Open AccessJournal Article
Barrett's esophagus: congenital or acquired? An experimental study of esophageal mucosal regeneration in the dog.
Bremner Cg,Lynch Vp,Ellis Fh +2 more
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These experiments support the concept that the columnar-lined distal esophagus ("Barrett's Esophagus") may be an acquired condition in which squamous epithelium destroyed by gastroesophageal reflux is replaced, through creeping substitution, by columnar cells of gastric or junctional origin.About:
This article is published in Surgery.The article was published on 1970-07-01 and is currently open access. It has received 348 citations till now. The article focuses on the topics: Barrett's esophagus & Esophagus.read more
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British Society of Gastroenterology guidelines on the diagnosis and management of Barrett's oesophagus
Rebecca C. Fitzgerald,Massimiliano di Pietro,Krish Ragunath,Yeng Ang,Jin-Yong Kang,Peter H. Watson,Nigel Trudgill,Praful Patel,Philip Kaye,Scott Sanders,M O'Donovan,Elizabeth L. Bird-Lieberman,Pradeep Bhandari,Janusz Jankowski,Stephen Attwood,Simon L. Parsons,Duncan Loft,Jesper Lagergren,Paul Moayyedi,Georgios Lyratzopoulos,John de Caestecker +20 more
TL;DR: These guidelines provide a practical and evidence-based resource for the management of patients with Barrett's oesophagus and related early neoplasia and suggested stratification of patients according to their estimated cancer risk based on clinical and histopathological criteria for the first time.
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Barrett's esophagus: A prevalent, occult complication of gastroesophageal reflux disease
Charles Winters,Timothy J. Spurling,Sarkis J. Chobanian,David J. Curtis,Regina L. Esposito,Joseph F. Hacker,David A. Johnson,David F. Cruess,James D. Cotelingam,Michael S. Gurney,Edward L. Cattau +10 more
TL;DR: A prospective study of patients with symptoms of gastroesophageal reflux was undertaken to determine the prevalence of Barrett's esophagus and reevaluate the diagnostic approach necessary to detect this complication.
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Columnar-lined lower esophagus: an acquired lesion with malignant predisposition. Report on 140 cases of Barrett's esophagus with 12 adenocarcinomas.
TL;DR: The analysis of a series of 1,225 cases of reflux esophagitis shows the serious nature of this condition and the transition toward malignancy seems to be irreversible and cannot be arrested by an antireflux operation, so repeated esophageal controls and biopsies are an absolute necessity.
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Gastroesophageal reflux, Barrett esophagus, and esophageal cancer. Scientific review
TL;DR: Strong evidence supports the association of GERD and adenocarcinoma of the esophagus; however, the risk of cancer in any given individual with GERD is low and insufficient evidence exists to endorse routine endoscopic screening of patients with chronic GERD symptoms.
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Barrett's esophagus: Age, prevalence, and extent of columnar epithelium
TL;DR: The development of Barrett's esophagus was studied using data from 51,311 patients undergoing upper gastrointestinal endoscopy between 1976 and 1989 and the data are consistent with a fairly rapid evolution to its full length with little subsequent change.