Journal ArticleDOI
Antiprotozoal 4-aryloxy-2-aminoquinolines and related compounds.
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Journal ArticleDOI
Gold-Catalyzed Synthesis of Quinolines from Propargyl Silyl Ethers and Anthranils through the Umpolung of a Gold Carbene Carbon
Hongming Jin,Bin Tian,Xinlong Song,Jin Xie,Matthias Rudolph,Frank Rominger,A. Stephen K. Hashmi,A. Stephen K. Hashmi +7 more
TL;DR: This method offers a regiospecific and modular access to 2-aminoquinolines and other quinoline derivatives under mild conditions and with a broad functional-group tolerance.
Journal ArticleDOI
Cu(I)-catalyzed three component coupling protocol for the synthesis of quinoline derivatives
TL;DR: In this article, the synthesis of 2,4-disubstituted quinolines was achieved in a one-pot reaction from an aryl amine, an aldehyde and a terminal alkyne using CuCl (30 mol%) as a catalyst.
Journal ArticleDOI
Microwave-assisted simple synthesis of quinolines from anilines and alkyl vinyl ketones on the surface of silica gel in the presence of indium(III) chloride
TL;DR: In this article, a simple and efficient procedure for the synthesis of 4-alkylquinolines by a one-pot reaction of anilines with alkyl vinyl ketones on the surface of silica gel impregnated with indium(III) chloride under microwave irradiation without any solvent.
Journal ArticleDOI
Synthesis of Substituted Quinolines by the Electrophilic Cyclization of N-(2-Alkynyl)anilines
TL;DR: A wide variety of substituted quinolines are readily synthesized under mild reaction conditions by the 6-endo-dig electrophilic cyclization of N-(2-alkynyl)anilines by ICl, I(2), Br(2, PhSeBr and p-O(2)NC(6)H(4)SCl.
Journal ArticleDOI
Benign and highly efficient synthesis of quinolines from 2-aminoarylketone or 2-aminoarylaldehyde and carbonyl compounds mediated by hydrochloric acid in water
TL;DR: An environmentally friendly and highly efficient procedure for the preparation of substituted quinoline derivatives was developed by a simple Friedlander reaction of 2aminoarylketone or 2-aminoylaldehyde with carbonyl compounds in the presence of hydrochloric acid utilizing water as the solvent as discussed by the authors.