Journal ArticleDOI
Ascotoxin (Decumbin), a Metabolite of Ascochyta imperfecta PECK.
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In this article, the absolute structure of decumbin was presented as [II] by the following evidences: the configuration about C4 was determined as (S) by the benzoate rule on the tetrahydromonoketone (21).Abstract:
From the mycelium of Ascochyta imperfecta decumbin, C16H24O4, mp 203°C, was obtained in one percent yield.The absolute structure of decumbin was presented as [II] by the following evidences: The configuration about C4 was determined as (S) by the benzoate rule on the tetrahydromonoketone (21). The hydroxyl at C7 is α, because tetrahydrodecumbin (23) showed no intramolecular hydrogen bond, while its C7 epimer (24) did. Ring juncture was determined by ORD of a five membered ketone (16). Two double bonds were found to be trans from IR data. The stereochemistry of decumbin monoepoxide (7), tetrahydropyrans (12 and 13) was also studied. Plant tests of the twenty derivatives of decumbin on lucerne and rape revealed that the growth inhibition activity has close relation with the presence of double bond in the thirteen membered lactone ring.read more
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Antitumor and antiviral substances from fungi.
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Nematicidal substances from fungi.
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Bioactive Secondary Metabolites Produced by the Fungal Endophytes of Conifers.
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Structure of brefeldin A.
H. P. Weber,D. Hauser,H. P. Sigg +2 more
TL;DR: On the basis of X-ray crystal structure analysis, CD.
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Brefeldin A and α,β-dehydrocurvularin, two phytotoxins from Alternaria zinniae, a biocontrol agent of Xanthium occidentale
TL;DR: The interesting semi-selective toxicity to X. occidentale is described here, and the possible use of fungus and toxins in integrated weed management programs is discussed.
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Journal ArticleDOI
Über die Isolierung neuer Stoffwechselprodukte aus Penicillium brefeldianum DODGE
TL;DR: In this article, two new mold metabolites, Brefeldin A (C16H24O4) and Brefieldin B (C15H2205), have been isolated from the fermentation broth of a strain of Pefiicillium brefeldia from the DODGE.