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Álvaro Pascual
Researcher at Spanish National Research Council
Publications - 496
Citations - 19476
Álvaro Pascual is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Klebsiella pneumoniae & Acinetobacter baumannii. The author has an hindex of 64, co-authored 471 publications receiving 17375 citations. Previous affiliations of Álvaro Pascual include Utrecht University & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
Quinolone resistance from a transferable plasmid
TL;DR: Although resistance was low in wild-type strains, higher levels of quinolone resistance arose readily by mutation, suggesting that a multiresistance plasmid can speed the development and spread of resistance to these valuable antimicrobial agents.
Journal ArticleDOI
Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: The CREATE-ECLA randomized controlled trial
Shamir R. Mehta,Salim Yusuf,Rafael Diaz,Jun Zhu,Prem Pais,Denis Xavier,Ernesto Paolasso,Rashid J. Ahmed,Changchun Xie,Khawar Kazmi,Javed Tai,Andrés Orlandini,Janice Pogue,Lisheng Liu,L. Cronin,Rakesh Gupta,K. K. Haridas,T. M. Jaison,Prashant P. Joshi,Prafulla Kerkar,A. K. Maity,S. C. Manchanda,Sudhir Naik,Dorairaj Prabhakaran,Seemala Saikrishna Reddy,Bateshwar Prasad Singh,S. Thanikachalam,D. Xavier,X. J. Bai,T. Chen,J. J. Cui,T. X. Cui,S. Y. Fu,H. Ge,Q. L. Li,S. M. Li,W. Li,Y. Q. Li,L. Liu,Y. H. Liu,Z. R. Lu,S. P. Ma,D. Qiao,Y. C. Song,N. L. Sun,L. H. Wang,S. W. Wang,W. Wang,Y. Wang,N. Wu,Y. S. Wu,C. B. Xu,S. C. Xu,Z. M. Xu,G. J. Yang,H. S. Yang,C. Z. Zhang,S. T. Zhang,W. J. Zhang,J. C. Zhou,J. Zhu,Wael Almahmeed,Alvaro Avezum,P. Castro,Ramón Corbalán,R. Pitarch Flors,B. M. Lombana,L. Marano,Darren K. McGuire,E. Paolasso,J. E. Isea Perez,L. Soares Piegas,F. Van de Werf,Harvey D. White,Mohammad Zubaid,A. M. Faruqi,I. Rasool,K. Soomro,H. ul Banna,S. Yusuf,S. R. Mehta,R. J. Ahmed,S. Pavlov,J. Pogue,F. Zhao,I. Tsuluca,M. Molec,I. Holadyk-Gris,K. Ahmed,P. Pais,D. Freeda,S. Lidwin,M. Chenniappan,B. Isaac,S. S. Iyengar,Pradeep Joshi,Shriprakash Kalantri,Susmita Kaushik,U. K. Mahorkar,J. Narendra,Sanjoy K. Paul,M. J. Santhosh,B. K.S. Sastry,S. B. Siwach,K. Varghese,H. Yang,Y. Yang,X. Zhang,H. Tan,J. Tang,X. Li,L. Yan,Y. Zhang,J. Li,M. Y. Bai,Y. Q. Jiang,S. Y. Lang,X. Y. Shi,Z. R. Tian,K. Wang,D. H. Yan,S. Y. Yu,Álvaro Pascual,H. Ozcoidi,Carmen de la Cuesta,D. Wojdyla,G. M. Font,M. I. Genisans,I. Chandna,M. Rafiq,N. Dadani,S. S. Fatima,S. Rehman,S. Adil,K. Bhojomal,Abdul Hameed,S. A. Khan,P. Sleight,C. Baigent,Jack Hirsh,W. Taylor,G. Tognoni,P. Bacher,N. Bender,U. Legler,U. Magin,U. Raschke,M. San Mauro,M. A. Brito,A. Alves