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Journal ArticleDOI

Aggregatibacter actinomycetemcomitans biofilm can be inactivated by methylene blue-mediated photodynamic therapy

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TLDR
The results of this study suggest that A. actinomycetemcomitans biofilm can be inactivated by MB mediated APDI.
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This article is published in Photodiagnosis and Photodynamic Therapy.The article was published on 2015-03-01. It has received 38 citations till now.

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Journal ArticleDOI

Antimicrobial Photodynamic Therapy to Control Clinically Relevant Biofilm Infections.

TL;DR: Antimicrobial Photodynamic therapy (aPDT) had been recently proposed to combat clinically relevant biofilms such as dental biofilmms, ventilator associated pneumonia, chronic wound infections, oral candidiasis, and chronic rhinosinusitis and a brief section provides suggestions for future research.
Journal ArticleDOI

The application of antimicrobial photodynamic therapy (aPDT) in dentistry: a critical review

TL;DR: The goal of this review was to summarize the results of research on aPDT in dentistry using the PubMed database focusing on recent studies of the effectiveness aPDt in decreasing microorganisms and microbial biofilms, and also to describe a PDT effects, mechanisms of action and applications.
Journal ArticleDOI

Antimicrobial efficacy of methylene blue-mediated photodynamic therapy on titanium alloy surfaces in vitro.

TL;DR: MB-mediated PDT could effectively kill the majority of bacteria on the titanium alloy surfaces of biofilm-contaminated implants compared with the MB alone, and exhibited better antibacterial efficacy with increase in the MB concentration and irradiation time.
Journal ArticleDOI

Antimicrobial photodynamic therapy—A discovery originating from the pre-antibiotic era in a novel periodontal therapy

TL;DR: It indicates, that aPDT has an influence on the extent of inflammation and further studies are needed to establish an optimal protocol of treatment combining mechanical debridement with photochemotherapy in order to obtain good treatment outcomes in patients.
Journal ArticleDOI

Photoinactivation Using Visible Light Plus Water-Filtered Infrared-A (vis+wIRA) and Chlorine e6 (Ce6) Eradicates Planktonic Periodontal Pathogens and Subgingival Biofilms

TL;DR: The significant antimicrobial effects revealed in this study highlight the potential of aPDT using this light source in combination with Ce6 as an adjunctive method to treat periodontitis as well as periimplantitis.
References
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Journal ArticleDOI

Photodynamic antimicrobial chemotherapy (PACT).

TL;DR: Photodynamic antimicrobial chemotherapy (PACT), which predates the related cancer regimen, is proposed as a potential, low-cost approach to the treatment of locally occurring infection.
Journal ArticleDOI

Photodynamic Therapy Targeted to Pathogens

TL;DR: This work has used genetically modified bioluminescent bacteria to follow the effect of PDT in infected wounds, burns, and soft tissue infections in mice and found that mice were saved from death due to sepsis and wound healing was improved.
Journal ArticleDOI

Bactericidal effects of different laser wavelengths on periodontopathic germs in photodynamic therapy.

TL;DR: Using a diode laser of proper power and wavelength to deliver 60 s of irradiation could be a useful adjunct with mechanical debridement in the prevention of the re-colonisation of subgingival lesions by pathogenic microorganisms.
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