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An Investigation of Uncertainty and Sensitivity Analysis Techniques for Computer Models

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TLDR
This study investigates the applicability of three widely used techniques to three computer models having large uncertainties and varying degrees of complexity in order to highlight some of the problem areas that must be addressed in actual applications.
Abstract
Many different techniques have been proposed for performing uncertainty and sensitivity analyses on computer models for complex processes. The objective of the present study is to investigate the applicability of three widely used techniques to three computer models having large uncertainties and varying degrees of complexity in order to highlight some of the problem areas that must be addressed in actual applications. The following approaches to uncertainty and sensitivity analysis are considered: (1) response surface methodology based on input determined from a fractional factorial design; (2) Latin hypercube sampling with and without regression analysis; and (3) differential analysis. These techniques are investigated with respect to (1) ease of implementation, (2) flexibility, (3) estimation of the cumulative distribution function of the output, and (4) adaptability to different methods of sensitivity analysis. With respect to these criteria, the technique using Latin hypercube sampling and regression analysis had the best overall performance. The models used in the investigation are well documented, thus making it possible for researchers to make comparisons of other techniques with the results in this study.

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Citations
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A Methodology For Performing Global Uncertainty And Sensitivity Analysis In Systems Biology

TL;DR: This work develops methods for applying existing analytical tools to perform analyses on a variety of mathematical and computer models and provides a complete methodology for performing these analyses, in both deterministic and stochastic settings, and proposes novel techniques to handle problems encountered during these types of analyses.
Journal ArticleDOI

Latin hypercube sampling and the propagation of uncertainty in analyses of complex systems

TL;DR: The following techniques for uncertainty and sensitivity analysis are briefly summarized: Monte Carlo analysis, differential analysis, response surface methodology, Fourier amplitude sensitivity test, Sobol' variance decomposition, and fast probability integration.
Journal ArticleDOI

Importance measures in global sensitivity analysis of nonlinear models

TL;DR: In this paper, a new method of global sensitivity analysis of nonlinear models is proposed based on a measure of importance to calculate the fractional contribution of the input parameters to the variance of the model prediction.
References
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Journal ArticleDOI

A comparison of three methods for selecting values of input variables in the analysis of output from a computer code

TL;DR: In this paper, two sampling plans are examined as alternatives to simple random sampling in Monte Carlo studies and they are shown to be improvements over simple sampling with respect to variance for a class of estimators which includes the sample mean and the empirical distribution function.
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A distribution-free approach to inducing rank correlation among input variables

TL;DR: In this article, a method for inducing a desired rank correlation matrix on a multivariate input random variable for use in a simulation study is introduced, which preserves the exact form of the marginal distributions on the input variables, and may be used with any type of sampling scheme for which correlation of input variables is a meaningful concept.
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Ridge Regression in Practice

TL;DR: In this paper, a review of the theory of ridge regression and its relation to generalized inverse regression is presented along with the results of a simulation experiment and three examples of the use of the ridge regression in practice.

Risk methodology for geologic disposal of radioactive waste: small sample sensitivity analysis techniques for computer models, with an application to risk assessment

TL;DR: A generalization of Latin hypercube sampling is given that allows these areas of decision making in the face of uncertainty to be investigated without making additional computer runs.
Journal ArticleDOI

Small sample sensitivity analysis techniques for computer models.with an application to risk assessment

TL;DR: In this paper, Latin hypercube sampling has been shown to work well on this type of problem, and a judicious selection procedure for the choic of values of input variables is required, a variety of situations require that decisions and judgments be made in the face of uncertainty.
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