Showing papers in "European Journal of Organic Chemistry in 2011"

TL;DR: In this paper, transition-metal-catalysed and -mediated processes for the preparation of oxindoles from anilides through C(3)-C(3a) bond formation are described.

TL;DR: A review of the approaches leading to a greener process are examined in detail, and the advances achieved to date in this important transformation are presented in this article, where a list of key research areas including the direct nucleophilic reactions of alcohols is established.

TL;DR: In this paper, the authors highlight the potential and the versatility of arenediazonium salts as viable alternatives to conventional aryl halides and oxygen-based electrophiles for Pd-catalyzed Heck reactions.

TL;DR: A review of successes and failures in the synthesis of small peptidomimetics that mimic the secondary structure of proteins under physiological conditions using copper- and ruthenium-catalysed Huisgen cycloaddition reactions.

TL;DR: Pd carbene migratory insertion was deemed to be the key step in a series of Pd-catalyzed reactions of diazo compounds, and the combination of this unique reaction and classic PcCatalyzed cross-coupling provides new potential for the development of novel PD- catalyzed transformations, in particular for C=C double bond formation.

TL;DR: A review of the development of the practical preparations of buckybowls, starting with the original synthesis of corannulene achieved in 1966, can be found in this paper, with a focus on the last decade developments which include construction of large, highly nonplanar molecular networks (molecular clips and tweezers) capable of binding guest molecules of various sizes and shapes.

TL;DR: In this paper, a microreview examines the recent advances in applying these two strategies for the functionalization of sp2 C-H bonds and is organized by the source of nitrogen atom.

TL;DR: Interference with the bacterial attachment to surfaces proves the vision of an antiadhesion therapy, among others, against uropathogenic E. coli (UPEC), and investigates the mannose-specific protein FimH, which is expressed on the tips of type 1 fimbriae.

TL;DR: This microreview summarizes important advances in the synthesis of fluorinated amino acids since 2005 and is divided into three groups on the basis of amino acid types: fluorinated α-amino acids (F-αAAs), fluorinated β-aminos acids (f-βAAs, and fluorinated cyclic amino acids ( F-CAAs).

TL;DR: In this article, the authors discuss recent achievements in developing enantioselective transformations by using catalysts derived from axially chiral binaphthyls: Bronsted acids (different from BINOL-phosphates), Lewis acids, and hydrogen-bond donors.

TL;DR: In this paper, an overview of recent progress in synthesizing fluoro-olefin compounds and some classical but still valuable synthetic reactions is presented. But the authors do not provide a detailed analysis of the synthesis process.

TL;DR: The major advances in the development of synthetic saccharide-based vaccines targeted against infectious diseases and cancer are reviewed.

TL;DR: The structural variety of naturally occurring diaryl ethers is illustrated and various synthetic methods employed for the construction of diary l ether linkages in related total syntheses are reviewed in this paper.

TL;DR: Iptycenes have wide applications in many research areas, including molecular machines, molecular balances, catalysis, materials chemistry, molecular assembly, host-guest chemistry, and so on.

TL;DR: In this paper, a family of thiazolium salt derived N-heterocyclic carbenes bearing sterically demanding aryl substituents on the nitrogen and with varying backbone substitution patterns have been synthesized.

TL;DR: In this article, a review of nucleophilic addition reactions of the CF3 carbanion to C=N bonds is presented, among which the major emphasis is placed on reactions using the Ruppert-Prakash reagent.

TL;DR: In this article, different chemical strategies were demonstrated for access to unsymetrically substituted porphyrin rings with nonequivalent β or meso substituents for optical limiting and photodynamic therapy.

TL;DR: In this article, a review of Au-catalyzed substitution reactions of unsaturated alcohols in which water serves as a leaving group is given, and the mechanisms by which the reactions are believed to occur are also reviewed.

TL;DR: The transition-metal-catalyzed chemoselective cross-coupling of arylbroronic acids in high yields without using ligand or base is reported here, and the products were obtained with high C–N coupling selectivity.

TL;DR: In this article, the spectral properties of the starting and final difluoroboron dipyrromethenes are discussed as a function of their structure, and a wide range of reactive 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene derivatives can be obtained.

TL;DR: In this paper, the authors highlight the unique role of water in the ring-opening reactions of epoxides and highlight the importance of water as a reaction medium for realizing processes that cannot be performed alternatively in other reaction media.

TL;DR: A review of α-alkylidene-substituted δ-lactones and corresponding γ- and δ lactams can be found in this paper, where the authors give a brief description of the occurrence and biological activities of the title compounds and then summarize the methods available for their preparation.

TL;DR: In this paper, a neutral intermediate pathway, involving carboxylic acid dimerization by mutual hydrogen bonding, was found to be accessible and may explain how the direct amide formation reaction occurs.

TL;DR: In this paper, the synthesis of spiro compounds through a Michael-Michael-aldol reaction was reported, which affords spiropyrazolone derivatives in good yields, in almost diastereo-and enantiopure form, and is catalyzed by diphenylprolinol derivatives.

TL;DR: The Ph3PAuNTf2-catalyzed cyclization of aryl propargyl ethers was applied as a key step to the concise synthesis of the naturally occurring benzopyrans seselin, xanthyletin, precocenes I and II, 8-(3′,3′-dimethylallyl)wenteria chromene, and 2,2-dimmethyl-8-prenylchromene-6-propenoic acid as mentioned in this paper.

TL;DR: An efficient protocol for copper-catalyzed C–S or C–Se bond formation between aryl iodides and easily available chalcogen sources leading to diaryl chalCogenides is reported, and was further successfully utilized for the synthesis of 2-phenylbenzo[b]thiophene and of [1]benzothieno[3,2-b].

TL;DR: The three-component reactions of aromatic aldehydes, arylamines, and acetylenedicarboxylates show very interesting molecular diversity as discussed by the authors, and the reaction mechanism for the formation of the three products is briefly explained.

TL;DR: In this article, case studies in natural product syntheses with comments on various aspects of metathesis reactions and on how the difficulties encountered in these syntheses have led to better understanding of these reactions or to more effective reaction conditions and catalysts.

TL;DR: The oxa-Pictet-spengler cyclization is the oxygen variation of the Pictet-Spengler reaction, in which an aromatic alcohol component (generally a β-arylethyl alcohol) reacts with an acarbonyl component (aldehyde, ketone or their masked derivatives), to yield a 1-substituted (or 1, 1,1′-disubstitized)pyran fused to the aromatic ring system found in the starting alcohol as discussed by the authors.

TL;DR: In this article, a series of 5-substituted 1H-tetrazoles were synthesized through cycloaddition reactions between nitriles RCN and NaN3 in the presence of Cu-Zn alloy nanopowder as catalyst.