Journal ArticleDOI
Brain stem responses evoked by stimulation with an auditory brain stem implant in children with cochlear nerve aplasia or hypoplasia.
Martin O'Driscoll,Wael El-Deredy,Ahmet Ataş,Gonca Sennaroglu,Levent Sennaroglu,Richard T. Ramsden +5 more
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TLDR
The presence of an intraoperative EABR was a good indicator for the location of electrodes on the ABI array that provided auditory sensations and could be used to assist with initial device fitting, while Behavioral T and C levels showed a good correlation with postoperative EabR thresholds but a poor correlation with intraoperativeEABR thresholds.Abstract:
OBJECTIVES: The inclusion criteria for an auditory brain stem implant (ABI) have been extended beyond the traditional, postlingually deafened adult with Neurofibromatosis type 2, to include children who are born deaf due to cochlear nerve aplasia or hypoplasia and for whom a cochlear implant is not an option. Fitting the ABI for these new candidates presents a challenge, and intraoperative electrically evoked auditory brain stem responses (EABRs) may assist in the surgical placement of the electrode array over the dorsal and ventral cochlear nucleus in the brain stem and in the postoperative programming of the device. This study had four objectives: (1) to characterize the EABR by stimulation of the cochlear nucleus in children, (2) to establish whether there are any changes between the EABR recorded intraoperatively and again just before initial behavioral testing with the device, (3) to establish whether there is evidence of morphology changes in the EABR depending on the site of stimulation with the ABI, and (4) to investigate how the EABR relates to behavioral measurements and the presence of auditory and nonauditory sensations perceived with the ABI at initial device activation. DESIGN: Intra- and postoperative EABRs were recorded from six congenitally deaf children with ABIs, four boys and two girls, mean age 4.2 yrs (range 3.2 to 5.0 yrs). The ABI was stimulated at nine different bipolar sites on the array, and the EABRs recorded were analyzed with respect to the morphology and peak latency with site of stimulation for each recording session. The relationship between the EABR waveforms and the presence or absence of auditory electrodes at initial device activation was investigated. The EABR threshold levels were compared with the behavioral threshold (T) and comfortably loud (C) levels of stimulation required at initial device activation. RESULTS: EABRs were elicited from all children on both test occasions. Responses contained a possible combination of one to three peaks from a total of four identifiable peaks with mean latencies of 1.04, 1.81, 2.61, and 3.58 msecs, respectively. The presence of an EABR was a good predictor of an auditory response; however, the absence of the EABR was poor at predicting a site with no auditory response. The morphology of EABRs often varied with site of stimulation and between EABR test occasions. Postoperatively, there was a trend for P1, P3, and P4 to be present at the lateral end of the array and P2 at the medial end of the array. Behavioral T and C levels showed a good correlation with postoperative EABR thresholds but a poor correlation with intraoperative EABR thresholds. CONCLUSIONS: The presence of an intraoperative EABR was a good indicator for the location of electrodes on the ABI array that provided auditory sensations. The morphology of the EABR was often variable within and between test sessions. The postoperative EABR thresholds did correlate with the behavioral T and C levels and could be used to assist with initial device fitting.read more
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Journal ArticleDOI
Auditory responses to electric and infrared neural stimulation of the rat cochlear nucleus.
Rohit U. Verma,Amélie A. Guex,Kenneth E. Hancock,Nedim Durakovic,Colette M. McKay,Michaël C.C. Slama,M. Christian Brown,M. Christian Brown,Daniel J. Lee +8 more
TL;DR: For deaf individuals who use the auditory brainstem implant, INS alone did not appear promising as a new approach, consistent with a reported "optophonic" effect, a laser-induced acoustic artifact.
Journal ArticleDOI
Systematic Review of Nontumor Pediatric Auditory Brainstem Implant Outcomes
Kimberley S. Noij,Kimberley S. Noij,Elliott D. Kozin,Elliott D. Kozin,Rosh K. V. Sethi,Rosh K. V. Sethi,Parth V. Shah,Parth V. Shah,Alyson Kaplan,Alyson Kaplan,Barbara S. Herrmann,Barbara S. Herrmann,Aaron K. Remenschneider,Aaron K. Remenschneider,Daniel J. Lee,Daniel J. Lee +15 more
TL;DR: ABI surgery is a reasonable option for the habilitation of deaf children who are not cochlear implant candidates but pediatric ABI users with nonauditory disabilities have inferior audiometric outcomes.
Journal ArticleDOI
New outcomes with auditory brainstem implants in NF2 patients.
Robert Behr,Vittorio Colletti,Cordula Matthies,Akio Morita,Hirofumi Nakatomi,Liguoro Dominique,Vincent Darrouzet,Stefan Brill,Wafaa Shehata-Dieler,Artur Lorens,Henryk Skarżyński +10 more
TL;DR: The consensus opinion was that brainstem trauma is a primary factor in the variability of outcomes in NF2 patients, and ABI surgery should be accomplished with great care to minimize physical and venous trauma to the brainstem.
Journal ArticleDOI
Cochlear implantation in children with cochlear nerve deficiency: a report of nine cases.
TL;DR: The decision to perform cochlear implantation in children with coChlear nerve deficiency must be undertaken with caution as it has limited effectiveness and uncertain cost-benefit.
Journal ArticleDOI
Initial Results of a Safety and Feasibility Study of Auditory Brainstem Implantation in Congenitally Deaf Children.
Eric P. Wilkinson,Laurie S. Eisenberg,Mark D. Krieger,Marc S. Schwartz,Margaret Winter,Jamie L. Glater,Amy S. Martinez,Laurel M. Fisher,Robert V. Shannon +8 more
TL;DR: ABI surgery and device activation seem to be safe and feasible in this preliminary cohort of congenitally deaf children and the children are demonstrating some ability to discriminate between closed-sets words that differ by number of syllables (pattern perception).
References
More filters
Proceedings ArticleDOI
A robust and scalable clustering algorithm for mixed type attributes in large database environment
TL;DR: A distance measure is proposed that enables clustering data with both continuous and categorical attributes and is derived from a probabilistic model that the distance between two clusters is equivalent to the decrease in log-likelihood function as a result of merging.
Journal ArticleDOI
The relationship between EAP and EABR thresholds and levels used to program the nucleus 24 speech processor: data from adults.
Carolyn J. Brown,Michelle L. Hughes,Betty Luk,Paul J. Abbas,Abigail Wolaver,Jonathan P. Gervais +5 more
TL;DR: Either EAP or EABR thresholds can be used in combination with a limited amount of behavioral information to predict MAP T‐ and C‐levels with reasonable accuracy.
Journal ArticleDOI
Multichannel auditory brainstem implant: update on performance in 61 patients
Steven R. Otto,Derald E. Brackmann,William E. Hitselberger,Robert V. Shannon,Johannes Kuchta +4 more
TL;DR: The multichannel ABI proved to be effective and safe in providing useful auditory sensations in most patients with NF2 and improved patients' ability to communicate compared with the lipreading-only condition.
Journal ArticleDOI
Open set speech perception with auditory brainstem implant
TL;DR: Only a small percentage of auditory brainstem implant (ABI) recipients treated for neurofibromatosis type 2 (NF2) have proved capable of identifying words using only the sound from the ABI.
Journal ArticleDOI
Time course of axonal myelination in the human brainstem auditory pathway
TL;DR: The cotemporality in appearance of myelin, reflex responses, and evoked responses supports the idea that the 26th to 28th gestational weeks are a critical period in the onset of human central auditory function.