Journal ArticleDOI
Catecholamines and methyltransferases in the South American toad (Bufo marinus).
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This article is published in Biochimica et Biophysica Acta.The article was published on 1962-04-09. It has received 36 citations till now. The article focuses on the topics: Toad.read more
Citations
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Journal ArticleDOI
Further classification of skin alkaloids from neotropical poison frogs (dendrobatidae), with a general survey of toxic/noxious substances in the amphibia
TL;DR: Cutaneous granular glands are a shared character of adult amphibians, including caecilians, and are thought to be the source of most biologically active compounds in amphibian skin, which clearly prove the defensive value of these diverse metabolites.
Journal ArticleDOI
Cutaneous granular glands and amphibian venoms
R.C. Toledo,Carlos Jared +1 more
TL;DR: The first amphibians were able to spend longer periods in a terrestrial environment through gradual acquisition of a set of adaptations, both morphofunctional and behavioural, and the multicellular exocrine glands of the skin represent one such adaptation.
Journal ArticleDOI
Toxicity of Panamanian poison frogs (Dendrobates): some biological and chemical aspects
John W. Daly,Charles W. Myers +1 more
TL;DR: A small Neotropical frog, Dendrobates pumilio, undergoes interpopulational variation in color, degree of toxicity, size, and habits, which may result from isolation and chance restriction of original heterozygosity, with subsequent selection acting on different and greatly limited mixtures of alleles.
Journal ArticleDOI
Purification and properties of bovine phenylethanolamine N-methyltransferase.
TL;DR: Kinetic measurements indicated a complex reaction mechanism which is best described as a random binding of substrates with S-adenosylmethionine being kinetically preferred as the first substrate bound.
Book ChapterDOI
The Distribution of Catecholamines in Vertebrates
TL;DR: Three catecholamines have been definitely identified as being present in many vertebrate tissues and the presence of the precursor amino acid L-DOPA is definitely identified.
References
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Journal ArticleDOI
Enzymatic O-methylation of epinephrine and other catechols.
Julius Axelrod,Robert Tomchick +1 more
TL;DR: The properties of an enzyme that transfers the methyl group of S-adenosylmethionine to the hydroxyl group in position 3 of epinephrine and other catechols are described.
Journal ArticleDOI
The chemical estimation of adrenaline-like substances in blood.
H. Weil-Malherbe,A. D. Bone +1 more
Journal ArticleDOI
Purification and properties of hydroxyindole-O-methyl transferase.
Julius Axelrod,Herbert Weissbach +1 more
Journal ArticleDOI
The distribution and properties of a histamine-methylating enzyme.
Journal ArticleDOI
Enzymatic Formation of Psychotomimetic Metabolites from Normally Occurring Compounds
TL;DR: An enzyme has been found that N-methylates serotonin and tryptamine to psychotomimetic metabolites, bufotenine and N,N-dimethyltryptamine.