Cefoxitin resistance mediated by loss of a porin in clinical strains of klebsiella pneumoniae and escherichia coli
S Ananthan,A Subha +1 more
Reads0
Chats0
TLDR
OMP analysis revealed that cefoxitin and ceftazidime resistance was mediated by loss of a porin Omp K35 in the isolates of K.pneumoniae and E.coli.About:
This article is published in Indian Journal of Medical Microbiology.The article was published on 2005-01-01 and is currently open access. It has received 83 citations till now. The article focuses on the topics: Porin & Cefoxitin.read more
Citations
More filters
Journal ArticleDOI
Mechanisms of Antimicrobial Resistance in Bacteria
TL;DR: 3 case histories-one involving Escherichia coli resistance to third-generation cephalosporins, another focusing on the emergence of vancomycin-resistant Staphylococcus aureus, and a third detailing multidrug resistance in Pseudomonas aeruginosa--are reviewed to illustrate the varied ways in which resistant bacteria develop.
Journal ArticleDOI
Breakthroughs in bacterial resistance mechanisms and the potential ways to combat them.
TL;DR: A wide range of approaches like developing new generations of antibiotics, combination therapy, natural antibacterial substances and applying nanoparticulate systems have been explained, among them, antibiotic delivery via nanoparticles, has been attracted more attention recently, so discussed in present review.
Journal Article
Occurrence of ESBL & Amp-C beta-lactamases & susceptibility to newer antimicrobial agents in complicated UTI.
TL;DR: A prospective study to know the occurrence of ESBL and AmpC producing strains and their antibiotic susceptibilities to newer agents to guide empirical therapy for complicated urinary tract infections finds a test using discs containing pipersacillin and piperacillin-tazobactam at a distance of 20 mm would act as a useful screening procedure for AmpC production.
Journal ArticleDOI
Characterization of Multidrug Resistant Extended-Spectrum Beta-Lactamase-Producing Escherichia coli among Uropathogens of Pediatrics in North of Iran.
Mohammad Sadegh Rezai,Ebrahim Salehifar,Alireza Rafiei,Taimour Y. Langaee,Mohammadreza Rafati,Kheironesa Shafahi,Gohar Eslami +6 more
TL;DR: In conclusion, carbapenems were the most effective antibiotics against ESBl-producing E. coli in urinary tract infection in North of Iran.
Journal ArticleDOI
PER, CTX-M, TEM and SHV Beta-lactamases in Clinical Isolates of Klebsiella pneumoniae Isolated from Tehran, Iran
TL;DR: The aim of this study was to determine the prevalence of blaSHV, blaTEM ,blaPER and blaCTX genes among clinical K. pneumoniae of different hospitals in Tehran and to recommend simple test based on CLSI recommendation for confirming ESBL production in enterobacterial species.
References
More filters
Journal ArticleDOI
Antibiotic susceptibility testing by a standardized single disk method.
TL;DR: Recommendations of the National Committee for Clinical Laboratory Standards continue to be based on this publication; the “Kirby-Bauer” method is, among the many disk methods used in other countries, still the one that has been researched most thoroughly and updated continuously.
Journal ArticleDOI
Solubilization of the Cytoplasmic Membrane of Escherichia coli by the Ionic Detergent Sodium-Lauryl Sarcosinate
TL;DR: In this paper, the sensitivity of the outer and cytoplasmic membranes of Escherichia coli to detergent was examined by isopycnic sucrose density gradient centrifugation.
Journal ArticleDOI
Occurrence and Detection of AmpC Beta-Lactamases among Escherichia coli, Klebsiella pneumoniae, and Proteus mirabilis Isolates at a Veterans Medical Center
TL;DR: A three-dimensional extract test was described, which was used to detect phenotypically isolates that harbor AmpC beta-lactamase, and confirmed that, at this institution, E. coli, K. pneumoniae, and P. mirabilis harbor plasmid-mediated AmpC enzymes.
Journal ArticleDOI
Roles of β-Lactamases and Porins in Activities of Carbapenems and Cephalosporins against Klebsiella pneumoniae
Luis Martínez-Martínez,Álvaro Pascual,Santiago Hernández-Allés,Dolores Alvarez-Díaz,A I Suárez,John H. Tran,Vicente J. Benedí,George A. Jacoby +7 more
TL;DR: Porin loss can augment resistance provided either by TEM- or SHV-type ESBLs or by plasmid-mediated AmpC enzymes to include the latest oxyimino-β-lactams and carbapenems in K. pneumoniae.
Journal ArticleDOI
In vivo selection of porin-deficient mutants of Klebsiella pneumoniae with increased resistance to cefoxitin and expanded-spectrum-cephalosporins.
Luis Martínez-Martínez,S Hernández-Allés,Sebastián Albertí,Juan M. Tomás,V J Benedi,George A. Jacoby +5 more
TL;DR: It is concluded that the increased resistance to cefoxitin and expanded-spectrum cephalosporins of isolate LB4 was due to loss of a porin channel for antibiotic uptake.