Journal ArticleDOI
Cobalt(II) chloride catalyzed acylation of alcohols with acetic anhydride: scope and mechanism
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TLDR
Cobalt(II) chloride catalyzes the acetylation of a variety of alcohols with acetic anhydride in excellent yield and can be selectively acylated in the presence of secondary and tertiary ones.Abstract:
Cobalt(II) chloride catalyzes the acetylation of a variety of alcohols with acetic anhydride in excellent yield. Primary hydroxyl groups can be selectively acylated in the presence of secondary and tertiary ones while the secondary hydroxyl groups can be preferentially acetylated in the presence of tertiary ones. Tertiary alcohols have been found to give ketones, acetoacetates, olefins, and diketene in addition to the acetateread more
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Journal ArticleDOI
Scandium Trifluoromethanesulfonate as an Extremely Active Lewis Acid Catalyst in Acylation of Alcohols with Acid Anhydrides and Mixed Anhydrides.
TL;DR: The method presented is especially effective for selective macrolactonization of omega-hydroxy carboxylic acids.
Journal ArticleDOI
N-Heterocyclic Carbenes as Versatile Nucleophilic Catalysts for Transesterification/Acylation Reactions
TL;DR: Imidazol-2-ylidenes, a family of N-heterocyclic carbenes (NHC), are efficient catalysts in the transesterification between esters and alcohols and form efficiently the corresponding esters in very short reaction times.
Journal ArticleDOI
An Extremely Powerful Acylation Reaction of Alcohols with Acid Anhydrides Catalyzed by Trimethylsilyl Trifluoromethanesulfonate
TL;DR: Trimethylsilyl trifluoromethanesulfonate is an excellent catalyst for the acylation of alcohols with acid anhydrides and was used in this paper.
Journal ArticleDOI
Efficient Transesterification/Acylation Reactions Mediated by N-Heterocyclic Carbene Catalysts
TL;DR: The NHC-catalyzed transesterification protocol was simplified by generating the imidazol-2-ylidene catalysts in situ, and methyl and ethyl esters can be employed as protective agents for secondary alcohols in the presence of the more active alkyl-substituted NHC catalysts.
Journal ArticleDOI
An efficient method for acylation reactions
P. Saravanan,Vinod K. Singh +1 more
TL;DR: In this article, a catalytic cycle has been proposed for the acylation reaction of alcohols, phenols, amines and thiols with acetic anhydride in CH 2 Cl 2 or acetic acid.