Journal ArticleDOI
Atmospheric plasma enhances wettability and cell spreading on dental implant metals
Kathrin Duske,Ina Koban,Eckhard Kindel,Karsten Schröder,Barbara Nebe,Birte Holtfreter,Lukasz Jablonowski,Klaus D. Weltmann,Thomas Köcher +8 more
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TLDR
The application of cold plasma may be supportive in the treatment of peri-implant lesions and may improve the process of re-osseointegration.Abstract:
Objectives: Treatment regimens, which predictably support re-osseointegration of implants with peri-implantitis, are needed. Increased wettability may be an important factor for re-osseointegration. In this study, a cold atmospheric pressure gas-discharge plasma was applied to reduce water contact angles on titanium discs with different surface topography and to improve the spreading of osteoblastic cells. Material and Methods: An argon plasma jet with different oxygen admixtures was used to treat titanium discs with different topologies, i.e. machined, SLA ® , SLActive ® , diamond bur-treated or Airflow ® -treated. Water contact angles were measured before and after plasma treatment. The spreading behaviour of human osteoblastic cells was investigated. Results: Contact angle of titanium discs (baseline values: 68°–117°) were significantly reduced close to 0° irrespective of surface topography after the application of argon plasma with 1.0% oxygen admixture for 60 s or 120 s. The cell size of osteoblastic cells grown on argon-oxygen-plasma-treated titanium discs was significantly larger than on non-treated surfaces (p < 0.001) irrespective of surface topography. Conclusions: Plasma treatment reduced contact angle and supported spreading of osteoblastic cells. The application of cold plasma may be supportive in the treatment of peri-implant lesions and may improve the process of re-osseointegration.read more
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Plasmas for medicine
TL;DR: The aim of the new research field of plasma medicine is the exploitation of a much more differentiated interaction of specific plasma components with specific structural as well as functional elements or functionalities of living cells.
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A review on the wettability of dental implant surfaces II: Biological and clinical aspects
Rolando A. Gittens,Lutz Scheideler,Frank Rupp,Sharon L. Hyzy,Juergen Geis-Gerstorfer,Zvi Schwartz,Barbara D. Boyan +6 more
TL;DR: This review provides a general overview of the available information about the contact angle values of experimental and of marketed implant surfaces, some of the techniques used to modify surface wettability of implants, and results from in vitro and clinical studies.
Journal ArticleDOI
Surface characteristics of dental implants: A review.
TL;DR: Different height, spatial, hybrid and functional roughness parameters have been identified as possible candidates able to predict the outcome at hard and soft tissue interfaces and hydrophilic implants have been proven to improve the initial blood contact, to support the wound healing and thereby accelerating the osseointegration.
Journal ArticleDOI
A review on the wettability of dental implant surfaces I: theoretical and experimental aspects.
Frank Rupp,Rolando A. Gittens,Lutz Scheideler,Abraham Marmur,Barbara D. Boyan,Zvi Schwartz,Juergen Geis-Gerstorfer +6 more
TL;DR: The present study reviews the current knowledge on the wettability of biomaterial surfaces, encompassing basic and applied aspects that include measurement techniques, thermodynamic aspects of wetting and models predicting topographical and roughness effects on the wetting behavior.
References
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Journal ArticleDOI
Effect of titanium surface roughness on proliferation, differentiation, and protein synthesis of human osteoblast-like cells (MG63)
J. Y. Martin,Zvi Schwartz,Thomas W. Hummert,D. M. Schraub,J. Simpson,J. Lankford,David D Dean,David L. Cochran,Barbara D. Boyan +8 more
TL;DR: It is demonstrated that surface roughness alters osteoblast proliferation, differentiation, and matrix production in vitro and suggests that implant surfaceroughness may play a role in determining phenotypic expression of cells in vivo.
Journal ArticleDOI
Enhanced Bone Apposition to a Chemically Modified SLA Titanium Surface
Daniel Buser,Nina Broggini,Marco Wieland,Robert K. Schenk,Alain J. Denzer,David L. Cochran,B. Hoffmann,Adrian Lussi,S. G. Steinemann +8 more
TL;DR: It is concluded that the modSLA surface promoted enhanced bone apposition during early stages of bone regeneration, as compared with a standard SLA surface.
Journal ArticleDOI
High surface energy enhances cell response to titanium substrate microstructure.
Ge Zhao,Zvi Schwartz,Marco Wieland,Frank Rupp,Jürgen Geis-Gerstorfer,David L. Cochran,Barbara D. Boyan +6 more
TL;DR: Osteoblasts grown on modified Ti surfaces exhibited a more differentiated phenotype characterized by increased alkaline phosphatase activity and osteocalcin and generated an osteogenic microenvironment through higher production of PGE2 and TGF-beta1 and 1alpha,25OH2D3 increased these effects in a manner that was synergistic with high surface energy.
Journal ArticleDOI
Surface modification of polymers for medical applications.
TL;DR: This review article focuses on the surface modification of polymers by grafting techniques, which have long been known in polymer chemistry but are not yet widely applied to biomaterials.
Journal ArticleDOI
Comparison of Direct and Indirect Effects of Non‐Thermal Atmospheric‐Pressure Plasma on Bacteria
Gregory Fridman,Ari D. Brooks,Manjula Balasubramanian,Alexander Fridman,Alexander Gutsol,Victor N. Vasilets,Halim Ayan,Gary Friedman +7 more
TL;DR: It is demonstrated that direct influence of the plasma, where charged particles contact bacteria directly, produces inactivation much faster than the indirect treatment, where plasma afterglow is delivered to the bacteria with a gas flow through the plasma region.