Journal ArticleDOI
Automated liquid chromatography. Synthesis of a broad-spectrum resolving agent and resolution of 1-(1-naphthyl)-2,2,2-trifluoroethanol
W. H. Pirkle,M. S. Hoekstra +1 more
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This article is published in Journal of Organic Chemistry.The article was published on 1974-12-01. It has received 116 citations till now. The article focuses on the topics: Resolution (mass spectrometry).read more
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Chromatographische Racemattrennung von Thalidomid und teratogene Wirkung der Enantiomere
TL;DR: Racemic thalidomide is chromatographically separated on optically active polyamide giving both enantiomers, and after i.p. administration only the S-(-)-enantiomer is teratogenic on SWS mice and Natal rats.
Journal ArticleDOI
Chromatographic Resolution of Racemates. New analytical methods (17)
TL;DR: In this paper, a number of racemates can be resolved into optically pure enantiomers by chromatography on optically active adsorbents, such as amide, amino acid, and crown ether groups.
Journal ArticleDOI
Stereochemical difference between 12-hydroxy-5,8,10,14-eicosatetraenoic acid in platelets and psoriatic lesions.
TL;DR: The 'psoriasis derived' compound was shown to be stereochemically distinct from the platelet 12(S)-enantiomer as its derivative co-chromatographed with the 12(R)-diastereomer.
Related Papers (5)
Trichlorosilane induced cleavage. A mild method for retrieving carbinols from carbamates
W. H. Pirkle,J. R. Hauske +1 more