Journal ArticleDOI
[Aspirin: Indications and use during pregnancy].
Reads0
Chats0
TLDR
L’efficacite de l’aspirine en prevention of the pre-eclampsie and du retard de croissance intra-uterin d’origine vasculaire a ete demontree chez les patientes a haut risque.Abstract:
Aspirin (acetylsalicylic acid) has been used ever since the Antiquity for its painkilling and anti-inflammatory effects. Its antiplatelet properties have then extended its indications to the field of coronaropathy and vascular cerebral disease, and finally to vascular placental disease. Aspirin has been widely prescribed since the 1980's to prevent pre-eclampsia, intra-uterine growth retardation and fetal death of vascular origin. It has also been proposed to prevent unexplained recurrent miscarriages. Its use during pregnancy is considered as safe, provided the daily doses do not exceed 100mg. Aspirin has been proven efficient to prevent pre-eclampsia and fetal growth restriction in high-risk patients. The benefits of prescribing aspirin have been demonstrated neither for vascular placental disease prevention in low risk patients, nor in cases of unexplained recurrent miscarriages.read more
Citations
More filters
Journal ArticleDOI
Over-the-counter analgesics during pregnancy: a comprehensive review of global prevalence and offspring safety.
TL;DR: The evidence of foetal exposure to OTC analgesia, starting from different routes of exposure to evidence, or the lack thereof, linking maternal consumption to offspring ill health is examined.
Journal ArticleDOI
Preterm birth after recurrent pregnancy loss: a systematic review and meta-analysis.
TL;DR: In this article , the authors evaluated the impact of recurrent pregnancy loss (RPL) on the risk of preterm birth (PTB) in subsequent pregnancies and found that women with a history of RPL had significantly higher odds of delivering preterm infants.
Journal ArticleDOI
Prévention de la pré-éclampsie en 2018 en population générale et chez la femme lupique : à l’aube d’une médecine personnalisée ?
C. De Moreuil,A.-L. Fauchais,Philippe Merviel,C. Tremouilhac,E. Le Moigne,Elisabeth Pasquier,Brigitte Pan-Petesch,Karine Lacut +7 more
TL;DR: In this paper, a pre-eclampsie was identified as a risk factor for pre-Eclampsia in femmes with pathologies vasculo-placentaires.
Iconographies supplémentaires de l'article : Prévention de la pré-éclampsie en 2018 en population générale et chez la femme lupique : à l’aube d’une médecine personnalisée ?
C. De Moreuil,A.-L. Fauchais,Philippe Merviel,C. Tremouilhac,E. Le Moigne,Elisabeth Pasquier,Brigitte Pan-Petesch,Karine Lacut +7 more
TL;DR: L’aspirine a prouve son efficacite en prevention primaire et secondaire de la pre-eclampsie, en particulier lorsqu’elle est donnee a la dose of 150 mg/jour au coucher avant 15 SA chez une population of patientes a haut risque.
Journal ArticleDOI
Clinical risk factors for vasculo-placental disorders: results from a prospective case-control study nested in HEMOTHEPP French cohort study.
Claire de Moreuil,B. Pan Petesch,C. Tremouilhac,Pierre François Dupre,Philippe Merviel,F Anouilh,Charles Bellot,M. A. Müller,G. Drugmanne,Emmanuel Nowak,Julien Coadic,Line Bihan,Lénaick Gourhant,Catherine A. Lemarié,Sara Robin,Francis Couturaud,Emmanuelle Le Moigne +16 more
TL;DR: In this paper , clinical risk factors for vasculo-placental disorders (pre-eclampsia, intrauterine growth restriction (IUGR), placental abruption or stillbirth) in singleton pregnancies were determined in a prospective case-control study nested in HEMOTHEPP French cohort.
References
More filters
Journal ArticleDOI
Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs
TL;DR: Experiments with guinea-pig lung suggest that some of the therapeutic effects of sodium salicylate and aspirin-like drugs are due to inhibition of the synthesis of prostaglandins.
Journal ArticleDOI
Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies
TL;DR: Factors that may be present at antenatal booking and the underlying evidence base can be used to assess risk at booking so that a suitable surveillance routine to detect pre-eclampsia can be planned for the rest of the pregnancy.
Journal ArticleDOI
Prevention of preeclampsia and intrauterine growth restriction with aspirin started in early pregnancy: a meta-analysis
Emmanuel Bujold,Stéphanie Roberge,Yves Lacasse,Marc Bureau,François Audibert,Sylvie Marcoux,Jean-Claude Forest,Yves Giguère +7 more
TL;DR: Low-dose aspirin initiated in early pregnancy is an efficient method of reducing the incidence of preeclampsia and intrauterine growth restriction and IUGR.
Journal ArticleDOI
Antiplatelet agents for prevention of pre-eclampsia: a meta-analysis of individual patient data
TL;DR: Antiplatelet agents during pregnancy are associated with moderate but consistent reductions in the relative risk of pre-eclampsia, of birth before 34 weeks' gestation, and of having a pregnancy with a serious adverse outcome.
Journal ArticleDOI
Placental Origins of Preeclampsia Challenging the Current Hypothesis
TL;DR: Although the placenta plays a crucial role in the development of preeclampsia, the onset, severity, and progression is significantly affected by the maternal response to placentally derived factors and proteins.