Journal ArticleDOI
Antioxidant activity of dietary polyphenols as determined by a modified ferric reducing/antioxidant power assay
TLDR
The antioxidant (AO) activity of polyphenols (PPs) was determined for the first time using a modified FRAP (ferric reducing/antioxidant power) assay and polyphenol's AO efficiency seemed to depend on the extent of hydroxylation and conjugation.Abstract:
Most nonenzymatic antioxidant activity (scavenging of free radicals, inhibition of lipid peroxidation, etc.) is mediated by redox reactions. The antioxidant (AO) activity of polyphenols (PPs), as f...read more
Citations
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Journal ArticleDOI
The Chemistry behind Antioxidant Capacity Assays
TL;DR: This analysis suggests that the total phenols assay by FCR be used to quantify an antioxidant's reducing capacity and the ORAC assay to quantify peroxyl radical scavenging capacity, to comprehensively study different aspects of antioxidants.
Journal ArticleDOI
Standardized Methods for the Determination of Antioxidant Capacity and Phenolics in Foods and Dietary Supplements
TL;DR: Methods available for the measurement of antioxidant capacity are reviewed, presenting the general chemistry underlying the assays, the types of molecules detected, and the most important advantages and shortcomings of each method.
Journal ArticleDOI
Plant phenolics: extraction, analysis and their antioxidant and anticancer properties.
Jin Dai,Russell J. Mumper +1 more
TL;DR: The anticancer effects of phenolics in-vitro and in- vivo animal models are viewed, including recent human intervention studies, and possible mechanisms of action involving antioxidant and pro-oxidant activity as well as interference with cellular functions are discussed.
Journal ArticleDOI
Development and validation of an improved oxygen radical absorbance capacity assay using fluorescein as the fluorescent probe.
TL;DR: The improved ORAC(FL) assay provides a direct measure of hydrophilic chain-breaking antioxidant capacity against peroxyl radical and demonstrates that fluorescein (FL) is superior to B-phycoerythrin.
Journal ArticleDOI
Novel total antioxidant capacity index for dietary polyphenols and vitamins C and E, using their cupric ion reducing capability in the presence of neocuproine: CUPRAC method.
TL;DR: The development of a simple, widely applicable antioxidant capacity index for dietary polyphenols and vitamins C and E is reported, utilizing the copper(II)-neocuproine [Cu(II-Nc] reagent as the chromogenic oxidizing agent.
References
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Journal ArticleDOI
Use of a Free Radical Method to Evaluate Antioxidant Activity
TL;DR: The antiradical properties of various antioxidants were determined using the free radical 2,2-Diphenyl-1-picrylhydrazyl (DPPH*) in its radical form as discussed by the authors.
Journal ArticleDOI
A Novel Method for Measuring Antioxidant Capacity and its Application to Monitoring the Antioxidant Status in Premature Neonates
Nicholas J. Miller,Catherine Rice-Evans,Michael J. Davies,Vimala Gopinathan,Anthony D Milner +4 more
TL;DR: The method has been applied to investigate the total plasma antioxidant capacity of neonates and how this may be compromised in prematurity, and an antioxidant ranking was established based on their reactivity relative to a 1.0 mmol/l Trolox standard.
Journal ArticleDOI
Vegetables, Fruit, and Cancer Prevention: A Review
TL;DR: The evidence for a protective effect of greater vegetable and fruit consumption is consistent for cancers of the stomach, esophagus, lung, oral cavity and pharynx, endometrium, pancreas, and colon, and the types of vegetables or fruit that most often appear to be protective against cancer are raw vegetables.
Journal ArticleDOI
Lipid peroxidation: its mechanism, measurement, and significance.
Barry Halliwell,Susanna Chirico +1 more
TL;DR: An increased concentration of end products of lipid peroxidation is the evidence most frequently quoted for the involvement of free radicals in human disease, but it is likely that increased oxidative damage occurs in most, if not all, human diseases and plays a significant pathological role in only some of them.
Journal ArticleDOI
A procedure to measure the antiradical efficiency of polyphenols
TL;DR: In this article, the kinetic behavior of polyphenols common in fruits as free radical scavengers was studied using 2,2-diphenyl-1-picrylhydrazyl (DPPH).