Showing papers in "European Journal of Organic Chemistry in 2002"

TL;DR: In this paper, the asymmetric conjugate addition of various carbon and heteroatom nucleophiles to nitroalkenes as a tool for the construction of highly functionalized synthetic building blocks is presented.

TL;DR: The review covers the efforts made over the last decade towards designing efficient copper-catalysed systems for the asymmetric conjugate addition reaction.

TL;DR: The ring contraction of cyclic ketones has been explored by means of matrix isolation, time-resolved spectroscopy, and computation as discussed by the authors, and full retention of configuration of the migrating group has been established by using enantioselective chromatography.

TL;DR: In this paper, the authors focus on synthetic issues regarding shape-persistent cycles whose diameters range from a bit more than 1 nm up to the presently largest representative with approximately 5 nm.

TL;DR: This review gives an overview of the most widely utilized enzymes and the corresponding substrate profiles, together with applications in natural product and bioactive compound synthesis.

TL;DR: The aminopalladation-reductive elimination tandem reaction of internal and terminal alkynes containing proximate nitrogen nucleophiles has been proved to be a powerful and useful tool for the construction of the substituted pyrrole nucleus of the indole system as mentioned in this paper.

TL;DR: It is noteworthy that a variety of aldehydes, including hexanal, can be utilized for the current direct catalytic asymmetric aldol reaction, and the use of this new heteropolymetallic asymmetric catalyst has realized a diastereoselective and enantioselectives aldl reaction using cyclopentanone for the first time.

TL;DR: In this paper, the authors highlight recent progress in the synthetic methodologies leading to corroles and core-modified corroles, and focus is put on corroles with meso substituents.

TL;DR: In this article, the versatile carbene-like chemistry of electrophilic phosphinidene complexes (R−P=MLn) with C = C, C≡C, C=X, and X = N, O, S, Si, and P) bonds and aromatics is discussed.

TL;DR: A palladium-catalyzed cross-coupling reaction between arylboronic acids and mixed anhydrides, generated in situ from carboxylic acids and pivalic anhydride, is presented in this article.

TL;DR: In this paper, the authors present an asymmetric 1,4-addition to enones, catalyzed by cationic rhodium(I) complexes chelated with binap, MeO-biphep or josiphos ligand.

TL;DR: The thermal Claisen rearrangement of allyl vinyl ethers is generally regarded as high-performance method for diastereoselective C−C bond formation.

TL;DR: In this paper, the prepn. of trifluoromethyl substituted benzenes from iodobenzene and congeners was successfully extended to the pyridine series.

TL;DR: In this article, the Schmidt, Mitsunobu and DCC coupling procedures were used to obtain new C-10 ester and ether derivatives of the antimalarial drug dihydroartemisinin.

TL;DR: In this article, a linear solution-phase synthesis of the HIV-1 viral surface envelope glycoprotein gp120 highmannose nonasaccharide pentyl glycoside is described.

TL;DR: In this paper, a series of bis(phosphanes) (SP,SP′)-R1(Me)PCH2CH2P′R2R3 (1a−k; R1, R2, and R3 = 1-adamantyl, tert-butyl, cyclohexyl cyclopentyl, isopropyl, methyl, phenyl; abbreviated as unsymmetrical BisP*) has successfully been synthesized, by coupling of the (RP)-configured tosylates 5a−d or mes

TL;DR: In this article, a series of cascade condensations with 1,2-dicarbonyl compounds was used to obtain quantitative yields of heterocycles in solid-state syntheses that avoided waste formation.

TL;DR: In this paper, ten new hydrazino derivatives were synthesized, and their properties were studied by 1H and 13C NMR spectroscopy, including ring-chain tautomerism, cis-trans isomerism with respect to the substituents in the pyrazole ring, and (E)/(Z) rotamerism with relation to the nitrogen−carbon hydrazide bond with partial double-bond character.

TL;DR: In this article, the authors summarize the syntheses of optically active α- and γ-ionones (1, 3) and the epoxy and dihydro ionones 4−7.

TL;DR: In this article, the current status of the works on the direct metallation of pyridine derivatives with nBuLi/lithium aminoalkoxide aggregates is reviewed.

TL;DR: Several series of designed peptide antibiotics have been reported, as well as examples based on β-peptides and steroids, and many display potent antibacterial activity and selectivity for bacterial cells.

TL;DR: Despite the common perception that alkenes possessing electron-withdrawing groups are not adequate substrates for Pauson−Khand (PK) reactions, a number of successful examples of this reaction involving electron-deficient alkenses, such as α,β-unsaturated ketones, esters, nitriles, sulfoxides and sulfones, have been reported in recent years as discussed by the authors.

TL;DR: In this article, an ionic mechanism is proposed, where a nucleophilic attack of the oxygen lone-pair of the alcohol (or ether) onto the oxoammonium form of TEMPO (generated by laccase on oxidation) takes place leading to a transient adduct.

TL;DR: In this article, four analogues of cinchona alkaloids (5−8) lacking the quinoline nitrogen atom have been prepared, and phase transfer catalysts 10a, 10b, 11a, and 12d have been used.

TL;DR: Guanidinium-based compounds are biologically, medicinally, and pharmaceutically vital molecules as discussed by the authors, which are found in nature in numerous forms and can be synthesized using different methods.

TL;DR: In this article, the authors present a systematic study on the factors that determine the formation of a well-defined intramolecular H-bonding network between carbohydrate hydroxy groups, and its cooperative or anti-cooperative influence on selected intermolecular processes mediated by H bonds.

TL;DR: A macrocyclic neutral ionophore 8 (X = O) capable of binding weakly coordinating anions such as nitrate and bromide in DMSO solution has been designed by a stepwise, deductive approach as discussed by the authors.

TL;DR: In this paper, the Baylis-Hillman reaction of N-benzylidene-4-methylbenzenesulfonamide with methyl vinyl ketone (MVK) was investigated.

TL;DR: The chemistry of various salt forms of Oxone, an environmentally friendly oxidant, has been investigated in this article, showing that using purified reagents makes these reactions easier to workup and amenable to large scale synthesis because the amount of salt in the reaction has been greatly reduced.