Angiomatoid fibrous histiocytoma: unusual sites and unusual morphology
Gang Chen,Andrew L. Folpe,Thomas V. Colby,Kesavan Sittampalam,Martine Patey,Ming Guang Chen,John K.C. Chan +6 more
TLDR
Comparison of the reported cases of extrasomatic angiomatoid fibrous histiocytoma with their somatic soft tissue counterparts showed a number of differences: higher mean age, slight male predominance (particularly for bone lesions), larger tumors, higher frequency of systemic symptoms, higher recurrence rate, myxoid change being more common and a muchHigher frequency of EWS/ATF1 gene fusion.About:
This article is published in Modern Pathology.The article was published on 2011-12-01 and is currently open access. It has received 125 citations till now. The article focuses on the topics: Angiomatoid fibrous histiocytoma & Soft Tissue Neoplasm.read more
Citations
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Journal ArticleDOI
Tumors With EWSR1-CREB1 and EWSR1-ATF1 Fusions: The Current Status
Khin Thway,Cyril Fisher +1 more
TL;DR: A review of the clinicopathologic and molecular features of this group of neoplasms unified by the presence of EWSR1-CREB1 and EWSR-ATF1 genetic fusions, which have now been consistently described in 5 histopathologically and behaviorally diverse neoplasm.
Journal ArticleDOI
The diversity of soft tissue tumours with EWSR1 gene rearrangements: a review
TL;DR: The diversity of the several soft tissue tumour types that are associated with rearrangement of the EWSR1 gene is reviewed.
Journal ArticleDOI
The Role of Molecular Testing in the Differential Diagnosis of Salivary Gland Carcinomas.
Alena Skálová,Göran Stenman,Roderick H.W. Simpson,Henrik Hellquist,David Slouka,Tomáš Svoboda,Justin A. Bishop,Jennifer L. Hunt,Ken-ichi Nibu,Alessandra Rinaldo,Vincent Vander Poorten,Vincent Vander Poorten,Kenneth O. Devaney,Petr Steiner,Alfio Ferlito +14 more
TL;DR: The clinicopathologic features of a selected group of salivary gland carcinomas with a focus on their distinctive genomic characteristics are described, finding them promising as prognostic biomarkers and targets of therapy.
Journal ArticleDOI
EWSR1 Fusions With CREB Family Transcription Factors Define a Novel Myxoid Mesenchymal Tumor With Predilection for Intracranial Location
Yu Chien Kao,Yun Shao Sung,Lei Zhang,Chun-Liang Chen,Sumathi Vaiyapuri,Marc K. Rosenblum,Cristina R. Antonescu +6 more
TL;DR: A distinct group of myxoid mesenchymal neoplasms occurring in children or young adults with a predilection for intracranial locations is reported, suggesting a novel entity.
Journal ArticleDOI
Angiomatoid fibrous histiocytoma: the current status of pathology and genetics.
Khin Thway,Cyril Fisher +1 more
TL;DR: The occurrence of AFH at several unusual anatomic sites and its spectrum of morphologic patterns can result in significant diagnostic difficulty, and correct diagnosis is particularly important because of its small risk of metastasis and death.
References
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Book ChapterDOI
Pathology and Genetics
TL;DR: Local aggressiveness consists in the invasion of contiguous structures and organs (spleen, stomach, left adrenal gland, colon, and peritoneum), whereas distant metastases can occur in liver, lungs, adrenals, kidneys, bones, brain, and skin.
Journal ArticleDOI
Angiomatoid malignant fibrous histiocytoma. A distinct fibrohistiocytic tumor of children and young adults simulating a vascular neoplasm
TL;DR: Most likely it is a tumor of fibroblast‐ and histiocyte‐like cells, akin to malignant fibrous histiocytoma, but different in its age incidence, microscopic appearance, and behavior.
Journal ArticleDOI
Benign schwannoma of the gastrointestinal tract: a clinicopathologic and immunohistochemical study.
TL;DR: A clinicopathologic and immunohistochemical review was made of 24 cases of distinctive nerve sheath tumors located in the gastrointestinal tract and it is proposed that these tumors be designated as benign schwannoma of theintestinal tract.
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Angiomatoid malignant fibrous histiocytoma. A distinct fibrohistiocytic tumor of children and young adults simulating a vascular neoplasm
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