De Lima,R. A. Ahuad Guerrero,R. Nordaby,R. J. Barcudi,J. Bono,R. E. Ledesma,H. R. Ramos,A. Caccavo,S. M. Macin,S. N. Ferreyra Cantante,G. D. Caime,L. R. Cartasegna,O. A. Perrino,A. J. Gambarte,E. Marzetti,M. Garrido,R. J. Balado,Cláudia B.R. Martinez,A. A. Fernandez,E. Ferro Queirel,J. O. Balbi,G. Amuchastegui,G. Covelli,A. Gentile,C. E. Girino,Job E. Lopez,R. Monti,A. D. Orlandini,O. Pellizon,J L Ramos,G. Zapata,C. A. Cuneo,J. A. Sanchez,J. P. Albisu,M. A. Berli,M. A. Hominal,R. A. Peleteiro Mariño,V. Mezzina,E. M. Avila,P. Baselga,C. R. Castellanos,H. L. Luciardi,L. L. Lobo Marquez,J. Muntaner,E. M. Good God,G. Reis,D. M. Mello Soares,Luiz Carlos Bodanese,E. Manenti,L. Prestes,J. G. De Castro Amino,R. Uchoa Azevedo,Antonio Carlos Carvalho,R. F. Ramos,M. Alcaino,P. Castro Galvez,R. Corbalán Herreros,H. Liu,R. Wang,Z. C. Liu,X. Tian,G. Wang,Z. Nan,J. Zhang,C. Zai,W. Chen,M. Gao,D. Hu,S. Jia,D. X. Li,Q. Li,S. L. Liu,Y. Sun,B. Wang,G. F. Xie,Z. Xu,X. Yang,M. Zhao,X. Zhao,Z. Fang,S. Y. Liu,Z. Ma,Y. Jiang,Z. Zhen,F. Huo,H. G. Yang,Y. Miao,C. M. Yang,X. Chi,Z. X. Liu,S. Zhou,F. S. Zhou,R. Guo,K. Jing,S. Ren,J. Zhao,H. Bai,C. Cheng,J. Cheng,X. Hao,H. Li,W. G. Li,S. Wang,W. Zhang,L. Li,S. Fu,J. Shao,X. Tan,S. Chen,J. Fu,Q. Zheng,J. Ma,H. Chen,H. Ma,L. Gong,Z. Zhang,F. Li,B. Yang,L. S. Zhou,Z. Wang,X. Sun,G. Tao,Q. Wang,X. Guo,X. Wang,K. Zai,Q. Cui,S. Fan,W. Liu,Q. Meng,G. Qi,Y. Qin,N. Wang,G. Xu,X. Yin,Q. Zhang,S. Zhang,R. Liu,F. Wang,W. K. Li,H. Zhang,X. Xu,R. Ma,F. Guan,T. Yang,R. Zhqo,J. Huang,A. Li,J. Zhou,X. You,L. Hao,F. Zhangfang,X. Ma,C. Shen,Z. Hou,N. F. Zho,G. Huang,P. Guo,J. Lou,Q. P. Wang,X. Jiang,Z. Li,D. Tian,Z. D. Wu,M. G. Yang,Z. C. Li,S. G. Yang,Y. Tu,C. He,Y. Cao,Y. Han,Jinhai Yang,S. Dong,D. F. Li,Q. F. Zhang,Z. Fan,D. Q. An,J. Liu,G. Yang,X. C. Xu,Y. Xia,H. Xu,T. Wang,D. Li,J. Wei,P. Yang,C. Y. Liu,S. Shang,Y. G. Zhang,E. Hernandez Leyva,N. Cano Lopez,A. R. Gonzalez Medina,John Kanakakis,John N. Nanas,P. Papazoglou,J. Srinivas,B. Srinivasulu,S. Dani,J. Prajapati,G. Deepak,J. F. Shallam,K. J. Nesaraj,Ashok Kumar,Rinku Sharma,S. Balasubramaniyan,N. Chidambaram,R. Umrani,Sharad Chandra,S. Dwivedi,R. Kishore,B. J. Kumar,Y. Kumble,S. Mehrotra,P. R. Nayak,S. S. Ramesh,P. K. Shetty,S. K. Trivedi,R. Beniwal,A. Kalla,R. B. Panwar,K. G. Alexander,A. V. Bindu,A. Nambiar,D. Barkavi,A. Kalanidhi,T. Pradeep,J. Rajesh,M. Ramesh,S. Shanmugasundaram,Pradeep Kumar,G. Sidhu,Rajvir Singh,K. N. Pradeep,Anubhav Mittal,J. B. Bijapure,M. S. Rao,N. G. Mohanarjun,M. B. Rao,B. R. Babu,N. Dinesh,R. K. Jain,P. A. Jiwani,S. R. Naik,T. N.C. Padmanabhan,B. S. Raju,R. Rajaram,A. S.V.N. Rao,DC