Asymmetric Michael addition of aldehydes to nitroalkenes using a primary amino acid lithium salt.
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The addition of aldehydes to nitroalkenes was successfully carried out by asymmetric catalysis with L-phenylalanine lithium salt, giving gamma-nitroaldehydes in good yields with high enantioselectivity.Abstract:
Enantioselective Michael addition of aldehydes to nitroalkenes was successfully carried out by asymmetric catalysis with L-phenylalanine lithium salt, giving γ-nitroaldehydes in good yields with high enantioselectivity.read more
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In the Golden Age of Organocatalysis
Peter I. Dalko,Lionel Moisan +1 more
TL;DR: The diverse examples show that in recent years organocatalysis has developed within organic chemistry into its own subdiscipline, whose "Golden Age" has already dawned.
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The advent and development of organocatalysis
TL;DR: My opinion on why the field of organocatalysis has blossomed so dramatically over the past decade is presented.
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Diphenylprolinol Silyl Ethers as Efficient Organocatalysts for the Asymmetric Michael Reaction of Aldehydes and Nitroalkenes
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Asymmetric Michael Additions to Nitroalkenes
TL;DR: In this paper, the asymmetric conjugate addition of various carbon and heteroatom nucleophiles to nitroalkenes as a tool for the construction of highly functionalized synthetic building blocks is presented.