Journal ArticleDOI
An Extremely Powerful Acylation Reaction of Alcohols with Acid Anhydrides Catalyzed by Trimethylsilyl Trifluoromethanesulfonate
TLDR
Trimethylsilyl trifluoromethanesulfonate is an excellent catalyst for the acylation of alcohols with acid anhydrides and was used in this paper.Abstract:
Trimethylsilyl trifluoromethanesulfonate is an excellent catalyst for the acylation of alcohols with acid anhydrides. Highly functionalized primary, secondary, tertiary, and allylic alcohols, and phenols, were acylated cleanly and efficiently and in a fraction of the time used under the standard DMAP conditions.read more
Citations
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N-Heterocyclic Carbenes as Versatile Nucleophilic Catalysts for Transesterification/Acylation Reactions
TL;DR: Imidazol-2-ylidenes, a family of N-heterocyclic carbenes (NHC), are efficient catalysts in the transesterification between esters and alcohols and form efficiently the corresponding esters in very short reaction times.
Journal ArticleDOI
Perchloric acid adsorbed on silica gel as a new, highly efficient, and versatile catalyst for acetylation of phenols, thiols, alcohols, and amines
TL;DR: Perchloric acid adsorbed on silica gel efficiently catalyses acetylation of structurally diverse phenols, alcohols, thiols, and amines under solvent free conditions.
Journal ArticleDOI
Bismuth(III) Triflate in Organic Synthesis
TL;DR: In this paper, the authors present a microreview of the uses of bismuth(III) triflate in organic synthesis, which is a new, cheap and environmentally friendly Lewis acid.
Journal ArticleDOI
Efficient Transesterification/Acylation Reactions Mediated by N-Heterocyclic Carbene Catalysts
TL;DR: The NHC-catalyzed transesterification protocol was simplified by generating the imidazol-2-ylidene catalysts in situ, and methyl and ethyl esters can be employed as protective agents for secondary alcohols in the presence of the more active alkyl-substituted NHC catalysts.
Journal ArticleDOI
Rapid, clean, and mild O-acetylation of alcohols and carbohydrates in an ionic liquid.
TL;DR: Archetypal O-acetylation reactions of alcohols and carbohydrates proceed rapidly in high yield under mild conditions in a dicyanamide based ionic liquid, that is not only an effective solvent but also an active base catalyst.
References
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Journal ArticleDOI
4-Dialkylaminopyridines as Highly Active Acylation Catalysts. [New synthetic method (25)]
TL;DR: The synthesis of 4-dialkylaminopyridines can be accomplished in two steps starting from pyridine as discussed by the authors, and these derivatives are approximately 104 times more active when used as acylation catalysts.
Journal ArticleDOI
N,N‐Dimethyl‐4‐pyridinamine, a Very Effective Acylation Catalyst
W. Steglich,G. Höfle +1 more
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Scandium Trifluoromethanesulfonate as an Extremely Active Lewis Acid Catalyst in Acylation of Alcohols with Acid Anhydrides and Mixed Anhydrides.
TL;DR: The method presented is especially effective for selective macrolactonization of omega-hydroxy carboxylic acids.
Journal ArticleDOI
Cobalt(II) chloride catalyzed acylation of alcohols with acetic anhydride: scope and mechanism
TL;DR: Cobalt(II) chloride catalyzes the acetylation of a variety of alcohols with acetic anhydride in excellent yield and can be selectively acylated in the presence of secondary and tertiary ones.