Journal ArticleDOI
Cardiovascular effects of oxytocic drugs used post partum
TLDR
The use of oxytocin and/or ergot drugs post partum for the prevention of or the control of postpartum hemorrhage and the relatively longer hypertension following administration of ergonovine and methylergonovines maleate have been demonstrated in human subjects.About:
This article is published in American Journal of Obstetrics and Gynecology.The article was published on 1970-11-01. It has received 105 citations till now. The article focuses on the topics: Methylergonovine Maleate & Ergonovine.read more
Citations
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Journal ArticleDOI
Induction of labor
TL;DR: Several systematic reviews with meta-analyses have shown that prostaglandins are superior to placebo and oxytocin alone in ripening of the cervix and the most appropriate dose and route of administration has not yet been confirmed.
Journal ArticleDOI
Induction of Labour
Dean Leduc,Anne Biringer,Lily Lee,Jessica Dy,Thomas Corbett,Louise Duperron,Ian Lange,Suzanne Muise,Barbara Parish,Lexy Regush,Kathi Wilson,Grace Yeung,Joan Crane,Robert Gagnon,Diane Sawchuck,Vyta Senikas +15 more
TL;DR: The most current literature is reviewed to provide evidence-based recommendations to obstetrical care providers on induction of labour and appropriate timing and method of induction, appropriate mode of delivery, and optimal maternal and perinatal outcomes.
Journal ArticleDOI
Haemodynamic effects of oxytocin given as i.v. bolus or infusion on women undergoing Caesarean section
TL;DR: It is recommended that bolus doses should be used with caution, and further studies should ascertain if oxytocin is equally effective in reducing blood loss when given at a slower rate.
Journal ArticleDOI
Human vascular endothelial cells express oxytocin receptors.
Marc Thibonnier,Doreen M. Conarty,Judy A. Preston,Christine L. Plesnicher,Raed A. Dweik,Serpil C. Erzurum +5 more
TL;DR: Human vascular ECs express OT receptors that are structurally identical to the uterine and mammary OT receptors, and these endothelial OT receptors produce a calcium-dependent vasodilatory response via stimulation of the nitric oxide pathway and have a trophic action.
Journal ArticleDOI
The effects of routine oxytocic administration in the management of the third stage of labour: an overview of the evidence from controlled trials
TL;DR: Data derived from nine published reports of controlled trials in which an oxytocic drug was compared with either a placebo or no routine prophylactic shows that routine active management of the third stage of labour increases rather than decreases maternal and neonatal morbidity.
References
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Journal ArticleDOI
On some physiological actions of ergot.
TL;DR: The facts make it impossible to speak of the action any longer as that of chrysotoxin, as the introduction of new names on the strength of physiological results, and in default of chemical isolation of principles, would inevitably add to the existing confusion.
Journal ArticleDOI
The sequence of amino acids in oxytocin, with a proposal for the structure of oxytocin.
TL;DR: A tentative structure for oxytocin is proposed on the basis of data derived from utilization of the Edman degradation and from the cleavage with bromine water.
Journal Article
A quantitative study of the action of synthetic oxytocin on the pregnant human uterus.
R. Caldeyro-Barcia,Y. Sica-Blanco,J.J. Poseiro,V. Gonzalez Panizza,C. Méndez-Bauer,C. Fielitz,Alvarez H,S. V. Pose,C. H. Hendricks +8 more
TL;DR: In this article, an exponential relation was found between the oxytocin infusion rate (inf) and the increase (ΔUA) of uterine activity produced by the infusion, where ΔUA is the maximum increase of the uterus activity which should be produced when inf increases infinitely.
Journal ArticleDOI
A quantitative study of the action of synthetic oxytocin on the pregnant human uterus
R. Caldeyro-Barcia,Y. Sica-Blanco,J.J. Poseiro,V. Gonzalez Panizza,C. Méndez-Bauer,C. Fielitz,Alvarez H,S. V. Pose,C. H. Hendricks +8 more
TL;DR: In normal pregnant women at term the infusion of oxytocin at the rates of 1 and 8 mU/min respectively, increases uterine activity to values similar to those recorded at the beginning and at the end of the first stage of normal spontaneous labor.
Journal ArticleDOI
The action of ergot preparations on the puerperal uterus: a clinical investigation with special reference to an active constituent of ergot as yet unidentified.
J. Chassar Moir,H. H. Dale +1 more
TL;DR: All adhesions were divided, and the child returned to bed in good condition, and a year later the child was in good health, plump, _onny, and free from symptoms, and had gained over a stone in weight.
Related Papers (5)
Haemodynamic Effects of Oxytocin (Syntocinon®) and Methyl Ergometrine (Methergin®) on the Systemic and Pulmonary Circulations of Pregnant Anaesthetized Women
N. J. Secher,P. Arnsbo,L. Wallin +2 more