific role in the caspase-1 activation pathway.
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Development of atopic dermatitis-like skin lesion with IgE hyperproduction in NC/Nga mice.
Hiroshi Matsuda,Naohiro Watanabe,Gregory P. Geba,J Sperl,Masaoki Tsudzuki,Jun Hiroi,M Matsumoto,Hiroko Ushio,S Saito,Philip W. Askenase,Chisei Ra +10 more
TL;DR: It was found that skin lesions, which were clinically and histologically very similar to human AD, spontaneously appeared on the face, neck, ears and dorsal skin of inbred NC/Nga mice when they were raised in non-sterile (conventional) circumstances, but not under specific pathogen-free conditions.
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Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses
Silke Paust,Silke Paust,Harvinder S. Gill,Harvinder S. Gill,Bao-Zhong Wang,Michael P Flynn,E. Ashley Moseman,Balimkiz Senman,Marian Szczepanik,Marian Szczepanik,Amalio Telenti,Amalio Telenti,Philip W. Askenase,Richard W. Compans,Ulrich H. von Andrian +14 more
TL;DR: Hepatic NK cells can develop adaptive immunity to structurally diverse antigens, an activity that requires NK cell–expressed CXCR6, a chemokine receptor on NK cells that was required for the persistence of memory NK cells but not for antigen recognition.
Journal ArticleDOI
Augmentation of delayed-type hypersensitivity by doses of cyclophosphamide which do not affect antibody responses.
TL;DR: The results suggest that antibody feedback is not the sole regulator of delayed reactions; the possibility that suppressor T cells may also be involved is discussed.