Rao,V. S.P. Rao,S. Sinha,A. Bharani,G. Verma,R. K. Tongia,Sanjay Kalra,Shweta Sharma,Ravi Mehrotra,S. Sanghvi,O. P. Soni,Atanu Biswas,J. Boben,G. Jacob,Johny Joseph,A. Puri,V. K. Puri,H. Singh,R. Calton,G. K. Aneja,P. Nyayadhish,P. J. Nathani,S. K. Rane,M. Fulwani,A. S. Jain,Amal Kumar Khan,R. G. Salkar,A. Somani,R. Wadhwani,S. D. Zawar,V. E. Shegokar,S. L. Tungikar,V. Vijan,R. Trehan,A. Garg,S. Verma,S. Borade,D. Duggal,J. Hiremath,Jagdish,V.K. Katyal,H. R. Devendrappa,Ratnakar,P. B. Latha,E. B. Manoj,P.P. Mohanan,P. Gandhimadhinathan,K. Jeremaiah,B. S.V. Raj,R. Udaysankar,J. K. Chhaparwal,S. T. Chandy,Sonia Gupta,S. Raghavan,P. Ramesh,V. S. Reddy,P. Srinivas,K. D. Rao,B. R. Malipeddi,G. S.R. Murthy,Rajnish Joshi,Supriya Patil,S. Tredici,D. Agnelli,E. Assanelli,A. Bozzano,L. Marsano,R. Crivello,A. Nejrotti,A. Abdulminem,H. Saad,J. Martinez Sanchez,J. Carrillo Calvillo,A. Hamer,H. U. Banna,J. Lopez Ferre,R. J. Freedman,N. Transk,D. Almeida,P. J.C. Lujan,C. Mata,C. Becerra,Kadir González,F. Torres,M. A. Alvarez,E. Carrillo +481 more
TL;DR: In this large, international randomized trial, high-dose GIK infusion had a neutral effect on mortality, cardiac arrest, and cardiogenic shock in patients with acute STEMI.
Journal ArticleDOI
Global dissemination of a multidrug resistant Escherichia coli clone
Nicola K. Petty,Nouri L. Ben Zakour,Mitchell Stanton-Cook,Elizabeth Skippington,Makrina Totsika,Brian M. Forde,Minh-Duy Phan,Danilo Gomes Moriel,Kate M. Peters,Mark R. Davies,Mark R. Davies,Benjamin A. Rogers,Gordon Dougan,Jesús Rodríguez-Baño,Álvaro Pascual,Johann D. D. Pitout,Mathew Upton,David L. Paterson,Timothy R. Walsh,Mark A. Schembri,Scott A. Beatson +20 more
TL;DR: This study confirms the global dispersal of a single E. coli ST131 clone and demonstrates the role of MGEs and recombination in the evolution of this important MDR pathogen.
Journal ArticleDOI
Epidemiology and Clinical Features of Infections Caused by Extended-Spectrum Beta-Lactamase-Producing Escherichia coli in Nonhospitalized Patients
Jesús Rodríguez-Baño,María Dolores González-Ripoll Navarro,Luisa Romero,Luis Martínez-Martínez,Miguel A. Muniain,Evelio J. Perea,Ramón Pérez-Cano,Álvaro Pascual +7 more
TL;DR: Avoidance of fluoroquinolone use in high-risk patients should be considered whenever possible in order to avoid the selection of these organisms.
Journal ArticleDOI
Treatment of Infections Caused by Extended-Spectrum-Beta-Lactamase-, AmpC-, and Carbapenemase-Producing Enterobacteriaceae.
TL;DR: Overall, therapy of MDR-E infection must be individualized according to the susceptibility profile, type, and severity of infection and the features of the patient.